Association between COX2 -765G/C polymorphism and periodontitis in Chinese population: a meta-analysis

Zhan-shan, Zhang

doi:10.1186/s12903-018-0483-9

Cited by 9 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thes findings disagreed with (Patricia et al, 2016), [10]; who reported that the prevalence of study group according to ages were (57.1%), and (Zhang, et al, 2018), [11]; who reported that among women with cervical intraepithelial lesions aged (65-69) years was (38.8%) which was significantly higher than that of the other age groups. The mean tumor marker Ca125 was shown to be highly significant among patients with a mean age of (25.25±0.71) in comparison with the healthy controls (19.40±0.68), and these results matched with (Charkhchi, et al, 2020) [11], who reported that the tumor marker Ca125 has been used as the primary ovarian cancer marker for the past four decades and gave a highly significant levels. Also the mean of Ca15.3 (20.80±0.74) and the healthy control group (18.34±0.77), but no significant differences were found between mean levels of Ca19.9 marker (19.62±0.79) and the control group (19.21±0.71).…”

Section: Discussionmentioning

confidence: 60%

Mutation Occurrence in Ptgs2gene Sequence in Cervicitis Due to Toxoplasmosis and Cytomegalovirus Infections

Kamel¹

2023

MINAR Journal

View full text Add to dashboard Cite

In this study, venous blood samples were obtained from 100 women with Cytomegalovirus infection whose ages ranged from 18 to 60 years, and 100 healthy women as a control group. The study was conducted at Al-Elwiya teaching hospital in Baghdad city during the period from 1st November 2021 to 15th June 2022. the distrbution of study groups according to age revealed a significant difference (P=0.01) in the cervicitis patient group (34.43±11.89) in comparison with the control group (39.05±13.53). The distrbution of study groups according to the residency showed that residents of rural areas were 51(51.0%) in comparison with the control group and residents of urban areas were 49(49.0%), while the healthy control group was 51(51.0%) with no significant differences (P=0.088). A highly significant differences were bserved between the mean levels of tumor marker Ca125 in patients (25.5±0.71) in comparison with the healthy controls (19.40±0.68), and between mean levels of Ca15.3 (20.80±0.74) and the healthy control group (18.34±0.77). In addition, the mean levels of CRP was (88.06±5.88) versus the controls (6.73±0.12), with a highly significant differences (P<0.001). Also, no significant differences were seen between mean levels of Ca19.9 marker (19.62±0.79) and the control group (19.21±0.71) (P= 0.7). The distribution of polymorphism according to complete blood picture was shown in table (3) .The mean lymphocyte count was 12(60%), while there was a decrease in Hb levels 3(15%), PCV value 4(20%) and Nuetrophil count 2(10%), with no significant differences. there was no mutation occured in the analysis of rs888160762 SNP of PTGS2 gene, but showed a mutation occured in the analysis of rs20417 SNP of PTGS2 gene using Sanger sequencing. The single “C” peak indicates C homozygous alleles, while the presence of “G” and “C” peaks indicates G/C heterozygous alleles

show abstract

Section: Discussionmentioning

confidence: 60%

Mutation Occurrence in Ptgs2gene Sequence in Cervicitis Due to Toxoplasmosis and Cytomegalovirus Infections

Kamel¹

2023

MINAR Journal

View full text Add to dashboard Cite

show abstract

“…The impact of genes on teeth sexual dimorphism has also been emphasized in the literature (57)(58)(59). It is suggested that the variation in teeth sizes between and within human colonies can be the result of receiving these qualities from past generations.…”

Section: Discussionmentioning

confidence: 99%

Sexual Dimorphism in the Buccolingual Dimensions of Permanent Anterior Teeth in the Young Iranian Population

AKAD,

SOCOLOV,

COVALI

et al. 2023

Maedica

View full text Add to dashboard Cite

Objective: Evaluation of sexual dimorphism is a crucial concern for anthropologists, forensic scientists, and archaeologists. Teeth have been used as an alternative tool to determine sex in forensic anthropology. However, it is necessary to use data specific to a particular population, as different populations exhibit varying degrees of sexual dimorphism. This study aimed to determine the sexual dimorphism in the buccolingual dimensions of permanent anterior teeth in the young Iranian population.Materials and methods: A total of 100 students (50 females and 50 males) participated in the current study. A total of 1200 permanent anterior teeth were examined. The buccolingual dimension of all anterior teeth was measured using Vernier Calipers with a calibration of 0.01 mm. Data were analyzed using an independent sample T-test and paired sample T-test, and a P-value of less than 0.05 was considered statistically significant. Results:The mean values of the buccolingual dimension of the maxillary canines on the right and left sides (13,23) were statistically greater in males than females (P=0.04, P=0.03) and had the greatest percentage of sexual dimorphism (4. 08% and 5.26%, respectively).Conclusions: The buccolingual dimension of Iranian canines could be used as a reliable material to identify gender in forensic studies, and the degree of sexual dimorphism varies among different populations. Therefore, it is essential to use the relevant data samples for each population. It was concluded that Europeans had the greatest amount of sexual differences in the anterior teeth, while Iranians had the least amount of sexual dimorphism in the anterior teeth.

show abstract

“… 35 However, a meta-analysis has shown that the −765 G–C polymorphism is not significantly correlated with vascular diseases, but this might related to the sample size and different patients that were included in the studies. 36 …”

Section: Aspirin Resistance and Gene Polymorphismsmentioning

confidence: 99%

Epoxidase inhibitor-aspirin resistance and the relationship with genetic polymorphisms: a review

Hou

2024

J Int Med Res

View full text Add to dashboard Cite

Strokes are the leading cause of death in most regions of the world. Epoxidase inhibitors include the drug aspirin (acetylsalicylic acid). Aspirin is widely used as first-line treatment for the prevention of cardiovascular and cerebrovascular diseases in at-risk patients. However, patients using conventional doses of aspirin can still develop ischaemic cardiovascular and cerebrovascular diseases, a phenomenon known as aspirin resistance. The occurrence of aspirin resistance hinders the prevention and treatment of ischaemic cardiovascular and cerebrovascular diseases. There are many factors affecting aspirin resistance, such as sex, drug dose, metabolic disease, genetic polymorphisms, drug interactions and pharmacokinetics. Genetic polymorphism refers to the simultaneous and frequent presence of two or more discontinuous variants or genotypes or alleles in a population of organisms. Platelets contain a large number of highly polymorphic transmembrane glycoprotein receptors encoded by two or more isomeric alleles. Changes in gene polymorphisms in various pathways during platelet aggregation can lead to aspirin resistance. This narrative review describes the gene polymorphisms that have been demonstrated to be significantly associated with aspirin resistance. Research on the mechanisms of aspirin resistance and increased knowledge should provide accurate drug guidance in individuals that require first-line antiplatelet therapy.

show abstract

Association between COX2 -765G/C polymorphism and periodontitis in Chinese population: a meta-analysis

Cited by 9 publications

References 21 publications

Mutation Occurrence in Ptgs2gene Sequence in Cervicitis Due to Toxoplasmosis and Cytomegalovirus Infections

Mutation Occurrence in Ptgs2gene Sequence in Cervicitis Due to Toxoplasmosis and Cytomegalovirus Infections

Sexual Dimorphism in the Buccolingual Dimensions of Permanent Anterior Teeth in the Young Iranian Population

Epoxidase inhibitor-aspirin resistance and the relationship with genetic polymorphisms: a review

Contact Info

Product

Resources

About