Association between lung function, physical activity level and postural evaluation variables in adult patients with cystic fibrosis

Cherobin, Inaê Angélica; Dalcin, Paulo de Tarso Roth; Ziegler, Bruna

doi:10.1111/crj.12698

Cited by 9 publications

(6 citation statements)

References 27 publications

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“…As in other studies, we found a significant correlation between age, FEV1, and sleep quality [ 19 , 32 , 33 ]. Young patients on average have a better lung function and less comorbidities that associate with sleep disturbances.…”

Section: Discussionsupporting

confidence: 90%

Association between habitual physical activity (HPA) and sleep quality in patients with cystic fibrosis

et al. 2020

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Purpose Sleep disturbances and poor sleep quality are known to be present in patients with CF. Regular physical activity plays an important role in the treatment of CF patients due to its positive influence on progression of disease and quality of life. The aim of this work is to create a home-based sleep and activity profile and to investigate the influence of habitual physical activity (HPA) on sleep quality in children, adolescents, and adults with CF. Methods A total of 109 CF patients (64 male, mean age 22.7 ± 12.0 years; mean ppFEV1 63.0 ± 26.7) were equipped with an actigraph for a home-based collection of data on sleep and activity over 4 weeks. Results Age, FEV1, and BMI affect sleep and activity in CF patients. Especially younger age and higher FEV1 show a great influence on certain aspects of sleep (SE, TST, TIB, WASO, # of awakenings) and activity and its different intensities. General HPA does not affect sleep, but there is a strong correlation between times spent in vigorous to very vigorous intensities and better sleep quality. Conclusion Besides younger age and higher FEV1, daily activity in higher intensities influences sleeping behavior of CF patients in a positive way. Patients with poor sleep quality and sleep disturbances possibly benefit from an intensification of physical activity in the home environment. Trail registration number: 14-6117-BO (University Duisburg-Essen) and NCT 03518697 (clinical trials).

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Section: Discussionsupporting

confidence: 90%

Association between habitual physical activity (HPA) and sleep quality in patients with cystic fibrosis

et al. 2020

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“…In adults with CF, deterioration in lung function has been associated with increased dorsal kyphosis [11,36], with changes in vertical alignment of the chest [37] and also with increased prevalence of vertebral fractures [36]. These postural deviations alter the conformation of the rib cage structures, placing the respiratory muscles at a mechanical disadvantage and, therefore, may also contribute for the reduction of thorax mobility.…”

Section: Discussionmentioning

confidence: 99%

“…In addition to impaired pulmonary function, children with CF have been shown to have reduced peak cough flow (PCF) values [9], high prevalence of musculoskeletal diseases [10] and postural changes [10][11], which have been related to the severity of pulmonary involvement [11], but there are still controversies on the subject [12], which deserves to be better studied.…”

Section: Introductionmentioning

confidence: 99%

Association between lung function, thoracoabdominal mobility and posture in cystic fibrosis: pilot study

et al. 2020

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Introduction: Deterioration of lung function is the main cause of mortality in cystic fibrosis (CF), so it is essential to study different related factors. Objective: To assess the association of pulmonary function with thoracoabdominal mobility and postural alignment in individuals with CF. Method: A cross-sectional study was performed in individuals with CF (8-17 years). Pulmonary function was assessed by spirometry. Thoracoabdominal mobility and postural alignment were evaluated by photogrammetry using the Postural Assessment Software (PAS/Sapo). Pearson correlation coefficient analysis was performed, and p < 0.05 was considered significant. Results: The following spirometric variables showed a decrease compared to predicted values: FEV1, FEV1/FVC, PEF and FEF25-75%. Postural assessment showed alterations in head horizontal alignment (HHA; 2.71 ± 2.23o), acromion horizontal alignment (AHA; 1.33 ± 1.35o), anterior superior iliac spine (ASIS) horizontal alignment (ASISHA; 1.11 ± 0.89o), angle between acromia and ASIS (AAASIS; 0.89 ± 0.39o), scapula horizontal asymmetry - T3 (SHAT3; 16.95 ± 12.03%), and asymmetry of the projection of the center of gravity within the base of support in the frontal (11.45 ± 8.10%) and sagittal (48.98 ± 18.55%) planes. A strong positive correlation was found between pulmonary function and thoracoabdominal mobility in the variables anteroposterior mobility of the upper chest (APMUC) and FVC (r = 0.818, p = 0.024), APMUC and FEV1 (r = 0.874, p = 0.010), and APMUC and FEF25-75% (r = 0.797, p = 0.032). A strong negative correlation was detected between FEV1/FVC and AHA (r = -0.761, p = 0.047). Conclusion: Our study showed in CF a reduction in pulmonary function, strong positive correlation between APMUC and pulmonary function, high prevalence of kyphoscoliosis and strong negative correlation between AHA and pulmonary function.

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“…A consistent positive association was found between lung function ( i.e. forced expiratory volume in 1 s, FEV 1 ) and PA in all age groups, regardless of the PA measuring method (strength of conclusion: bias assessment level 2) [ 30 , 32 , 36 , 38 , 43 , 44 , 46 , 47 , 51 – 53 , 56 , 57 , 61 , 62 ]. A consistent positive association was found between (maximal) exercise capacity and PA in adult and mixed populations (strength of conclusion: bias assessment level 2) [ 31 – 34 , 36 , 53 , 54 , 63 – 66 ].…”

Section: Resultsmentioning

confidence: 70%

“…Therefore, results from this systematic review should be interpreted with caution. Subjective methods such as questionnaires are quick, easy to use and have a low cost, but are associated with difficulties including errors in subject recall (especially for children), information provided by proxies and overestimation of PA to achieve social desirability [ 54 , 61 , 89 , 90 ]. For this purpose, incorporating objective measures of PA should continue to be a priority in PA research.…”

Section: Discussionmentioning

confidence: 99%

Physical activity and its correlates in people with cystic fibrosis: a systematic review

Kinaupenne

Craemer²,

Schaballie³

et al. 2022

Eur Respir Rev

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Cystic fibrosis (CF) is a life-shortening genetic disease, affecting multiple life domains including physical activity (PA). Although higher PA levels are associated with multiple health benefits, little insight exists on the PA level of people with CF (PwCF) compared to healthy peers. Evidence on the influencing factors (i.e. correlates) of PA in this clinical population is scarce, but essential to fully understand their PA behaviour. Therefore, the present review aims to provide an overview of the PA level of PwCF compared to healthy peers, and the correlates of PA in PwCF. A systematic search of three databases resulted in 46 included studies. Analysis of 16 studies showed that the CF population is equally active compared to healthy peers, but there is a trend towards less high-intensity PA in youths with CF. Furthermore, PA is positively associated with quality of life, lung function, (maximal) exercise capacity, bone mineral density and quadriceps force. Also, PA was lower on weekdays compared to weekend days and lower when experiencing pulmonary exacerbations. More high-quality research is required in PwCF, particularly longitudinal studies that further explore the correlates of PA, with PA investigated as a primary outcome and measured objectively.

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Association between lung function, physical activity level and postural evaluation variables in adult patients with cystic fibrosis

Abstract: Lung function in patients with CF disease is associated with higher thoracic kyphosis, shorter time in moderate and vigorous PA, and shorter distance covered in 6MWT. The accelerometer has been shown to be the best instrument for assessing PA in this public.

Cited by 9 publications

References 27 publications

Association between habitual physical activity (HPA) and sleep quality in patients with cystic fibrosis

Association between habitual physical activity (HPA) and sleep quality in patients with cystic fibrosis

Association between lung function, thoracoabdominal mobility and posture in cystic fibrosis: pilot study

Physical activity and its correlates in people with cystic fibrosis: a systematic review

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