Association Between Hypertension and Coronary Artery Disease as Assessed by Coronary Computed Tomography

Abstract

Multidetector row computed tomography (MDCT) enables the accurate noninvasive assessment of coronary artery stenosis and plaque imaging. The characteristics of patients who have coronary artery disease (CAD) as assessed by MDCT coronary computed tomography (CT) are not well known. Participants consisted of 513 consecutive patients with suspected CAD who underwent coronary CT. The authors quantified patient characteristics, including the prevalence of hypertension (HTN), hyperlipidemia and diabetes mellitus (DM), visceral fat area (VFA) and subcutaneous fat area using CT, and plasma levels of metabolic factors, including adiponectin and leptin. Although plasma levels of adiponectin in men and leptin in women were significantly associated with chronic kidney disease, there were no differences in these levels between patients with and without CAD. HTN was most significantly associated with the presence of CAD by multivariate logistic regression analysis (men, P=.002; women, P=.048). Finally, the percentage of CAD significantly increased as systolic blood pressure increased (trend, P=.0002) in men but not women. In conclusion, hypertension was significantly associated with CAD as assessed by coronary CT. J Clin Hypertens (Greenwich). 2011;13:198–204. © 2010 Wiley Periodicals, Inc.

Three-Dimensional Reconstruction of Coronary Arteries and Its Application in Localization of Coronary Artery Segments Corresponding to Myocardial Segments Identified by Transthoracic Echocardiography

“…Computed tomography angiography (CTA) of the coronary arteries has been shown to clearly display the trunk and branches of the coronary arteries, particularly the trunk of the main coronary artery, the proximal segment of the right coronary artery, the proximal segment of the anterior descending branch, and the proximal segment of the left circumflex branch [10, 11]. CTA is less effective than CAG in displaying the distal segment of the right coronary artery, the distal segment of the left anterior descending branch, and the distal segment of the circumflex branch.…”

Effect of Metabolic Components on the Incidence of Cerebrovascular/Cardiovascular Disease Among Male Workers in Japan: 3‐Year Follow‐Up Study

“…In contrast, there was no significant contribution of increased waist circumference, increased fasting glucose, increased triglyceride, and decreased high-density-lipoprotein cholesterol ( Using data from a 3-year follow-up study in the workplace, increased blood pressure in men significantly contributed to the incidence of cerebrovascular ⁄ cardiovascular disease in concordance with reports by Mitsutake and associates. 1 In addition, there was no significant contribution of waist circumference on the incidence of cerebrovascular ⁄ cardiovascular disease as Mitsutake and coworkers 1 and Furukawa and colleagues 3 separately pointed out.…”

“…Mitsutake and colleauges 1 conducted a cross‐sectional clinical study and concluded that hypertension is significantly associated with coronary artery disease (CAD) as assessed by coronary computed tomography (CT). They first recognized that age and the metabolic syndrome are both significantly associated with CAD, and then several metabolic components such as hypertension, dyslipidemia, diabetes, and visceral fat were used as independent variables to analyze the relationship with CAD.…”

A Coronary Artery Calcium Score of Zero in Patients Who Have Undergone Coronary Computed Tomography Angiography Is Associated With Freedom From Major Adverse Cardiovascular Events

“…We evaluated coronary stenosis using CCTA as previously described [6][7][8][9][10][11]. Patients were assessed by 64-multidetector computed tomography (MDCT) on an Aquilion 64 (TOSHI-BA, Tokyo, Japan) or 320-MDCT on an Aquilion ONE Vi-SION (TOSHIBA, Tokyo, Japan).…”

“…Thus, CACS is a good marker of future CVD risk. We have been studying the CCTA Registry at Fukuoka University in Japan (FU-CCTA Registry) and identified CVD risk factors for the primary prevention of CAD [6][7][8][9][10][11]. Using the FU-CCTA Registry, we determined the association between CACS and the prognosis in patients who underwent CCTA.…”