Association between depression and heart rate variability in patients after cardiac surgery: A pilot study

Patron, Elisabetta; Benvenuti, Simone Messerotti; Favretto, Giuseppe; Valfré, Carlo; Bonfà, Carlotta; Gasparotto, Renata; Palomba, Daniela

doi:10.1016/j.jpsychores.2012.04.013

Cited by 36 publications

(28 citation statements)

References 42 publications

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“…There is a growing body of evidence suggesting that depression which develops following a major coronary event represents a significant and independent risk factor for future cardiac events [24][25][26][27]. Depression following a myocardial infarction has been shown to produce a 2 to 2.5-fold increased risk for future adverse events [28].…”

Section: Discussionmentioning

confidence: 99%

Cardiac-self efficacy predicts adverse outcomes in coronary artery disease (CAD) patients

O’Neil¹,

Berk²,

Davis³

2013

Health

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Background: Little is known about the predictive role of Cardiac Self Efficacy (CSE) in the ensuing months following a coronary event. We sought to determine whether CSE predicts adverse events in the months following discharge in patients with Coronary Artery Disease (CAD). Design: Data from a prospective study of 193 patients recently hospitalized for CAD. Methods: Data were collected via participant self-report and medical records at 3-month post-discharge (baseline; T1), 6-month post-discharge (T2) and 9-month post-discharge (T3). CSE was measured using the Cardiac Self Efficacy Scale. Multi-variate regression modeling was applied to explore the association between baseline CSE scores and cardiac-related hospital admissions and functional cardiac status at T2 and T3. Other outcomes included any hospital admissions, self-reported mental and physical health at follow up. Results: Higher CSE scores at baseline significantly predicted better cardiac functioning and self-rated mental and physical health at both T2 and T3 (with one exception); this was consistent across all five models. While baseline CSE did not predict cardiac or other hospital admission at T2, CSE was a significant predictor of both outcomes at T3; higher CSE scores resulted in reductions in likelihood of hospital admissions. After adjustment for psychosocial variables however, neither association remained. Baseline depression explained the association between baseline CSE and any cardiac admissions, as well as baseline CSE and any hospital admissions at T3 follow up. Conclusions: While CSE can predict key outcomes following a CAD event, much of the association can be explained by the presence of depression.

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Section: Discussionmentioning

confidence: 99%

Cardiac-self efficacy predicts adverse outcomes in coronary artery disease (CAD) patients

O’Neil¹,

Berk²,

Davis³

2013

Health

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“…The Holter data was first cleaned to remove artifact and then analyzed with Sentinel Impresario Holter, version 7.1.3 (Spacelabs Healthcare, Hertford, UK). A single time-domain measure of heart rate variability—standard deviation of N-N intervals (SDNN)—was chosen a priori for analyses because it is valid over short periods of time and because it has been used in previous literature examining vagal tone in conditions of psychological stress (Clays et al, 2011; Lee & Theus, 2012; Patron et al, 2012). …”

Section: Methodsmentioning

confidence: 99%

Age, stress, and isolation in older adults living with HIV

et al. 2013

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People living with HIV (PLWH) have increasingly longer life spans. This age group faces different challenges than younger PLWH, which may include increased stress and social isolation. The purpose of this study was to determine if the age and sex of PLWH is associated with measures of physiologic stress, perceived stress and social isolation. In this cross-sectional study, we enrolled 102 PLWH equally into four groups divided by age (< or > 50 years) and gender. Participants completed well-validated survey measurements of stress and isolation, and their heart rate variability over 60 minutes was measured by Holter monitor. The mean (standard deviation) Perceived Stress Scale score was 17.4 (6.94), mean visual analog stress scale score was 3.51 (2.79), and mean Hawthorne Friendship Scale score, a measure of social isolation, was 17.03 (4.84). Mean heart rate variability expressed as the standard deviation of successive N-N intervals was 65.47 (31.16) msec. In multivariable regression models that controlled for selected demographic variables, there was no relationship between the Perceived Stress Scale and age (coefficient=−0.09, p=−.23) or female gender (coefficient=−0.12, p=0.93); however, there was a modest relationship between female gender and stress using the visual analog stress scale (coefficient=1.24, p=0.05). Perceived Stress was negatively associated with the Hawthorne Friendship score (coefficient=−0.34, p=0.05). Hawthorne Friendship score was positively associated with younger age (coefficient=0.11, p=0.02). Age was the only independent predictor of physiologic stress as measured by heart rate variability (coefficient=−1.3, p<0.01). Our findings suggest that younger PLWH may experience more social isolation; however, age-related changes in heart rate variability do not appear to be related to perceived stress or social isolation. Future longitudinal research is required to more thoroughly understand this relationship and its impact on the health of PLWH.

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“…Thayer and Lane (2007) noted that all modifiable risk factors for CVD (e.g. HRV parameters have been shown to negatively correlate with depression severity in patients with CVD (Stein et al, 2000) and after ACS (Carney et al, 2001), and reduced HRV persists in patients with depression following cardiac surgery (Patron et al, 2012). A reduction of HRV has been associated with poor modulation of cardiovascular responses, an increased propensity to inflammation and poorer health outcomes in ACS patients (Carney et al, 2007;Thayer and Lane, 2007).…”

Section: The Importance Of Autonomic Regulationmentioning

confidence: 99%

Acute coronary syndrome and depression: A review of shared pathophysiological pathways

Smith

Parker

Rourke

et al. 2015

Aust N Z J Psychiatry

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Association between depression and heart rate variability in patients after cardiac surgery: A pilot study

Cited by 36 publications

References 42 publications

Cardiac-self efficacy predicts adverse outcomes in coronary artery disease (CAD) patients

Cardiac-self efficacy predicts adverse outcomes in coronary artery disease (CAD) patients

Age, stress, and isolation in older adults living with HIV

Acute coronary syndrome and depression: A review of shared pathophysiological pathways

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