Association Between Genetic Polymorphism of Milk Proteins and Production Traits During Three Lactations

Ng-Kwai-Hang, K.F.; Monardes, H.G.; Hayes, J. F.

doi:10.3168/jds.s0022-0302(90)79038-8

Cited by 83 publications

(58 citation statements)

References 17 publications

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“…The CA 2 B was found mainly in autochthonous Nordic breeds and BA 2 A was predominant in the highly selected commercial dairy breeds like Finnish Ayshire or Holstein-Friesian. Other studies [24,34] have found positive effects of CSN1S1*B on the milk yields of dairy cows and [45] describe a positive effect of BA 2 A on milk yield in one of four examined grandsire families in the Finnish Ayrshire. Our results show that geographic patterns of haplotype distributions follow frequency trends of alleles at CSN1S1 (CSN1S1*B: P ≤ 0.010) and CSN3 (CSN3*A: P ≤ 0.00) along the latitude with highest frequencies for the yield related alleles CSN1S1*B and CSN3*A in north western Europe.…”

Section: Discussionmentioning

confidence: 88%

Geographic distribution of haplotype diversity at the bovine casein locus

et al. 2004

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-The genetic diversity of the casein locus in cattle was studied on the basis of haplotype analysis. Consideration of recently described genetic variants of the casein genes which to date have not been the subject of diversity studies, allowed the identification of new haplotypes. Genotyping of 30 cattle breeds from four continents revealed a geographically associated distribution of haplotypes, mainly defined by frequencies of alleles at CSN1S1 and CSN3. The genetic diversity within taurine breeds in Europe was found to decrease significantly from the south to the north and from the east to the west. Such geographic patterns of cattle genetic variation at the casein locus may be a result of the domestication process of modern cattle as well as geographically differentiated natural or artificial selection. The comparison of African Bos taurus and Bos indicus breeds allowed the identification of several Bos indicus specific haplotypes (CSN1S1*C-CSN2*A 2 -CSN3*A I / CSN3*H) that are not found in pure taurine breeds. The occurrence of such haplotypes in southern European breeds also suggests that an introgression of indicine genes into taurine breeds could have contributed to the distribution of the genetic variation observed.casein / haplotype / Bos taurus / Bos indicus / phylogeny

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Section: Discussionmentioning

confidence: 88%

Geographic distribution of haplotype diversity at the bovine casein locus

et al. 2004

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“…Usually, these relationships depend on cattle breeds and the country of origin. Some studies claim that the BB genotype was associated with higher (Van Eenennaam & Medrano, 1991) or lower (Bovenhuis et al, 1992) milk yield whereas other studies indicated no effect (Ng-Kwai-Hang et al, 1990;Lundén et al, 1997). The present results support data by Bovenhuis et al (1992) suggesting a 15% decrease of the milk production of the BB homozygous animals compared to the AB heterozygous cows.…”

Section: Csn3 Gene Polymorphismmentioning

confidence: 99%

Application of Milk Proteins Genetic Polymorphism for Selection and Breeding of Dairy Cows in Bulgaria

Hristov¹,

Teofanova²,

Mehandzhiyski³

et al. 2012

Milk Production - Advanced Genetic Traits, Cellular Mechanism, Animal Management and Health

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“…The other alleles are rare in other breeds that have been studied. It has been postulated that CSN1S1*B has positive effects on milk yield (LIN et al, 1986), whereas higher milk protein content is found in animal heterozygous for CSN1S1*BC compared to BB homozygous animals (NG- KWAI-HANG et al, 1990;ALEANDRI et al, 1990, BOVENHUIS et al, 1992. In Nordic cattle breeds LIEN et al (1999) identified an allele frequency gradient with low frequency of CSN1S1*B in native breeds to high frequency of CSN1S1*B and loss of CSN1S1*C in high selected dairy cattle.…”

Section: Introductionmentioning

confidence: 99%

Intragenic haplotypes at the bovine <i>CSN1S1</i> locus

et al. 2002

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SummaryA new alternative genotyping method based on PCR-SSCP was developed for direct differentiation of the CSN1S1 alleles B and C in the coding region. In addition a PCR-RFLP test based on a MaeIII restriction site in the promoter region of CSN1S1, reported in the literature as an alternative test for the differentiation of CSN1S1*B and C was used and the alleles named b and c. Genotyping of 649 animals belonging to 17 European and Turkish cattle breeds showed differences in occurrence and frequency of the alleles.

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Association Between Genetic Polymorphism of Milk Proteins and Production Traits During Three Lactations

Cited by 83 publications

References 17 publications

Geographic distribution of haplotype diversity at the bovine casein locus

Geographic distribution of haplotype diversity at the bovine casein locus

Application of Milk Proteins Genetic Polymorphism for Selection and Breeding of Dairy Cows in Bulgaria

Intragenic haplotypes at the bovine <i>CSN1S1</i> locus

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Association Between Genetic Polymorphism of Milk Proteins and Production Traits During Three Lactations

Cited by 83 publications

References 17 publications

Geographic distribution of haplotype diversity at the bovine casein locus

Geographic distribution of haplotype diversity at the bovine casein locus

Application of Milk Proteins Genetic Polymorphism for Selection and Breeding of Dairy Cows in Bulgaria

Intragenic haplotypes at the bovine &lt;i&gt;CSN1S1&lt;/i&gt; locus

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Intragenic haplotypes at the bovine <i>CSN1S1</i> locus