Association between food intake patterns and serum vitamin D concentrations in US adults

Ganji, Vijay; Shi, Zumin; Al-Abdi, Tamara; Hejap, Dalia Al; Attia, Yasmine; Koukach, Dalya; Elkassas, Hind

doi:10.1017/s0007114522001702

Cited by 4 publications

(2 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The ONPL pattern explained 6.6% of the variance. A total of 20.7% variance was explained by all three dietary patterns, which is similar to the published reports [31]. 2 Factor analysis method was used to extract three principal factors.…”

Section: Dietary Intake Patterns Descriptionsupporting

confidence: 78%

Dietary Patterns and Hypothyroidism in U.S. Adult Population

Alkhatib,

Shi,

Ganji

2024

Nutrients

Self Cite

View full text Add to dashboard Cite

The thyroid gland produces hormones that are essential for various body functions. Hypothyroidism is defined as insufficient thyroid hormone production. Several studies have found associations between specific micronutrients and overall thyroid function; however, the amount of evidence regarding the relationship between dietary patterns and hypothyroidism among the U.S. population is limited. Data from three cycles of National Health and Nutrition Examination Surveys (NHANES), 2007–2008, 2009–2010, and 2011–2012, were used (n = 8317). Subjects with serum thyroid stimulating hormone >4.5 mIU/L or on levothyroxine were considered to have hypothyroidism. Age, sex, race/ethnicity, body mass index, and several lifestyle factors were considered as covariates. Three patterns were extracted using factor analysis. These were labeled as fat–processed grains–sugars–meats (FPSM), oils–nuts–potatoes–low-fat meats (ONPL), and fruits–whole grains–vegetables–dairy (FWVD) patterns. In a weighted multiple logistic regression, FPSM and ONPL were inversely associated with hypothyroidism (OR, 0.75; 95% CI, 0.57–1; p = 0.049 and OR, 0.81; 95% CI, 0.67–0.97; p = 0.025, respectively). However, FWVD demonstrated no association with hypothyroidism (p = 0.63). In conclusion, FPSM and ONPL patterns but not FWVD patterns were associated with hypothyroidism in U.S. adults. Nutrient deficiencies and their interactions may be linked to hypothyroidism.

show abstract

Section: Dietary Intake Patterns Descriptionsupporting

confidence: 78%

Dietary Patterns and Hypothyroidism in U.S. Adult Population

Alkhatib,

Shi,

Ganji

2024

Nutrients

Self Cite

View full text Add to dashboard Cite

show abstract

“…Many natural food sources of vitamin D are limited in the average diet, therefore, reaching the optimal vitamin D intake through dietary diversification might be difficult. Specific food patterns, like high consumption of processed food and low consumption of vegetables, fruits, nuts, whole grains, and fish may also predispose people to an inadequate vitamin D status [24].…”

Section: Introductionmentioning

confidence: 99%

Fortification of Staple Foods for Household Use with Vitamin D: An Overview of Systematic Reviews

Nyakundi,

Némethné Kontár,

Kovács

et al. 2023

Nutrients

View full text Add to dashboard Cite

Vitamin D deficiency is a global public health concern with significant implications for bone health and chronic disease prevention. Our aim was to summarize the evidence from Cochrane and other systematic reviews evaluating the benefits or harms of vitamin D fortification of staple foods for household use. In April 2023, we systematically searched Ovid MEDLINE, Embase, Epistemonikos and the Cochrane Database of Systematic Reviews for systematic reviews investigating the effects of vitamin D fortification of food in general populations of any age. We used Cochrane methodology and assessed the methodological quality of included studies using AMSTAR (A MeaSurement Tool to Assess Systematic Reviews). We assessed the degree of overlap among reviews. All outcomes included in systematic reviews were assessed. The protocol is registered in PROSPERO (registration number: CRD42023420991). We included 27 systematic reviews out of 5028 records for analysis. Overall, 11 out of 12 systematic reviews calculating pooled estimates reported a significant increase in serum 25(OH)D concentrations. The mean change in serum 25(OH)D concentrations per additional 100 units of vitamin D ranged from 0.7 to 10.8 nmol/L. Fortification of food with vitamin D showed a reduction in the prevalence of vitamin D deficiency based on high-certainty evidence. Parathormone (PTH) levels were described to decrease, bone mineral density to increase, while the effects on other bone turnover markers were inconsistent. Fortification did not significantly impact most anthropometric parameters, but it seemed to positively influence lipid profiles. In summary, fortification of food with vitamin D results in a reduction of vitamin D deficiency and might increase serum 25(OH)D concentrations, to varying extents depending on the fortified vehicle and population characteristics. Additionally, fortification may have a positive impact on bone turnover and lipid metabolism but may only have a limited effect on anthropometric parameters.

show abstract