Association between different cutoff points for objectively measured moderate-to-vigorous physical activity and cardiometabolic markers in older adults

Santos, Carla Elane Silva dos; d’Orsi, Eleonora; Rech, Cassiano Ricardo

doi:10.1016/j.archger.2020.104238

Cited by 6 publications

(5 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first study indicated that 60–75 min/day of MVPA was needed to eliminate the higher risk of death associated with SB [ 41 ], while the latter indicated only 30–40 min/day [ 4 ]. The difference between these two studies (30–45 min) can be of clinical importance in predominately sedentary patients with CAD; however, such discrepancies between studies can also be associated with the use of different levels of cut-off values for MVPA and SB [ 42 ]. For example, a different cut-off point for MVPA has provided conflicting estimates of cardiometabolic health in older adults [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

Objectively Measured Physical Activity in Patients with Coronary Artery Disease: A Cross-Validation Study

et al. 2021

View full text Add to dashboard Cite

Physical activity (PA) and sedentary behavior (SB) levels in healthy adults are predominately based on self-reporting measures, which generally overestimate PA but underestimate SB. Patients with coronary artery disease (CAD) eligible for cardiac rehabilitation (CR) follow an individualized program; thus, objective assessment of physical performance and regular daily activity is required. This study aimed to compare self-reported and objectively measured PA and SB in patients with CAD prior to out-patient CR. We included 91 patients with CAD and assessed their PA with an accelerometer for 8 days prior to CR, along with the short form of the international physical activity questionnaire. We found that most patients were sedentary (61%, ~8 h/day), and on average performed 63 min/day of moderate-to-vigorous-intensity physical activity (MVPA). Males performed less daily light-intensity physical activity (−5%, p = 0.011) and performed more MVPA (+2%, p = 0.002) compared to females. Maximal aerobic capacity was significantly associated with MVPA (Spearman rho = 0.483, p < 0.001) and MVPA >10 min bouts (Spearman rho = 0.391, p < 0.001). Self-reported measures overestimated MVPA (total MVPA, +108 min/day, p < 0.001; MVPA >10 min bouts, +152 min, p < 0.001) and underestimated SB (−174 min/day, p < 0.001) compared to objective measures. There was no significant correlation between methods in MVPA (Spearman rho = 0.147, p = 0.165)), MVPA >10 min bouts (Spearman rho = −0.059, p = 576), and SB (Spearman rho = 0.139, p = 0.187). Quantitative analysis demonstrated the huge proportional bias for MVPA, MVPA >10 min bouts, and SB. Our findings demonstrate that self-reported physical activity provides inaccurate estimates of MVPA and SB in patients with CAD entering the ambulatory CR. This strongly supports the more objective assessments of daily PA, preferably using an accelerometer.

show abstract

Section: Discussionmentioning

confidence: 99%

Objectively Measured Physical Activity in Patients with Coronary Artery Disease: A Cross-Validation Study

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Given the difficulty of an accurate estimation of gait speed in real-world situations, most existing commercial wearable devices still deploy the more straightforward classical approach for PA assessment, by providing only an estimation of PA intensity levels (time spent in sedentary, light, moderate, and vigorous intensities). The issue with this approach is that the processing of raw data (acceleration signal) and definition of thresholds to classify intensity levels differ between various devices, making difficult comparison of PA-related outcome measures across studies/clinical populations 28 , 29 . The assessment of PA using gait speed as an outcome measure may overcome this issue since walking/gait characterized by speed is an 'invariant' component of PA.…”

Section: Introductionmentioning

confidence: 99%

Real-world gait speed estimation, frailty and handgrip strength: a cohort-based study

Soltani

Abolhassani

Marques‐Vidal

et al. 2021

Sci Rep

View full text Add to dashboard Cite

Gait speed is a reliable outcome measure across multiple diagnoses, recognized as the 6th vital sign. The focus of the present study was on assessment of gait speed in long-term real-life settings with the aim to: (1) demonstrate feasibility in large cohort studies, using data recorded with a wrist-worn accelerometer device; (2) investigate whether the walking speed assessed in the real-world is consistent with expected trends, and associated with clinical scores such as frailty/handgrip strength. This cross-sectional study included n = 2809 participants (1508 women, 1301 men, [45–75] years old), monitored with a wrist-worn device for 13 consecutive days. Validated algorithms were used to detect the gait bouts and estimate speed. A set of metrics were derived from the statistical distribution of speed of gait bouts categorized by duration (short, medium, long). The estimated usual gait speed (1–1.6 m/s) appears consistent with normative values and expected trends with age, gender, BMI and physical activity levels. Speed metrics significantly improved detection of frailty: AUC increase from 0.763 (no speed metrics) to 0.798, 0.800 and 0.793 for the 95th percentile of individual’s gait speed for bout durations < 30, 30–120 and > 120 s, respectively (all p < 0.001). Similarly, speed metrics also improved the prediction of handgrip strength: AUC increase from 0.669 (no speed metrics) to 0.696, 0.696 and 0.691 for the 95th percentile of individual’s gait speed for bout durations < 30, 30–120 and > 120 s, respectively (all p < 0.001). Forward stepwise regression showed that the 95th percentile speed of gait bouts with medium duration (30–120 s) to be the best predictor for both conditions. The study provides evidence that real-world gait speed can be estimated using a wrist-worn wearable system, and can be used as reliable indicator of age-related functional decline.

show abstract

“…Additionally, enormous variation around the mean was present, which is normal in studies assessing PA levels ( dos Santos et al, 2020 ). It is worth highlighting that although different cut-offs have been published to determine MVPA levels ( dos Santos et al, 2020 ), the objectively measured MVPA in the present study ensured a robust PA assessment. The lack of association between MVPA and vascular health markers contradicts our initial hypothesis and previous studies ( Park et al, 2017 ; Germano-Soares et al, 2018 ).…”

Section: Discussionmentioning

confidence: 97%

“…On average, male and female participants performed 35 ± 39.4 and 19 ± 20.4 min/day of MVPA, with 44% and 33% of them meeting current PA guidelines (Izquierdo et al, 2021). Additionally, enormous variation around the mean was present, which is normal in studies assessing PA levels (dos Santos et al, 2020). It is worth highlighting that although different cut-offs have been published to determine MVPA levels (dos Santos et al, 2020), the objectively measured MVPA in the present study ensured a robust PA assessment.…”

Section: Discussionmentioning

confidence: 99%

Associations between physical activity and cardiorespiratory fitness with vascular health phenotypes in older adults: a cross-sectional study

et al. 2023

View full text Add to dashboard Cite

Objective: We investigated the associations between physical activity (PA) and cardiorespiratory fitness (CRF) with vascular health phenotypes in community-dwelling older adults.Methods: This cross-sectional study included 82 participants (66.8 ± 5.2 years; 81% females). Moderate-to-vigorous physical activity (MVPA) was assessed using accelerometers, and CRF was measured using the distance covered in the 6-min walk test (6MWT). The vascular health markers were as follows: i) arterial function measured as aortic pulse wave velocity (aPWV) estimated using an automatic blood pressure device; and ii) arterial structure measured as the common carotid intima-media thickness (cIMT). Using a combination of normal cIMT and aPWV values, four groups of vascular health phenotypes were created: normal aPWV and cIMT, abnormal aPWV only, abnormal cIMT only, and abnormal aPWV and cIMT. Multiple linear regression was used to estimate the beta coefficients (β) and their respective 95% confidence intervals (95% CI) adjusting for BMI, and medication for diabetes, lipid, and hypertension, sex, age, and blood pressure.Results: Participants with abnormal aPWV and normal cIMT (β = −53.76; 95% CI = −97.73—−9.78 m; p = 0.017), and participants with both abnormal aPWV and cIMT (β = −71.89; 95% CI = −125.46—−18.31 m; p = 0.009) covered less distance in the 6MWT, although adjusting for age, sex and blood pressure decreased the strength of the association with only groups of abnormal aPWV and cIMT covering a lower 6MWT distance compared to participants with both normal aPWV and cIMT (β = −55.68 95% CI = −111.95–0.59; p = 0.052). No associations were observed between MVPA and the vascular health phenotypes.Conslusion: In summary, poor CRF, but not MVPA, is associated with the unhealthiest vascular health phenotype (abnormal aPWV/cIMT) in older adults.

show abstract

Association between different cutoff points for objectively measured moderate-to-vigorous physical activity and cardiometabolic markers in older adults

Cited by 6 publications

References 28 publications

Objectively Measured Physical Activity in Patients with Coronary Artery Disease: A Cross-Validation Study

Objectively Measured Physical Activity in Patients with Coronary Artery Disease: A Cross-Validation Study

Real-world gait speed estimation, frailty and handgrip strength: a cohort-based study

Associations between physical activity and cardiorespiratory fitness with vascular health phenotypes in older adults: a cross-sectional study

Contact Info

Product

Resources

About