Association Between IVUS Findings and Adverse Outcomes in Patients With Coronary Artery Disease

Calvert, Patrick A.; Obaid, Daniel R.; O’Sullivan, Michael; Shapiro, Leonard M.; McNab, Duncan; Densem, Cameron G.; Schofield, Peter M.; Braganza, Denise; Clarke, Sarah; Ray, Kausik K.; West, Nick E.J.; Bennett, Martin R.

doi:10.1016/j.jcmg.2011.05.005

Cited by 457 publications

(273 citation statements)

References 11 publications

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“…25 To obtain greater accuracy, the use of contrast-enhanced ultrasonography, highresolution MR imaging, multidetector CT, and concurrent VH-IVUS may be required. 2,26,27 VIVA (VH-IVUS in Vulnerable Atherosclerosis) 28 and PROSPECT (Providing Regional Observations to Study Predictors of Events in the Coronary Tree) 29 are 2 prospective studies that demonstrated that VH-IVUS can reliably identify the atherosclerotic plaques that are at increased risk of major adverse cardiac events. The unique features of intracranial vessels prevent extrapolation of current data regarding plaque characterization by use of different imaging modalities in extracranial vessels.…”

Section: Discussionmentioning

confidence: 99%

Intracranial-Derived Atherosclerosis Assessment: An In Vitro Comparison between Virtual Histology by Intravascular Ultrasonography, 7T MRI, and Histopathologic Findings

Majidi

Sein

Watanabe

et al. 2013

AJNR Am J Neuroradiol

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Section: Discussionmentioning

confidence: 99%

Intracranial-Derived Atherosclerosis Assessment: An In Vitro Comparison between Virtual Histology by Intravascular Ultrasonography, 7T MRI, and Histopathologic Findings

Majidi

Sein

Watanabe

et al. 2013

AJNR Am J Neuroradiol

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“…Studies have shown a high degree of correlation between OCT imaging and fibrous cap thickness on histologic evaluation. 1,17,23 In addition, OCT can identify TCFA by measuring the thickness of the fibrous cap and the arc of the lipid-rich plaque. [24][25][26] Lipid pools are less sharply delineated than calcification and show lower signal intensity.…”

Section: Plaque Characterisationmentioning

confidence: 99%

Intravascular Ultrasound Versus Optical Coherence Tomography for Coronary Artery Imaging – Apples and Oranges?

Rathod¹,

Hamshere²,

Jones³

et al. 2015

Interventional Cardiology Review

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Coronary angiography has been the gold standard technique for evaluating coronary arterial disease for the past 50 years. Increasingly, however, realisation of the limitations of coronary angiography, mainly the inability to supply information regarding the coronary wall, has prompted the design and development of adjunctive technologies to better evaluate not just luminal disease but also the burden and character of atherosclerotic plaque within the vessel. The development of intracoronary imaging modalities, namely intravascular ultrasound (IVUS) and optical coherence tomography (OCT), has progressed quickly and these technologies now have established roles in the diagnosis and treatment of coronary artery disease. In general, intracoronary devices that can assess the coronary endothelium use either acoustic or optical signals that are received by a coronary catheter (IVUS uses ultrasound, OCT uses near-infrared light).This review addresses these two widely used intracoronary imaging techniques, looking at their clinical applications, recent evidence for their use and describes new developments in the field. Intravascular UltrasoundIn the last 25 years IVUS has been established as the most commonly used intracoronary imaging device. An IVUS system consists of a flexible monorail catheter with an ultrasound transducer at its tip that emits ultrasound waves in the 10-40 MHz range and an electronics console to reconstruct the image (see Figure 1).1 After reflection from tissue, part of the ultrasound energy returns to the transducer and is converted into the image.There are two types of IVUS transducers for clinical use: the mechanical rotating transducer and the electronically switched phased array system.The mechanical transducer uses a single crystal on a rotational device, which visualises the entire vessel in cross-section providing better image quality (compared with phased array technology) of 100-150 μm.2 The main disadvantage of mechanical transducers is the central drive shaft that decreases flexibility and prevents the concurrent use of a central guidewire.3 However, newer rotational IVUS catheters have developed a monorail system that allows for the presence of a central guidewire.Phased array catheters use multiple transducer elements, which are mounted along the circumference of the catheter tip. Each element sends and receives ultrasounds from a sector and multiple sectors are gathered to produce a cross-sectional image of the artery. However, they are disadvantaged by a technically complex set-up, requiring detailed programming; 3 but some of the newer catheters are easier to set up.Intracoronary imaging of coronary vessels by IVUS is performed using standard coronary interventional techniques and equipment (guiding catheter and 0.014 inch angioplasty guidewire) for catheter delivery along the guidewire beyond the target lesion/area of interest. Intravenous heparin and glyceryl trinitrate (nitroglycerin) are routinely administered before imaging. The IVUS catheter is then drawn back across the tar...

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“…Previous studies using invasive techniques [34][35][36][37] have identified high-risk features such as thin-cap, low residual lumen area, and spotty calcification as the hallmark of high-risk plaques. These high-risk plaques identified by either IVUS or OCT were also associated with adverse clinical outcomes.…”

Section: Discussionmentioning

confidence: 99%

Rationale and design of the Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry: A comprehensive exploration of plaque progression and its impact on clinical outcomes from a multicenter serial coronary computed tomographic angiography study

Lee

Chang

Rizvi

et al. 2016

American Heart Journal

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Association Between IVUS Findings and Adverse Outcomes in Patients With Coronary Artery Disease

Cited by 457 publications

References 11 publications

Intracranial-Derived Atherosclerosis Assessment: An In Vitro Comparison between Virtual Histology by Intravascular Ultrasonography, 7T MRI, and Histopathologic Findings

Intracranial-Derived Atherosclerosis Assessment: An In Vitro Comparison between Virtual Histology by Intravascular Ultrasonography, 7T MRI, and Histopathologic Findings

Intravascular Ultrasound Versus Optical Coherence Tomography for Coronary Artery Imaging – Apples and Oranges?

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