Association between frailty and hypoproteinaemia in older patients: meta-analysis and systematic review

Zhang, Linxue; Yang, Pingping; Yin, Furong; Zhang, Jinbo; Zhao, Benli; Zhou, Jiamei

doi:10.1186/s12877-024-05275-9

BMC Geriatr

2024

DOI: 10.1186/s12877-024-05275-9

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Association between frailty and hypoproteinaemia in older patients: meta-analysis and systematic review

Linxue Zhang,

Pingping Yang,

Furong Yin

et al.

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2024

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Cited by 1 publication

References 27 publications

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Frailty as a Risk Factor for Chronic Sinusitis: Insights from a Nationwide Cross‐sectional Survey

Chen,

Wang,

Zhang

et al. 2024

The Laryngoscope

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ObjectiveThis study aimed to investigate the connection between frailty and chronic rhinosinusitis (CRS) using a representative sample from the Korean population.MethodsThis cross‐sectional study included 24,269 participants initially, with data sourced from the Korean National Health and Nutrition Examination Survey (KNHANES) database. Frailty was assessed using the modified frailty phenotype (FP) and frailty index (FI), with criteria tailored for the KNHANES dataset. CRS was identified based on the self‐reported medical history of participants. Univariate and multivariate logistic regression analyses were employed to examine the correlation between CRS and frailty.ResultsThe prevalence of CRS among frail individuals was higher than that in the non‐frail group. Frailty status (assessed by FP) (odds ratio [OR] = 1.484, 95% confidence interval [CI]: 1.217, 1.809) and frailty status (assessed by FI) (OR = 1.571, 95% CI: 1.107, 2,230) were associated with an elevated risk of CRS, particularly in individuals aged 40–60 years (OR = 1.826, 95% CI: 1.245, 2.680) and ≥61 years (OR = 1.549, 95% CI: 1.067, 2.249), as well as those with an education level below high school (OR = 1.717, 95% CI: 1.124, 2.624). The heightened risk of CRS associated with frailty may be attributed to increased levels of slowness (OR = 1.606, 95% CI: 1.255, 2.054) and emotional exhaustion (OR = 1.363, 95% CI: 1.158, 1.604).ConclusionThis study supported a link between frailty and CRS, potentially induced by slowness and emotional exhaustion, suggesting that effective interventions for preventing frailty should be developed to manage CRS incidence.Level of EvidenceLevel 3 Laryngoscope, 2024

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Frailty as a Risk Factor for Chronic Sinusitis: Insights from a Nationwide Cross‐sectional Survey

Chen,

Wang,

Zhang

et al. 2024

The Laryngoscope

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Association between frailty and hypoproteinaemia in older patients: meta-analysis and systematic review

Cited by 1 publication

References 27 publications

Frailty as a Risk Factor for Chronic Sinusitis: Insights from a Nationwide Cross‐sectional Survey

Frailty as a Risk Factor for Chronic Sinusitis: Insights from a Nationwide Cross‐sectional Survey

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