Association between dietary inflammatory index and inflammatory markers in the HELENA study

Shivappa, Nitin; Hébert, James R.; Rietzschel, Ernst; Buyzere, Marc L. De; Langlois, Michel; Debruyne, Evi; Marcos, Ascensión; Huybrechts, Inge

doi:10.1002/mnfr.201600707

Cited by 349 publications

(243 citation statements)

References 68 publications

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“…The inflammatory potential of the diet was evaluated by the DII. The DII has been validated in previous studies with different measures of inflammation such as C‐reactive protein (CRP), IL‐6, and TNF‐α‐R2 (Shivappa et al, ; Wirth et al, ). Additionally, the DII has also been reported to be associated with several chronic inflammation‐related health outcomes such as cancer incidence and CVD (Bodén et al, ; Bondonno et al, ; Garcia‐Arellano et al, ; O'Neil et al, ; Ramallal et al, ; Zheng et al, ).…”

Section: Methodsmentioning

confidence: 99%

Dietary inflammatory index and cardiovascular risk factors in Spanish children and adolescents

Correa‐Rodríguez¹,

González‐Jiménez²,

Rueda‐Medina³

et al. 2018

Research in Nursing & Health

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Dietary inflammatory potential is an established risk factor for adverse cardiovascular events. In this study we analyzed the relation between the Dietary Inflammatory Index (DII) and cardiovascular risk factors, based on anthropometric, body composition, blood pressure, and heart rate parameters in children and adolescents. We conducted a cross-sectional study of 428 Spanish schoolchildren (mean age 12.32 ± 1.84), whose DII was calculated, based on a 24-hr diet recall over 3 days. Anthropometric measurements were taken, and body composition analyzed by bioelectrical impedance analysis. Blood pressure and heart rate parameters were assessed with an automatic monitor. Pubertal stage was assessed based on Tanner criteria. We analyzed the DII both as a continuous variable and as a category variable based on quartiles. Linear regression analysis revealed that the DII was significantly associated with waist to height ratio (WHtR) (p = .026; B = 0.128, 95% CI [.001-.016]) after adjusting for age, sex, total energy intake, and Tanner stage. All macro- and micronutrient intakes were found to be higher in the DII Q1 (anti-inflammatory diet) except for caffeine. This study provides preliminary evidence of a significant association between the DII and WHtR, an index of cardiovascular risk. The results obtained indicate that the inflammatory potential of the diet may play a role in children and adolescents becoming overweight or developing obesity. Future studies in young people should be conducted to validate and further explore these relationships.

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Section: Methodsmentioning

confidence: 99%

Dietary inflammatory index and cardiovascular risk factors in Spanish children and adolescents

Correa‐Rodríguez¹,

González‐Jiménez²,

Rueda‐Medina³

et al. 2018

Research in Nursing & Health

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“…The DII minimum/maximum in nonpregnant populations is reported to range from −8.87 to +7.98 (Shivappa, Steck, Hurley, Hussey, & Hébert, ). DII score has already been validated in nonpregnant adults to correlate with various inflammatory markers including CRP, tumour necrosis factor alpha (TNF‐α), and interleukin (IL)‐6 (Shivappa et al, ; Shivappa et al, ).…”

Section: Calculation Of DIImentioning

confidence: 99%

Effect of proinflammatory diet before pregnancy on gestational age and birthweight: The Japan Environment and Children's Study

Ishibashi

Kyozuka

Fujimori

et al. 2019

Maternal & Child Nutrition

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The daily diet plays a role in systematic inflammation and may be one of the causes of preterm birth. We aimed to examine the effect of a daily proinflammatory diet before pregnancy on gestational age and birthweight using a large birth cohort in Japan. We used data of singleton pregnancies in the Japan Environment and Children's Study involving live birth from 2011 to 2014 to calculate the dietary inflammatory index. We used individual meals with 30 food parameters from a semiquantitative food frequency questionnaire, which assessed diet intake before pregnancy. Participants were categorized according to the quartile of dietary inflammatory index. A multiple logistic regression model was used to estimate the risk of a proinflammatory diet on preterm birth (PTB) before 37 or 34 weeks and low birthweight (LBW) less than 2,500 or 1,500 g, accounting for maternal age, body mass index before pregnancy, smoking status, education, and household income. After applying our inclusion criteria, 89,329 participants were eligible for the present study. Multiple regression analysis showed that the proinflammatory diet had an increased risk of PTB < 34 weeks (adjusted odds ratio: 1.29, 95% confidence interval [1.07, 1.55]) and <2,500‐g LBW (adjusted odds ratio: 1.08, 95% confidence interval [1.01, 1.16]) compared with the control. In conclusion, a proinflammatory diet before pregnancy was a risk factor for PTB < 34 weeks and LBW < 2,500 g. Therefore, proinflammatory diet needs to be controlled to improve perinatal prognosis.

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“…), are involved in nutrition pathways that could reduce low-grade systemic inflammation [34, 44]. Previous NHANES [45] and other studies [46–49] have validated the DII against various inflammatory markers (i.e., CRP) and have shown a high level of correlation between the two.…”

Section: Discussionmentioning

confidence: 99%

Dietary inflammatory potential is linked to cardiovascular disease risk burden in the US adult population

Tyrovolas

Koyanagi

Kotsakis

et al. 2017

International Journal of Cardiology

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Background Dietary guidelines are a key tool in the public health quiver. Single nutrients have been linked to cardiovascular diseases, but existing metrics do not capture the overall effect of diet on inflammatory diseases. The aim of this study was to examine the association between dietary inflammatory potential and cardiovascular diseases risk factors (CVD-RFs) in a nationally-representative sample of non-institutionalized US adults using data from the continuous National Health and Nutrition Examination Survey (NHANES) (2007–2012). Methods and Results A sample of 7,880 non-institutionalized US adults aged ≥20 years provided data on dietary habits and CVD-RFs (obesity; diabetes mellitus; hypertension; hypercholesterolemia). The total number of CVD-RFs was summed for each individual to create a CVD-RF morbidity index (range 0–4) as the outcome variable, used both as ordinal and dichotomous (no CVD-RFs versus at least one CVD-RF) variables. The association between the Dietary Inflammatory Index (DII) and at least one CVD-RF was dose-dependent, with participants in the 3rd and 4th quartile of DII (i.e., more pro-inflammatory dietary habits) being 1.37 (95%CI=1.11–1.68) and 1.50 (95%CI=1.19–1.90) times more likely, respectively, to have at least one CVD-RF, as compared to participants in the 1st quartile of DII scores. Similar results were obtained for the ordinal logistic regression using the CVD-RF morbidity index as the outcome. Conclusions Among US adults aged ≥20 years, pro-inflammatory dietary patterns, as assessed by the DII, were associated with increased odds for CVD-RFs. Dietary guidelines aimed at lowering the DII may reduce the CVD-RF burden in US adults.

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Association between dietary inflammatory index and inflammatory markers in the HELENA study

Cited by 349 publications

References 68 publications

Dietary inflammatory index and cardiovascular risk factors in Spanish children and adolescents

Dietary inflammatory index and cardiovascular risk factors in Spanish children and adolescents

Effect of proinflammatory diet before pregnancy on gestational age and birthweight: The Japan Environment and Children's Study

Dietary inflammatory potential is linked to cardiovascular disease risk burden in the US adult population

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