2021
DOI: 10.1016/j.bja.2021.06.024
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Association between intraoperative mean arterial pressure and postoperative complications is independent of cardiac index in patients undergoing noncardiac surgery

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Cited by 10 publications
(15 citation statements)
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“…These treatment algorithms first optimize stroke volume with fluid boluses and then, if hypotension persists, add a vasopressor to maintain MBP > 65 mmHg. This management reflects the increasing evidence that perioperative hypotension is associated with harm and should be avoided [ 294 , 296 , 297 ].…”
Section: Perioperative Interventionsmentioning
confidence: 93%
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“…These treatment algorithms first optimize stroke volume with fluid boluses and then, if hypotension persists, add a vasopressor to maintain MBP > 65 mmHg. This management reflects the increasing evidence that perioperative hypotension is associated with harm and should be avoided [ 294 , 296 , 297 ].…”
Section: Perioperative Interventionsmentioning
confidence: 93%
“…Approximately one-third of these hypotensive events occurred before the surgical incision. There is increasing evidence from large retrospective database reviews showing that even a short duration of hypotension is associated with myocardial injury and acute kidney injury [293][294][295] and that the severity of injury is associated with both the duration and degree of hypotension [294,296]. One major prospective interventional trial showed a significant reduction in complications (38% versus 51%, p = 0.02) with individualized blood pressure management (n = 147) compared with standard pressure management (n = 245) [297].…”
Section: Intraoperative Hypotension Should Be Avoided As Even Short D...mentioning
confidence: 99%
“…This management reflects the increasing evidence that perioperative hypotension is associated with harm and should be avoided. 294 , 296 , 297 …”
Section: Perioperative Interventionsmentioning
confidence: 99%
“…There is increasing evidence from large retrospective database reviews showing that even a short duration of hypotension is associated with myocardial injury and AKI [293][294][295] and that the severity of injury is associated with both the duration and degree of hypotension. 294,296 One major prospective interventional trial showed a significant reduction in complications (38% versus 51%; p = 0.02) with individualized blood pressure management (n = 147) compared with standard pressure management (n = 245). 297 In this study, patients in the intervention group had their fluid status optimized and then had a vasopressor infused to maintain their systolic blood pressure within 10% of their resting blood pressure.…”
Section: Intraoperative Hypotension Should Be Avoided As Even Short D...mentioning
confidence: 99%
“…101 However a recent sub-analysis of the CrystalloideColloid Study found that the worse outcomes associated with hypotension were independent of cardiac index in noncardiac surgery patients. 102…”
Section: Importance Of Cardiac Output To Organ Perfusionmentioning
confidence: 99%