Association between erectile dysfunction, cardiovascular risk factors, and coronary artery disease: Role of exercise stress testing and International Index of Erectile Function (IIEF-5) questionnaire

Memon, Shakeel Ahmed; Adil, Muhammad; Khan, Fahad; Ullah, Safi; Rehmat, Samra; Gul, Nooh Zad

doi:10.1016/j.ijcha.2022.101033

Cited by 7 publications

(1 citation statement)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Predictors of vascular risk, including obesity, hyperlipidemia, metabolic syndrome, diabetes mellitus and hypertension, are associated with the presence of ED and vascular endothelial dysfunction [11]. The relationship between arteriosclerosis and erectile dysfunction has been previously reported [12,13].…”

Section: Introductionmentioning

confidence: 94%

Relationship between diagonal earlobe crease (Frank's sign) and international index of erectile dysfunction score (IIEF-5)

2023

Journal of Men's Health

View full text Add to dashboard Cite

The objective of this study is to examine the association between erectile dysfunction (ED) and the presence of diagonal earlobe crease (DELC), a physical sign commonly associated with atherosclerosis. A total of 96 male patients, aged between 50 and 65 years, were referred to our institute between December 2020 and March 2021 for various urological conditions. These patients were included in the study. Erectile performance was assessed using the IIEF-5 score, and DELC was visually identified by a urologist. The patients were administered the IIEF-5 questionnaire, and the results were categorized into two groups: the DELC group included patients with an earlobe crease, while non-DELC group consisted of patients with normal earlobes. In total, 96 patients participated in the study. We observed a decrease in IIEF-5 scores among patients in the DELC group compared to those in the non-DELC group. A statistically significant difference was found between the DELC group and the non-DELC group (p < 0.01). This study demonstrates that the presence of an earlobe crease may serve as a predictive sign of atherogenic erectile dysfunction in male patients aged 50–65 years. Further investigations should be conducted to explore the utility of DELC as a standard indicator during the physical examination of erectile dysfunction.

show abstract

Section: Introductionmentioning

confidence: 94%

Relationship between diagonal earlobe crease (Frank's sign) and international index of erectile dysfunction score (IIEF-5)

2023

Journal of Men's Health

View full text Add to dashboard Cite

show abstract

Exploring the bidirectional link between erectile dysfunction and 10-year cardiovascular risk in men with diabetes and hypertension

Nguyen Ngoc Dang,

Viet Luong,

Kiem Pham

et al. 2024

Sci Rep

View full text Add to dashboard Cite

Erectile dysfunction (ED) shares common risk factors with cardiovascular (CV) disease, such as a sedentary lifestyle, obesity, and metabolic syndrome. However, the relationship between ED and CV risk in Vietnam remains unknown. To investigate this, we conducted a multi-center observational study, randomly selecting 2,936 men aged 40 to 69 years in Vietnam, with 385 participants included after exclusions. The study evaluated the 10-year CV risk using the Systematic Coronary Risk Evaluation 2-Diabetes (SCORE2-Diabetes) score and assessed ED using the International Index of Erectile Function (IIEF-5) score. Results showed that men with diabetes mellitus and hypertension had significantly lower IIEF-5 scores compared to healthy individuals (18 [15–22] vs. 23 [20–24], p < 0.001). Additionally, the IIEF-5 score proved effective in identifying patients at very high CV risk, with an area under the curve (AUC) of 0.747, a cutoff point of 18.5, sensitivity of 69.6%, and specificity of 69.9%. Furthermore, we found a significant inverse correlation between SCORE2-Diabetes and IIEF-5 (ρ = -0.45 and p < 0.001). These findings establish a significant connection between ED and CV risk in men with diabetes, underscoring the need for integrated screening and management strategies to address both conditions concurrently. Supplementary Information The online version contains supplementary material available at 10.1038/s41598-024-78182-z.

show abstract

Markov Model-Based Sports Training Risk Prediction Model Design and Its Training Control

Huang

Wen

2022

Journal of Sensors

View full text Add to dashboard Cite

With the improvement of living standard, people gradually start to pay attention to physical health and figure maintenance, and sports training also gradually becomes a hot issue for people. Sports training can help people develop a healthy body and cultivate a persevering spirit, which can be of great help in all aspects of people’s development, but sports training also has a certain degree of risk, and only a reasonable response can make sports training give maximum value. In this paper, a Markov model is established, a probability transfer matrix is calculated, and this matrix is used to predict the risks arising from sports training since the statistical decade, and the risks of sports training in the next three years are predicted, and some suggestions are made for how to minimize and avoid the risks.

show abstract

Association between erectile dysfunction, cardiovascular risk factors, and coronary artery disease: Role of exercise stress testing and International Index of Erectile Function (IIEF-5) questionnaire

Cited by 7 publications

References 51 publications

Relationship between diagonal earlobe crease (Frank's sign) and international index of erectile dysfunction score (IIEF-5)

Relationship between diagonal earlobe crease (Frank's sign) and international index of erectile dysfunction score (IIEF-5)

Exploring the bidirectional link between erectile dysfunction and 10-year cardiovascular risk in men with diabetes and hypertension

Markov Model-Based Sports Training Risk Prediction Model Design and Its Training Control

Contact Info

Product

Resources

About