Several hands are now working worldwide to reduce exposure to air pollution, especially in developing nations. Future steps should be determined and classified as possible research solutions and gaps from the massive bulk of research output. Therefore, a scientometric approach has been applied using VOSviewer to show an accurate picture and trend in the mentioned area “Air pollution exposure and health,“ and its signify issues. According to the proposed study, complete 26,859 documents were retrieved from the database (ISI Web of Science) related to air pollution exposure and health effects during 2018–2022. The mapping analysis is been conducted on the country’s collaboration, co-authorship, institutional collaboration, and co-occurrence of keywords. The data collected shows the information about published articles (upward trend) over the years. Based on the citations and publication database, countries like China and the USA play a prominent role in air pollution exposure and health-related research. The study clearly defines the 3 domains of research and 4 major themes that have been currently focused. The case studies related to pollution and its impact on climate and health, studies involving chemical characteristics and management practices, also Hazardous health effects, theme like association of air pollutants, chemical composition and characterization of aerosols, health impacts due to exposure and modelling and analytical approach have been the most researched topics in the past 5 years. The developing and developed countries might potentially change the research network and work structure in order to obtain advancement in the field of Air pollution and enhance measures on exposure and health. The following research attempts to provide insights to the researchers and health sectors by straightening out developments up to date and raveling the research gaps that are needed to be addressed regarding Air pollution health and exposure.