2008
DOI: 10.1097/mcg.0b013e31806daf64
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Association Between GERD-related Erosive Esophagitis and Obesity

Abstract: Obesity, especially abdominal obesity, was the significant risk factor for erosive esophagitis.

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Cited by 47 publications
(31 citation statements)
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“…In our study, the prevalence of RE in COPD was 30%, which is higher than that reported previously in the Korean general population (Table 6) [19,20,21,22] and Asia [23]. Generally, the prevalence of GERD in Asia is known to be lower than that in Western countries [17,23].…”
Section: Discussioncontrasting
confidence: 65%
“…In our study, the prevalence of RE in COPD was 30%, which is higher than that reported previously in the Korean general population (Table 6) [19,20,21,22] and Asia [23]. Generally, the prevalence of GERD in Asia is known to be lower than that in Western countries [17,23].…”
Section: Discussioncontrasting
confidence: 65%
“…The biologic mechanism between BMI-GERD association has not been clearly identified; however, 1 potential mechanism is related to mechanical factors. 5 The pattern of obesity may be more important than BMI, 41,42 and abdominal obesity leads to an increase in abdominal pressure, 43 increased frequency of transient lower esophageal sphincter relaxation, 44 and/or the formation of hiatus hernia. 45 In addition, the presence of H. pylori has been suggested to protect against the development of GERD by suppressing gastric acidity via the neutralizing effect of bacterial ammonia production and corpus gastritis induced by persistent H. pylori infection.…”
Section: Discussionmentioning
confidence: 98%
“…Obese adults are significantly more likely to suffer from gastroesophageal reflux disease (GERD) than patients of normal weight. The incidence of GERD in obese patients can be as high as 58%, nearly three times more likely than patients with normal body mass index (BMI) [2][3][4][5][6][7]. In addition, obese adults with GERD typically exhibit more severe symptoms and are more likely to have esophagitis [8].…”
Section: Introductionmentioning
confidence: 99%