Association between depression and non-fatal overdoses among drug users: A systematic review and meta-analysis

Bartoli, Francesco; Carrà, Giuseppe; Brambilla, Giulia; Carretta, Daniele; Crocamo, Cristina; Neufeind, Julia; Baldacchino, Alex; Humphris, Gerry; Clerici, Massimo

doi:10.1016/j.drugalcdep.2013.10.007

Cited by 55 publications

(29 citation statements)

References 69 publications

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“…11 Our findings of an association between anxiety disorders and a history of OD and intentional OD are similar to work by Maloney and colleagues 12 with adults with opioid use disorders. They found that anxiety disorders were linked with a history of suicide attempt but not with unintentional OD.…”

Section: Discussionsupporting

confidence: 88%

“…9,10 Psychiatric risk factors associated with OD in substance users include depression 11 and increased impulsivity. 12 Likewise, a history of a suicide attempt has also been associated with history of OD in substance users 5,13,14 although many of the studies that examined this relationship did not evaluate for differences related to the intentionality of the OD.…”

Section: Introductionmentioning

confidence: 99%

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Risk Factors for Overdose in Treatment-Seeking Youth With Substance Use Disorders

Yule¹,

Carrellas²,

Fitzgerald³

et al. 2018

J. Clin. Psychiatry

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Objective Overdoses (OD) are among the leading causes of death in youth with substance use disorders (SUDs). We aimed to identify the prevalence of OD and characteristics associated with a history of OD in youth presenting for SUD outpatient care. Methods Systematic retrospective medical record review of consecutive psychiatric and SUD evaluations for patients age 16 to 26 years at entry into an outpatient SUD treatment program for youth. Unintentional OD was defined as substance use without intention of self-harm that was associated with a significant impairment in level of consciousness. Intentional OD was defined as ingestion of a substance that was reported as a suicide attempt. T-tests, Pearson’s chi-square, and Fisher’s exact tests were performed to evaluate characteristics associated with a history of OD. Results We examined the medical records of 200 patients (157 males and 43 females) with mean age 20.2 (±) 2.8 years. At intake 58 patients (29%) had a history of OD and 62% of those patients had a history of unintentional OD only (n=36). Youth with ≥2 SUDs were 3 times more likely to have a history of OD compared to youth with 1 SUD (all p<0.05). Compared to those without a history of OD those with an OD were more likely to be female and have lifetime histories of: alcohol, cocaine, amphetamine, anxiety, depressive, and/or eating disorders (all p<0.05). Conclusion High rates of OD exist in treatment-seeking youth with SUD. OD was associated with more SUD and psychiatric co-morbidity.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Risk Factors for Overdose in Treatment-Seeking Youth With Substance Use Disorders

Yule¹,

Carrellas²,

Fitzgerald³

et al. 2018

J. Clin. Psychiatry

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“…This is slightly higher than rates of other studies from similar geographical areas [21, 22], representing a potential serious risk to public health, because of high risk of adverse consequences [14]. There is the need of developing specific interventions for primary and secondary prevention, and public health research should focus on new programs that may reduce rates of binge drinking or, at least, its adverse health outcomes [27, 60]. At the same time, prevention strategies should be linked with changes of general public attitudes often considering binge drinking as an acceptable “rite of passage” of adolescents and young adults, with fewer dangerous health consequences than other illicit substance-related risky behaviors [3].…”

Section: Discussionmentioning

confidence: 95%

Prevalence and Correlates of Binge Drinking among Young Adults Using Alcohol: A Cross-Sectional Survey

Bartoli

Carretta

Crocamo

et al. 2014

BioMed Research International

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Background. Although binge drinking prevalence and correlates among young people have been extensively studied in the USA and Northern Europe, less is known for Southern Europe countries with relatively healthier drinking cultures. Objective. We aimed at analyzing prevalence and correlates of binge drinking in a representative sample of young adults in Italy. Methods. We conducted a cross-sectional survey among alcohol-consuming young adults. We carried out univariate and multivariate analyses to assess associations between recent binge drinking and candidate variables. Results. We selected 654 subjects, with 590 (mean age: 20.65 ± 1.90) meeting inclusion criteria. Prevalence for recent binge drinking was 38.0%, significantly higher for females than males. Multivariate analysis showed that high alcohol expectancies, large amount of money available during the weekend, interest for parties and discos, female gender, cannabis use, influence by peers, and electronic cigarettes smoking all were significantly associated with recent binge drinking, whereas living with parents appeared a significant protective factor. Conclusions. More than a third of young adults using alcohol are binge drinkers, and, in contrast with findings from Anglo-Saxon countries, females show higher risk as compared with males. These data suggest the increasing importance of primary and secondary prevention programmes for binge drinking.

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“…Embora, o uso de drogas esteja associado a diversas doenças físicas e mentais, é percebida há tempo sua forte relação ao risco de mortalidade precoce por overdose. Trata-se da principal causa de morte entre os usuários, sobretudo as acidentais, aquela que ocorre sem a intensão prévia do usuário 17 . As comorbidades mentais apresentadas por 41,3% dos participantes desta pesquisa, dentre esses se destacaram os transtornos mentais com psicose e os de humor sem psicose.…”

Section: Revista Saúde E Pesquisaunclassified

Consequências Do Uso Abusivo De Substâncias Psicoativas Por Pessoas Em Tratamento

Capistrano

Maftum²,

Mantovani

et al. 2018

SaudPesq

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RESUMO:Este artigo tem como objetivo caracterizar o impacto do uso abusivo de substâncias psicoativas para a pessoa com transtorno relacionado a substâncias. Trata-se de um estudo quantitativo, analítico e transversal, com 163 pacientes de um Centro de Atenção Psicossocial Álcool e Drogas. Os dados foram coletados com a aplicação individual de um instrumento estruturado e analisados por meio descritivo e estatístico com teste de correlação de Person, Teste de Média e Qui-quadrado. Como resultado identificou-se que a maioria são homens, que utilizam álcool e crack, baixa escolaridade, solteiro, desempregado e baixa renda. Houve abandono escolar, problemas laborais e mudança de ocupação. Tiveram episódios de overdoses, suicídios, comorbidades mentais, físicas, comportamento sexual de risco, Doenças Sexualmente Transmissíveis (DST's), agressões físicas, crimes e acidentes de trânsito. Foi identificado histórico do uso de drogas, rompimento de vínculos, separação, abandono do lar e situação de rua. Conclui-se que o uso abusivo de drogas afeta as pessoas direta e indiretamente em todos os âmbitos da vida, pessoal, laboral e acadêmico e social. PAlAVRAS-ChAVE:Transtornos relacionados ao uso de substâncias; Saúde mental; Enfermagem psiquiátrica. CONSEQUENCES OF ABUSE FROM PSYChOACTIVE SUBSTANCES BY PEOPlE UNDER TREATMENT ABSTRACT:The impact of psychoactive substances on the person with disorders related to illegal drugs is analyzed. Current quantitative, analytic and transversal study comprised 163 patients from an Alcohol and Drug First Aid Center. Data were retrieved by applying a structured tool to each individual and analyzed descriptively and statistically by Pearson´s correlation test and by mean and Chi-square tests. Results show that most people who take alcohol and crack have low schooling level, they are single, unemployed and have a low income. Schooling was forsaken at an early age and work problems and occupation changes occurred, coupled to overdose episodes, suicide attempts, mental and physical co-morbidity, risky sexual behavior, sexually transmitted diseases (STDs), physical aggressions, crimes and street traffic accidents. A history of drug use, breaking of family bonds, separation, abandonment of home and street living was constant. Results show that the abuse of drugs affects people directly and indirectly with regard to their personal, labor, academic and social life.

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Association between depression and non-fatal overdoses among drug users: A systematic review and meta-analysis

Cited by 55 publications

References 69 publications

Risk Factors for Overdose in Treatment-Seeking Youth With Substance Use Disorders

Risk Factors for Overdose in Treatment-Seeking Youth With Substance Use Disorders

Prevalence and Correlates of Binge Drinking among Young Adults Using Alcohol: A Cross-Sectional Survey

Consequências Do Uso Abusivo De Substâncias Psicoativas Por Pessoas Em Tratamento

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