2024
DOI: 10.3389/fneur.2024.1386844
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Association between human blood metabolites and cerebral cortex architecture: evidence from a Mendelian randomization study

Zongzhi Jiang,
Yining Sun,
Songyan Liu

Abstract: BackgroundDysregulation of circulating metabolites may affect brain function and cognition, associated with alterations in the cerebral cortex architecture. However, the exact cause remains unclear. This study aimed to determine the causal effect of circulating metabolites on the cerebral cortex architecture.MethodsThis study utilized retrieved data from genome-wide association studies to investigate the relationship between blood metabolites and cortical architecture. A total of 1,091 metabolites and 309 meta… Show more

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