Association between maternal second-trimester stress and adverse pregnancy outcomes according to pre-pregnancy body mass index and gestational weight gain

Zhang, Lixia; Zhu, Shuqi; Wu, Yue; Chen, Danqing; Liang, Zhaoxia

doi:10.3389/fpsyt.2023.1129014

Cited by 3 publications

(1 citation statement)

References 29 publications

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“…The VD receptor significantly interacted with the AhR, as shown in other cell types [45]. This inclusion of wider regulatory factors would allow future research to better link to how maternal stress, including discrimination stress, modulates pregnancy and fetal outcomes [46].…”

Section: Discussionmentioning

confidence: 87%

The Association of Vitamin D during Pregnancy and mRNA Expression Levels of Inflammatory Factors with Preterm Birth and Prelabor Rupture of Membranes

Alifu,

Si,

Qiu

et al. 2023

Nutrients

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The aim of this study was to elucidate the association between vitamin D (VD) and the risk for preterm birth (PTB) and prelabor rupture of membranes (PROM). This study included two parts, with a cohort study and a case-control study. Plasma 25-hydroxyvitamin vitamin D [25(OH)D] levels in three trimesters in the cohort study and maternal 25(OH)D before delivery in the case-control study were measured. Quantitative real-time PCR was used to detect relative mRNA expression levels of the inflammatory factors associated with pyroptosis in peripheral blood mononuclear cell (PBMC), placenta and fetal membranes. Multinomial logistic regression and the Wilcoxon test were applied to analyze the associations. In the cohort study, 6381 pregnant women were included. We found that VD deficiency in T3 (PTB without PROM: OR = 1.90, 95% CI: 1.02–3.55, Term PROM (TPROM): OR = 0.76, 95% CI: 0.59–0.98) and less change of 25(OH)D between T1 and T3 (PTB without PROM: OR = 2.32, 95% CI: 1.07–5.06, TPROM: OR = 0.73, 95% CI: 0.56–0.96) were associated with the increased risk of PTB without PROM, while there was a decreased risk of TPROM. Neither VD, nor the increase of VD during pregnancy was associated with the premature rupture of membranes preterm delivery (PPROM). In the case-control study, there were no associations between VD during delivery and PTB or PROM (TPROM: OR = 1.33, 95% CI: 0.52–3.44); PTB without PROM: OR = 1.66, 95% CI: 0.33–8.19; PPROM: OR = 1.19, 95% CI: 0.42–3.40). The mRNA expression of NLRP1 (NOD-like receptor thermal protein domain associated protein 1) (p = 0.0165) in PBMC in the TPROM group was higher than that in the term group, and IL-18 (p = 0.0064) was lower than that in the term group. Plasma 25(OH)D in T3 and the increase of 25(OH)D between T1 and T3 were associated with a lower risk for PTB without PROM but a higher risk for TPROM. Further studies are warranted to clarify the association between VD and PTB and PROM and its mechanism.

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Section: Discussionmentioning

confidence: 87%

The Association of Vitamin D during Pregnancy and mRNA Expression Levels of Inflammatory Factors with Preterm Birth and Prelabor Rupture of Membranes

Alifu,

Si,

Qiu

et al. 2023

Nutrients

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Correlation between hyperemesis gravidarum risk factors and body weight of first-trimester pregnant women

Handayani,

Salsabila,

Hijriyati

et al. 2024

J Pal Nurs Stud

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Background: Nausea and vomiting early in pregnancy are experienced by around 70-80% of pregnant women. If nausea and vomiting occur too often, it will become a pathological condition called hyperemesis gravidarum. Many factors trigger hyperemesis gravidarum, necessitating more in-depth research regarding the risk factors for hyperemesis gravidarum and their impact on the weight of pregnant women in the first trimester. Purpose: This study aimed to analyze the correlation between hyperemesis gravidarum risk factors and the body weight of first-trimester pregnant women in East Jakarta. Methods: A quantitative study employing descriptive analysis and a cross-sectional case-control method was conducted, including 84 first-trimester respondents selected using targeted sampling techniques. Data collection was performed using questionnaires, and data analysis was conducted using Chi-square. Results: There is a significant relationship between the risk factor variables for severe morning sickness, namely age, occupation, history of vomiting, anemia, and the outcome, which is the measurement of pregnant women’s weight. Conclusions: There is a relationship between age, occupation, pregnancy, history of vomiting, anemia, and mild stress with the results of weight measurement of pregnant women in the first 3 months of pregnancy.

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Establishment and validation of a prognostic model for premature rupture of membranes and preterm delivery in pregnant women after cervical conization

Xiu

2024

Am J Transl Res

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Association between maternal second-trimester stress and adverse pregnancy outcomes according to pre-pregnancy body mass index and gestational weight gain

Cited by 3 publications

References 29 publications

The Association of Vitamin D during Pregnancy and mRNA Expression Levels of Inflammatory Factors with Preterm Birth and Prelabor Rupture of Membranes

The Association of Vitamin D during Pregnancy and mRNA Expression Levels of Inflammatory Factors with Preterm Birth and Prelabor Rupture of Membranes

Correlation between hyperemesis gravidarum risk factors and body weight of first-trimester pregnant women

Establishment and validation of a prognostic model for premature rupture of membranes and preterm delivery in pregnant women after cervical conization

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