Association between general and oral health-related quality of life in patients treated for oral cancer

Thapa

Health Qual Life Outcomes

2020

Background: Perceived dental health has shown to have a significant predictive effect on overall health perception and life satisfaction. Thus, it seems plausible that Health Related Quality of Life (HRQOL) measures are associated with Oral Health Related Quality of Life (OHRQOL) dimensions in Nepalese context as well. The adverse effects of tobacco on oral health are reported worldwide including Nepal. However, evidence which can quantify effects of tobacco smoking on dental health perception is limited. Thus, a study was designed to find association of smoking and socio demographic characteristics with OHRQOl and to determine association between OHRQOL and HRQOL among dental patients in Nepal. Methods: A cross sectional study was conducted among 125 current smokers and 125 non-smokers who attended oral surgery OPD of a teaching hospital in Kathmandu, Nepal. The study participants were enrolled through consecutive sampling and data was collected through a semi-structured questionnaire. The questionnaire consisted of questions related to sociodemographic characteristics, tobacco history, Oral Health Impacts Profile (OHIP)-14 and World Health Organization Quality of Life Brief version (WHOQOL-Bref) to assess OHRQOl and HRQOL respectively. Descriptive and inferential statistics were calculated by using SPSS version 18.0. The level of significance was set at 5%. Results: Among the socio demographic characteristics, patients with education of more than Class 12 had significantly higher average OHRQOL scores (p = 0.013) compared to illiterate patients. Current smokers reported significantly poorer scores in sub scales of psychological disability (p = 0.001), social disability (p = 0.003), physical pain (p < 0.001), functional limitation (p = 0.007) and also overall perceived oral health compared to nonsmokers. OHRQOL was significantly correlated with overall HRQOL in physical (p = 0.015) and psychological (p = 0.04) domains in this study sample. Conclusions: Improvements in OHRQOL may require a multidimensional approach with focus of social factors like education and behavioral factors like cigarette smoking. Also, improvement in OHRQOL might also lead to betterment of perceived overall health as they are interlinked.

Section: Correlation Between Ohrqol and Hrqolsupporting

confidence: 76%

Smoking, general and oral health related quality of life – a comparative study from Nepal

Thapa

Health Qual Life Outcomes

2020

“…The RAND SF-36 has a lack of disease-specific items; therefore, our study shows the advantage of combining the generic questionnaire on general health, the RAND SF-36, already utilized in EB populations (Tabolli et al, 2009), with the specific one related to the oral health, the OHIP-49, that has been validated and reliable in other oral-pharyngeal diseases (Lopez-Jornet et al, 2010;Barrios et al, 2015;Rimal et al, 2015), but has never been tested in patients with EB. The use of a generic and specific quality of life instrument has been suggested as the best option to better address the ongoing debate about whether generic or disease-specific instruments should be used (Streiner & Norman, 2003).…”

Section: Discussionmentioning

confidence: 90%

Oral Health-related Quality of Life in Patients with Dystrophic Epidermolysis Bullosa

Fortuna¹,

Aria²,

Whitmire³

et al. 2016

AJOM

Background: Dystrophic epidermolysis bullosa (DEB) is a devastating mucocutaneous inherited disorder that can have a remarkable impact on the oral cavity.Objective: To understand the relationships between oral health-related quality of life and general quality of life in DEB patients versus a control group.Methods: Twenty-eight DEB patients and 26 healthy individuals completed the following battery of scales: Oral Health Impact Profile (OHIP-49), the RAND Short Form-36 (SF-36), the Hamilton Rating Scale for anxiety (HAM-A) and depression (HAM-D).Results: All 7 dimensions in OHIP-49 demonstrated a statistically significant difference in functional limitations (Median:13.0; IQR:10.3-20.0 vs Median:7.0; IQR:2.0-9.0; p<0.001) and physical disability (Median:11.5; IQR:4.0-15.0 vs Median:0.0; IQR:0.0-2.3; p<0.001) in DEB patients vs controls, respectively. In RAND SF-36, physical functioning and general health were highly significant (p<0.001), whereas limitation due to physical health (p=0.043) and pain (p=0.010) were moderately significant. A positive correlation was found between oral health-related quality of life and anxiety (p=0.005 and p=0.03 in DEB patients and controls, respectively) and depression (p=0.045 and p=0.001 in DEB patients and controls, respectively). In 44 DEB patients, no correlation was found between general quality of life and anxiety and depression, oral health-related quality of life and oral-pharyngeal severity score, number of oral-pharyngeal sites involved and general quality of life, as well as oral health-related quality of life between patients with dominant and recessive DEB forms (p>0.05). Conclusions:The oral health-related quality of life is highly impaired in patients with DEB. General quality of life was affected only for some dimensions and was not significantly correlated with oral health-related quality of life.

“…In general, HRQoL and OHRQoL are closely related in generally healthy individuals, where OHRQoL can be seen as a subaspect of the whole HRQoL [ 35 ]. However, specific diseases might affect this relationship to an unclear extent [ 36 ]. Furthermore, HRQoL can also be directly associated with oral health conditions [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Does oral health-related quality of life of patients after solid organ transplantation indicate a response shift? Results of a systematic review

et al. 2020

Background The physical oral health and dental behaviour of patients after solid organ transplantation (SOT) has repeatedly been reported as insufficient. The objective of this systematic review was to detect whether the oral health-related quality of life (OHRQoL) of patients after SOT is reduced compared to that of healthy individuals. Methods A systematic literature search was performed by two independent individuals based on the PubMed, Web of Science and Scopus databases by using the following search terms: “transplantation” AND “oral health-related quality of life”. The findings were checked to determine eligibility, whereby publication prior to 31 October 2020, examination of adult patients (age at least 18 years) with SOT, reporting of an OHRQoL outcome and full text in English language were the prerequisites for inclusion in the qualitative analysis. Quality appraisal of the included studies was performed using the Agency for Healthcare Research and Quality methodology checklist. Results Seven of 25 studies that examined patients after kidney (3), heart (2), liver (1) and lung transplantation (1) were included. Four studies included healthy controls, and five studies included a cohort of patients before transplantation for comparison. Clinical oral health examinations were heterogeneous between groups. The majority of studies (5/7) applied the short form of the “Oral Health Impact Profile” (OHIP 14) to assess OHRQoL. The OHIP 14 values ranged between 1.7 and 8.9 across studies, indicating an unaffected or just slightly reduced OHRQoL. Only one study found better OHRQoL in patients after SOT compared to a group before SOT, and one study confirmed worse OHRQoL of SOT recipients compared to a healthy control. Only two studies revealed an association between OHRQoL and oral health parameters. Furthermore, two studies each found a relationship between OHRQoL and general health-related quality of life or disease-related parameters. Conclusions Patients after SOT show an unaffected or only slightly reduced OHRQoL, which was mainly independent of the insufficient oral status. This might indicate a shift in the perception threshold for oral diseases and conditions caused by the general health burden related to the SOT.