Association between high systolic blood pressure and objective hearing impairment among Japanese adults: a facility-based retrospective cohort study

Miyata, Jun; Umesawa, Mitsumasa; Yoshioka, Tetsuya; Iso, Hiroyasu

doi:10.1038/s41440-021-00737-8

Cited by 18 publications

(28 citation statements)

References 33 publications

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“…Although many researchers have investigated the link between hypertension and hearing loss [4,11]; the underlying mechanism has not been found. The blood labyrinthine barrier (BLB) is a barrier between the vasculature and the inner ear fluids (endolymph and perilymph) [11,28]. Hypertension may alter the permeability of the BLB and have an effect on the osmotic pressure between endolymph and perilymph.…”

Section: The Results Of the Present Research Are Consistent With Prev...mentioning

confidence: 99%

“…According to a systematic review, there is broad evidence of an association between tinnitus and arterial hypertension [8]. One study found an association between tinnitus and arterial hypertension which was particularly strong in older patients [14], complementary to a study in China which evaluated the relationship between hypertension and hearing disorders of the elderly [11]. Auditory thresholds increased gradually in proportion with age, especially in hypertensive patients.…”

Section: Discussionmentioning

confidence: 99%

“…As blood pressure increases, the level of hearing diminishes [2,4,5,7,8]. Several authors have investigated the risk factors of hypertension and hearing loss [2,4,5,[9][10][11][12][13][14]. Bao et al determined that increases in long-term blood pressure were related to hearing loss [12], and there are several reports that hearing impairment can impact even the simplest functions of daily life [2][3][4][5][6][7]13,14].…”

Section: Introductionmentioning

confidence: 99%

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Factors Increasing the Risk of Hearing Loss Among Hypertensive Patients: A Prospective Study

Bener¹,

Barışık²,

İnan³

2022

J Hear Sci

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Background: Hearing loss and hypertension are leading causes of disability, affecting over 360 million people. The aim of this study was to assess the impacts of factors such as vitamin D and sleep disorder on the risk of hearing loss among hypertensive patients. Material and methods:This prospective cohort study involved 885 patients aged between 25 and 65 years old who visited our ENT and Endocrinology departments. The study was based on biochemical tests, physical examination, hearing assessment, and Pittsburgh Sleep Quality Index test. Statistical analysis used bivariate and multivariate stepwise regression.Results: Of 855 hypertensive patients, 184 (21.5%) had hearing loss. There were statistically significant differences between hypertensive patients with and without hearing loss in terms of BMI, smoking, family history of diabetes, tinnitus, vertigo, and headache. Moreover, there were statistically significant differences between hypertensive patients with hearing loss versus those with normal hearing in terms of vitamin D, calcium, magnesium, potassium, fasting glucose, HbA1C, HDL, systolic and diastolic blood pressure, microalbuminuria, and sleep quality. Among hypertensive patients, a multivariate regression analysis (stepwise method) indicated that vertigo, systolic blood pressure, vitamin D deficiency, numbness in the hand, tinnitus, vigorous activity, metabolic syndrome, sleep disturbance, and obesity were all risk predictors of hearing loss. Conclusions:Controlling hypertension, vitamin D level, sleep, and lifestyle might lower the risk of hearing loss among hypertensive patients.

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Section: The Results Of the Present Research Are Consistent With Prev...mentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Factors Increasing the Risk of Hearing Loss Among Hypertensive Patients: A Prospective Study

Bener¹,

Barışık²,

İnan³

2022

J Hear Sci

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“…Around 360 million people (over 5%) all over the world live with this disability (disabling hearing loss), which makes hearing loss a factor that is responsible for years lived with a disability [ 1 , 2 ]. Among the six World Health Organization (WHO) regions, the highest prevalence of hearing loss is in the western Pacific region (with 136.5 million people), followed by Southeast Asia (with 109.5 million people) [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…However, the molecular mechanism behind this association is still under investigation, and it could be due to vascular injury [ 18 , 19 ]. A recent cohort study investigating hearing loss and blood pressure was conducted in Japanese adults, and those findings suggested that a higher SBP condition was a significant risk factor for hearing loss at 1 kHz [ 3 ]. A long time ago, the crucial role of SBP was already mentioned in the Framingham Heart study which determined that SBP had a larger capacity in the future risk of cardiovascular disease than diastolic blood pressure (DBP) [ 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Hearing Problems in Indonesia: Attention to Hypertensive Adults

Fitriana

Bai²

2022

IJERPH

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Known as a silent disability, hearing loss is one of the major health burdens worldwide. Evidence implies that those suffering from hypertension can experience hearing disturbances. Self-reporting of hearing problems and self-reporting of hypertension may be useful in providing an alarm for detecting hearing problems. However, in the Indonesian population, this matter has not been properly reported. The aim of this study was to explore the prevalence of hearing problems and their relationships with other demographic factors. In total, 28,297 respondents of productive age from the Indonesian Family Life Survey 5th wave were assessed. A questionnaire and physical examination data were included in this survey. Self-reported hearing problems and their predictors were analyzed using univariate and multivariate logistic regressions. Hypertension awareness was a significant predictor of having a hearing problem (odds ratio (OR) [95% confidence interval (CI)], p value: 2.715 [1.948~3.785], <0.001). Having a general check-up was also crucial for detecting hearing problems (2.192 [1.54~3.121], <0.001). There was a significant link between hearing problems and early adults who have isolated systolic hypertension. Hypertension awareness and having a general check-up had predictive value for detecting hearing problems in adults in the age range of 26~35 years. Therefore, public health strategies for hearing loss prevention might target this group by detecting and treating hypertension.

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Machine Learning Prediction of Objective Hearing Loss With Demographics, Clinical Factors, and Subjective Hearing Status

Gathman

Choi

Vasdev

et al. 2023

Otolaryngol.--head neck surg.

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ObjectiveHearing loss (HL) is highly prevalent, yet underrecognized and underdiagnosed. Lack of standardized screening, awareness, cost, and access to hearing testing present barriers to HL identification. To facilitate prescreening and selection of patients who warrant audiometric evaluation, we developed a machine learning (ML) model to predict speech‐frequency pure‐tone average (PTA).Study DesignCross‐sectional study.SettingNational Health and Nutrition Examination Survey (NHANES).MethodsThe cohort included 8918 adults (≥20 years) who completed audiometric testing with NHANES (2012‐2018). The primary outcome measure was the prediction of better hearing ear speech‐frequency PTA. Relevant predictors included demographics, medical conditions, and subjective assessment of hearing. Supervised ML with a tree‐based architecture was used. Regression performance was determined by the mean absolute error (MAE) with binary classification assessed with area under the receiver operating characteristic curve (AUC).ResultsUsing the full set of predictors, the test set MAE between the ML‐predicted and actual PTA was 5.29 dB HL (95% confidence interval [CI]: 4.97‐5.61). The 5 most influential predictors of higher PTA were increased age, worse subjective hearing, male gender, increased body mass index, and history of smoking. The 5‐factor abbreviated model performed comparably to the extended feature set with MAE 5.36 (95% CI: 5.03‐5.69) and AUC for PTA > 25 dB HL of 0.92 (95% CI: 0.90‐0.94).ConclusionThe ML model was able to predict PTA with patient demographics, clinical factors, and subjective hearing status. ML‐based prediction may be used to identify individuals who could benefit most from audiometric evaluation.

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Association between high systolic blood pressure and objective hearing impairment among Japanese adults: a facility-based retrospective cohort study

Cited by 18 publications

References 33 publications

Factors Increasing the Risk of Hearing Loss Among Hypertensive Patients: A Prospective Study

Factors Increasing the Risk of Hearing Loss Among Hypertensive Patients: A Prospective Study

Hearing Problems in Indonesia: Attention to Hypertensive Adults

Machine Learning Prediction of Objective Hearing Loss With Demographics, Clinical Factors, and Subjective Hearing Status

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