Association betweenHelicobacter pyloriInfection and Occurrence of Anemia among Pregnant Women Attending Antenatal Care in Kulito Health Center, Halaba Zone, South Ethiopia, 2018

Abstract

Background. Anemia in pregnancy is defined as a hemoglobin (Hb) concentration of less than 11 grams (gm)/deciliter (dl) in venous blood. Globally, it affects 1.62 billion people. In developing countries, anemia is a major cause of maternal and child morbidity and mortality. Globally, anemia contributes to 20% of all maternal deaths. Nearly 50% of the world’s population is estimated to be infected with Helicobacter pylori (HP). High prevalence of HP among pregnant women was also reported in developing countries than developed ones. The association between HP infection and occurrence of anemia is not well known in Ethiopia. Therefore, the aim of this study was to determine the association between anemia and Helicobacter pylori infection among pregnant women attending antenatal care follow-up in Kulito Health Center, Halaba Zone, South Ethiopia. Methods. Institution-based cross-sectional study was employed. Systematic random sampling procedure was employed to select 236 pregnant women who attended antenatal care at Kulito Health Center. An interviewer-administered questionnaire supplemented by laboratory tests was used to obtain the data. The collected data were analyzed by using SPSS version 20.0. Results. The prevalence of anemia among antenatal care attendant pregnant women of Kulito Health Center was 27.5% with 36 (15.2%) of mild, 29 (12.3%) of moderate, and no severe cases of anemia. The overall prevalence of HP infection among study participants was found to be 129 (54.7%) (95% CI: 47.9–61.4). Factors significantly associated with anemia were presence of HP infection (AOR = 3.064, 95% CI: 1.336 7.027), low interpregnancy gap (AOR = 2.863, 95% CI: 1.245–6.582), being on the third trimester (AOR = 6.457; 95% CI: 1.276–32.729), and mid-upper arm circumference (MUAC) level <21 cm (AOR = 2.595, 95% CI: 1.044–6.450). Conclusion. This study revealed that anemia and HP infection were highly prevalent among pregnant women attending the antenatal follow-up clinic in Kulito Health Center. HP infection, low interpregnancy gap, being on the third trimester, and MUAC less than 21 cm were the independent factors associated with anemia. Recommendation. Pregnant women should be aware that anemia is a problem that can be prevented by early prevention and treatment of HP infection and undernutrition, using family planning to widen the interpregnancy gap. Further experimental studies are warranted to determine the cause and effect of the association between anemia and HP infection.

Helicobacter pylori infection and related factors among pregnant women at Debre Tabor General Hospital, Northwest Ethiopia, 2021

“…The nding of this study is in line with the study conducted in France (32), A Systematic Review and Metaanalysis Study did in Global prevalence (3) The prevalence of this study which is higher than the prevalence of previous studies conducted in the Hispanic population (39), As compared to other previous studies, the prevalence of the current study is much lower than a study conducted in different parts of Ethiopia (5,10,19,(40)(41)(42)(43) a meta-analysis study in Iran (44), in Rural Durango, Mexico (34), Ilam, Iran(3), in Uganda(6), in Kawempe Health Centre Kampala, the capital city of Uganda ( 14), Alexandria University, Egypt(2) in Sudan (45), South of Libya (39), University of Maiduguri Teaching Hospital Borno State Nigeria (22) in Sant'Anna Hospital of Turin, Italy(36), in Netherland(…”

“…When the uptake of iron by Helicobacter pylori for growth does not occur, increased availability of iron in lactoferrin in the gastric mucosa and the absorption of iron is not affected. On the other hand, bacterium host competition does not occur for dietary iron supply (14,41,47).…”

Barriers to Health Workers in Iron Deficiency Anemia Prevention among Indonesian Pregnant Women

“…Iron deficiency is the commonest nutritional problem causing anemia among pregnant women [ 10 ]. Half of all the cases of anemia can be attributed to iron deficiency [ 11 ]. Iron deficiency anemia (IDA) during pregnancy is associated with adverse health effects, including low birth weight and preterm birth.…”

Nutritional factors for anemia in pregnancy: A systematic review with meta-analysis

“…In addition, iron deficiency is considered to be the most common cause of anemia in pregnancy, therefore, most studies recommend that pregnant women should take adequate iron supplements to prevent anemia in pregnancy (11,12). On the contrary, some studies have shown that iron supplementation did not reduce the incidence of anemia in pregnancy (13,14). Some studies have even concluded that even without iron supplementation during pregnancy, the incidence of anemia in pregnant women is not significantly higher (15).…”