Association between coffee consumption and total dietary caffeine intake with cognitive functioning: cross-sectional assessment in an elderly Mediterranean population

Paz‐Graniel, Indira; Babió, Nancy; Becerra‐Tomás, Nerea; Toledo, Estefanía; Camacho-Barcia, Lucía; Corella, Dolores; Castañer, Olga; Romaguera, Dora; Vioque, Jesús; Alonso‐Gómez, Ángel M.; Wärnberǵ, Julia; Martínéz, J. Alfredo; Serra-Majem, Luís; Estruch, Ramón; Tinahones, Francisco J.; Fernández‐Aranda, Fernando; Lapetra, José; Pintó, Xavier; Tur, Josep A.; García‐Rios, Antonio; Bueno‐Cavanillas, Aurora; Gaforio, José J.; Matía‐Martín, Pilar; Daimiel, Lidia; Sánchez, Vicente Martín; Vidal, Josep; Prieto, Rafel M.; Ros, Emilio; Razquín, Cristina; Mestres, Gaspar; Sorlí, José V.; Cuenca‐Royo, Aida; Ríos, Ángel; Torres-Collado, Laura; Vaquero-Luna, Jessica; Pérez-Farinós, Napoleón; Zulet, M. Ángeles; Sánchez‐Villegas, Almudena; Casas, Rosa; Bernal-López, María Rosa; Santos‐Lozano, José Manuel; Corbella, Emili; Matéos, David; Buil‐Cosiales, Pilar; Jiménez‐Murcia, Susana; Fernández-Carrión, Rebeca; Forcano-Gamazo, Laura; López, Meritxell; Sempere-Pascual, Miguel Ángel; Moreno-Rodríguez, Anai; Gea, Alfredo; Torre-Fornell, Rafael de la; Salas‐Salvadó, Jordi; Investigators, PREDIMED-Plus

doi:10.1007/s00394-020-02415-w

Cited by 29 publications

(13 citation statements)

References 46 publications

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“…On the other hand, a positive association was found in the current study between caffeine intake and servings of fruit and vegetables. This result is contrary to those found in previous studies reporting associations between caffeine, or coffee intake, and negative characteristics of the diet, including low vegetable intake [36]. However, it should be considered that these studies were performed in older populations, with coffee consumers reporting higher prevalence of hypercholesterolemia and other conditions that could involve dietary limitations, while similar studies focused on caffeine consumption in university or college students or in younger populations did not consider characteristics of the diet [4][5][6]12].…”

Section: Discussioncontrasting

confidence: 80%

Caffeine Intake among Undergraduate Students: Sex Differences, Sources, Motivations, and Associations with Smoking Status and Self-Reported Sleep Quality

et al. 2022

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Due to its stimulatory effects, caffeine is one of the most frequently consumed mood and behavior altering drugs. University students report using caffeine-containing products to enhance mood and performance or for a desire of alertness. The current study investigated caffeine consumption in university undergraduate students, and associations with smoking status, alcohol and cannabis consumption, fruit and vegetable consumption, and sleep quality. Motivations for caffeine intake were also ascertained. A total of 886 undergraduates aged 18–25 years from the University of the Balearic Islands participated in a cross-sectional survey. Caffeine was consumed by 91.1% of participants. Caffeine consumers were more likely to be female, smokers, and alcohol and cannabis consumers. Coffee was found to be the main source of caffeine intake in both men and women (48.9% of total caffeine intake). Higher percentages of women consumed coffee (56.4 vs. 42.1%, p = 0.01) and tea (40.3 vs. 19.8%, p < 0.001), whereas a higher percentage of men consumed energy drinks (18.0 vs. 7.4%, p < 0.001). Main motivations for caffeine intake were those related to cognitive enhancement. Caffeine intake was associated with poorer subjective sleep quality (p < 0.001). In conclusion, undergraduate students that were female and smokers reported higher caffeine intakes. Coffee was found as the main caffeine contributor, with higher contributions of tea in women and energy drinks in men. Universities should consider the implementation of health campaigns and educational programs to educate students of the risks of high caffeine consumption together with associated behaviors such as smoking, alcohol consumption and poor sleep quality to physical health and academic performance.

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Section: Discussioncontrasting

confidence: 80%

Caffeine Intake among Undergraduate Students: Sex Differences, Sources, Motivations, and Associations with Smoking Status and Self-Reported Sleep Quality

et al. 2022

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“…The results of the behavior tests in our study showed the similar depression-like behaviors after PSD induced, and the symptom could be improved in a different extent with the treatment of conventional coffee and decaffeinated coffee (Figure 1). It has been reported that caffeinated coffee and caffeine were beneficial to depression-like behaviors, while the effect of decaffeinated coffee was not obvious (Paz-Graniel et al, 2020;Xue et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

The Impact of Instant Coffee and Decaffeinated Coffee on the Gut Microbiota and Depression-Like Behaviors of Sleep-Deprived Rats

Zhang

et al. 2022

Front. Microbiol.

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ObjectiveBased on our previous research, chronic paradoxical sleep deprivation (PSD) can cause depression-like behaviors and microbial changes in gut microbiota. Coffee, as the world’s most popular drink for the lack of sleep, is beneficial to health and attention and can eliminate the cognitive sequelae caused by poor sleep. The purpose of this study is to investigate the effects of coffee and decaffeinated coffee on PSD rats.Research Design and MethodsA total of 32 rats were divided into four groups: control group, PSD model group, conventional coffee group, and decaffeinated coffee group. Behavioral tests, including sucrose preference test, open field test, forced swimming test, and tail suspension test, as well as biochemical detection for inflammatory and antioxidant indexes were performed. The effects of coffee and decaffeinated coffee on the gut microbiota of PSD rats were investigated by 16S rRNA gene sequencing.ResultsCoffee and decaffeinated coffee significantly improved the depression-like behaviors. Moreover, the serum levels of interleukin-6 and tumor necrosis factor alpha were decreased in both coffee and decaffeinated coffee groups, as well as the levels of superoxide dismutase and GSH-Px were increased. Gut microbiota analysis revealed that the abundance of S24-7, Lachnospiraceae, Oscillospira, and Parabacteroides were significantly increased in PSD rats, while the abundance of Akkermansia and Klebsiella were significantly decreased. After the treatment of coffee and decaffeinated coffee, the abundance of the above gut microbiota was all restored in different degrees. Coffee had relatively more significant effects on PSD-induced depressive-like behaviors, while the difference between coffee and decaffeinated coffee was not obvious in correcting the disorder of gut microbiota.ConclusionsThese findings have shown that both coffee and decaffeinated coffee are effective for sleep deprivation-induced depression-like behaviors and the dysbiosis of gut microbiota and indicated that caffeine may be not the only key substance of coffee for regulating gut microbiota.

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“…These associations were not observed for decaffeinated coffee consumption. Participants in the highest tertile of total dietary caffeine intake had significantly lower odds of poor cognitive functioning than those in the lowest tertile of caffeine intake [181]. There is no specific evidence on the effects of coffee on cognitive decline in RCTs.…”

Section: Coffeementioning

confidence: 92%

Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia

et al. 2021

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Multiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for cognitive impairment and dementia is advanced age followed by other determinants such as genetic, socioeconomic, and environmental factors, including nutrition and physical activity. In the next decades, a rise in dementia cases is expected due largely to the aging of the world population. There are no hitherto effective pharmaceutical therapies to treat age-associated cognitive impairment and dementia, which underscores the crucial role of prevention. A relationship among diet, physical activity, and other lifestyle factors with cognitive function has been intensively studied with mounting evidence supporting the role of these determinants in the development of cognitive decline and dementia, which is a chief cause of disability globally. Several dietary patterns, foods, and nutrients have been investigated in this regard, with some encouraging and other disappointing results. This review presents the current evidence for the effects of dietary patterns, dietary components, some supplements, physical activity, sleep patterns, and social engagement on the prevention or delay of the onset of age-related cognitive decline and dementia.

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Association between coffee consumption and total dietary caffeine intake with cognitive functioning: cross-sectional assessment in an elderly Mediterranean population

Cited by 29 publications

References 46 publications

Caffeine Intake among Undergraduate Students: Sex Differences, Sources, Motivations, and Associations with Smoking Status and Self-Reported Sleep Quality

Caffeine Intake among Undergraduate Students: Sex Differences, Sources, Motivations, and Associations with Smoking Status and Self-Reported Sleep Quality

The Impact of Instant Coffee and Decaffeinated Coffee on the Gut Microbiota and Depression-Like Behaviors of Sleep-Deprived Rats

Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia

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