Association between gastroesophageal reflux and dips in the oxygen transcutaneous saturation of the hemoglobin in infants with chronic obstructive ventilatory disease

Meyer, Ricardo; Fischer, Gilberto Bueno

doi:10.2223/jped.182

Cited by 1 publication

(1 citation statement)

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“…Reflux was considered when the intra-esophageal pH dropped below 4. The number of reflux, and long reflux episodes (longer than 5 min), duration of the longest reflux, total duration of reflux, percentage of time with reflux, reflux index (number of reflux episodes per h), esophageal clearance, DeMeester index, and the number of refluxes within 2 h after the meals (post-meal reflux) [9, 10] were measured. A DeMeester index less than 14.7 and a percentage of time with a pH < 4 less than 6.0% of the test (Lyon Consensus [11]) were considered normal.…”

Section: Methodsmentioning

confidence: 99%

Intra-Esophageal pH Monitoring on Two Consecutive Days in Patients With Gastroesophageal Reflux Symptoms

et al. 2019

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Background The best method to measure the frequency and duration of gastroesophageal reflux is 24-h pH or 24-h pH/impedance monitoring. However, the detection of reflux can vary when measured on different days. Our aim was to evaluate the possibility that the severity of gastroesophageal reflux is different even under similar conditions on two consecutive days. Methods We performed a 48-h pH monitoring in 12 subjects, aged 25 - 63 years, who complaint of heartburn and regurgitation, ten with esophagitis and two with non-erosive disease. The pH measurement was conducted at 5 cm from the lower esophageal sphincter. The patients stayed at the Clinical Investigation Ward of the hospital for 48 h. On each day, they consumed a 2,000 calorie diet. The results obtained on the first day were compared with those on the second day. Results Mean reflux index in the upright position was different between the two days. Results of the pH-monitoring within the 2 h after the meal revealed differences in the number of acidic reflux and reflux index episodes. Three patients had abnormal DeMeester score on one day and normal score on the other day. Considering the upper limit of 6.0% of the test duration with esophageal pH < 4 as indicative of gastroesophageal reflux disease, two patients showed abnormal results on one day and normal results on the other day. Conclusions The 24-h pH monitoring, performed on two consecutive days under similar conditions, can lead to different diagnosis of gastroesophageal reflux disease in symptomatic patients.

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Section: Methodsmentioning

confidence: 99%