Association between headache and temporomandibular disorder

Abouelhuda, Amira Mokhtar; Kim, SangYun; Kim, Young Kyun

doi:10.5125/jkaoms.2017.43.6.363

Cited by 10 publications

(7 citation statements)

References 28 publications

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“…SB may be associated with TMDs, and headache is often an accompanying symptom (33). Wagner et al have showed an association between headache and TMDs ( p < 0.001) and between headache and anxiety ( p = 0.002), but not between headache and bruxism ( p = 0.670) (17).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Relationship Between Sleep Bruxism and Headache Impact Test-6 (HIT-6) Scores: A Polysomnographic Study

et al. 2019

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Sleep bruxism (SB) is a masticatory muscle activity during sleep characterized by teeth clenching or grinding and/or bracing or thrusting of the mandible. Morning headache is considered as a common symptom of SB; however, the relationship between SB and headache and its impact on patient's life is not clear. Therefore, the present study aimed to assess the relationship between SB using polysomnography with video/audio recording and Headache Impact Test-6 (HIT-6) scores. SB was evaluated in respondents by single-night diagnostic polysomnography with video/audio recording. The study found that Bruxism Episode Index was similar in the group with significant impact of headache on patient's life (HIT-6 score ≥ 50) and in group with little or no impact (HIT-6 score < 50). A statistically significant positive correlation was observed between bruxism associated with arousal and HIT-6 score ( r = 0.51, p < 0.05) and between mixed bruxism and HIT-6 score ( r = 0.58, p < 0.05) in the subgroup with phasic bruxism. The results indicated the relationship between SB and impact of severity of headache on the patient's life measured by HIT-6 is only modest. It was also found that the impact of severity of headache measured by HIT-6 is altered only in those with phasic bruxism and is associated with arousal. Further research should elucidate the factors influencing the relationship between SB and headache. Trial Registration: Clinical Trials NCT03083405, WMU1/2017, https://clinicaltrials.gov/ct2/show/NCT03083405

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Section: Discussionmentioning

confidence: 99%

Evaluation of Relationship Between Sleep Bruxism and Headache Impact Test-6 (HIT-6) Scores: A Polysomnographic Study

et al. 2019

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“…Temporomandibular joint disorder has been reported by service members and veterans with exposure to IEDs and blast injury (98) and posttraumatic stress disorder (PTSD) (99). Of relevance to the data presented, headaches are the most commonly reported condition associated with temporomandibular joint disorders (100). Veterans with blast mTBI report high prevalence of chronic daily headaches and migraines, as compared to the general population with TBI and concussion (101)(102)(103).…”

Section: Headache and Chronic Painmentioning

confidence: 90%

DNA Methylation Patterns of Chronic Explosive Breaching in U.S. Military Warfighters

Wang

Wilson

et al. 2020

Front. Neurol.

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Background: Injuries from exposure to explosions rose dramatically during the Iraq and Afghanistan wars, which motivated investigation of blast-related neurotrauma. We have undertaken human studies involving military "breachers"-exposed to controlled, low-level blast during a 3-days explosive breaching course. Methods: We screened epigenetic profiles in peripheral blood samples from 59 subjects (in two separate U.S. Military training sessions) using Infinium MethylationEPIC BeadChips. Participants had varying numbers of exposures to blast over their military careers (empirically defined as high ≥ 40, and conversely, low < 39 breaching exposures). Daily self-reported physiological symptoms were recorded. Tinnitus, memory problems, headaches, and sleep disturbances are most frequently reported. Results: We identified 14 significantly differentially methylated regions (DMRs) within genes associated with cumulative blast exposure in participants with high relative to low cumulative blast exposure. Notably, NTSR1 and SPON1 were significantly differentially methylated in high relative to low blast exposed groups, suggesting that sleep dysregulation may be altered in response to chronic cumulative blast exposure. In comparing lifetime blast exposure at baseline (prior to exposure in current training), and top associated symptoms, we identified significant DMRs associated with tinnitus, sleep difficulties, and headache. Notably, we identified KCNN3, SOD3, MUC4, GALR1, and WDR45B, which are implicated in auditory function, as differentially methylated associated with self-reported tinnitus. These findings suggest neurobiological mechanisms behind auditory injuries in our military warfighters and are particularly relevant given tinnitus is not only a primary disability among veterans, but has also been demonstrated in active duty medical records for populations exposed to blast in training. Additionally, we found that differentially methylated regions associated with the genes CCDC68 and COMT track with sleep difficulties, and those within FMOD and TNXB track with pain and headache. Conclusion: Sleep disturbances, as well as tinnitus and chronic pain, are widely reported in U.S. military service members and veterans. As we have previously demonstrated, DNA methylation encapsulates lifetime exposure to blast. The current Wang et al. Methylation Pattern of Cumulative Blast data support previous findings and recapitulate transcriptional regulatory alterations in genes involved in sleep, auditory function, and pain. These data uncovered novel epigenetic and transcriptional regulatory mechanism underlying the etiological basis of these symptoms.

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“…Abouelhuda et al 20 in their practical experience and a review of the literature suggested that headache increases the frequency and intensity of pain parameters, complicating TMD in both diagnostic and treatment phases. Therefore, early and multidisciplinary treatment of TMDs is necessary to avoid overlap of painful events that could become chronic.…”

Section: Discussionmentioning

confidence: 99%

Mischievous mandibular third molars camouflaging temporomandibular joint disorders

Bhardwaj

Gupta

Narula

2022

JKAOMS

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Objectives: The aim of this study was to observe the relationship between impacted mandibular third molars and development of temporomandibular joint (TMJ) disorders. Knowledge of the factors that have an adverse effect on the TMJ is necessary for proper diagnosis, treatment, and prognosis of TMJ disorders. Materials and Methods: The study was performed on 80 patients aged between 20 and 60 years with impacted mandibular third molars, over a period of two months. The patients were examined clinically and radiologically to determine the type of impaction and detect the associated TMJ symptoms or disorders. Results: In the 80 patients, 63.8% (51/80) of TMJ disorders were found in the horizontal group, 46.3% (37/80) in the mesioangular group, 42.5% (34/80) in the distoangular group, and 30.0% (24/80) in the vertical group of impacted mandibular third molars. Conclusion:The study concluded that type of impacted mandibular third molar is factor in the development of temporomandibular disorders.

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Association between headache and temporomandibular disorder

Cited by 10 publications

References 28 publications

Evaluation of Relationship Between Sleep Bruxism and Headache Impact Test-6 (HIT-6) Scores: A Polysomnographic Study

Evaluation of Relationship Between Sleep Bruxism and Headache Impact Test-6 (HIT-6) Scores: A Polysomnographic Study

DNA Methylation Patterns of Chronic Explosive Breaching in U.S. Military Warfighters

Mischievous mandibular third molars camouflaging temporomandibular joint disorders

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