Association between Metabolic Syndrome Diagnosis and the Physical Activity—Sedentary Profile of Adolescents with Obesity: A Complementary Analysis of the Beta-JUDO Study

Julian, Valérie; Ciba, Iris; Olsson, Roger; Dahlbom, Marie; Furthner, Dieter; Gomahr, Julian; Maruszczak, Katharina; Mörwald, Katharina; Pixner, Thomas; Schneider, Anna-Maria; Pereira, Bruno; Duclos, Martine; Weghuber, Daniel; Torgerson, David; Bergsten, Peter; Forslund, Anders

doi:10.3390/nu14010060

Cited by 10 publications

(9 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Current evidence supports a stepwise approach that might start with targeting SED behaviors (step 1, i.e., supporting a shift from long periods of SED time to daily routines incorporating bouts of PA, even low-intensity PA) prior to increasing MVPA (step 2), when increasing MVPA is not possible in youths with obesity. IR, low HDL-C, and a high cumulative cardiometabolic risk score, but also with liver fat content and surrogate markers of nonalcoholic fatty liver disease, independently of MVPA time [4,[27][28][29].…”

Section: Resultsmentioning

confidence: 99%

There Is a Clinical Need to Consider the Physical Activity: Sedentary Pattern in Children with Obesity – Position Paper of the European Childhood Obesity Group

Julian¹,

Ring-Dimitriou²,

Wyszyńska³

et al. 2022

Ann Nutr Metab

Self Cite

View full text Add to dashboard Cite

Introduction: While international prevention guidelines recently advocated, in addition to moderate and vigorous physical activity (MVPA) guidelines, for a minimization of sedentary time (SED), recommendations remain to be developed for youths with obesity. Methods: A literature search was conducted in PubMed, the Cochrane Library plus the reference lists of selected articles for relevant publications in English, including original papers, systematic reviews, and meta-analyses, with search terms “sedentary behaviors” or “sedentary time” or “screen time” AND “children” or “adolescents” AND “obesity” or “adiposity” or “cardiometabolic risk” or “cardiometabolic disease”. The results were summarized as a narrative review and presented to the scientific board of the European Childhood Obesity Group (ECOG) who then discussed their implication in clinical practice and proposed the position outlined in this paper. Results: SED and screen times are associated with adiposity and cardiometabolic risks independently of youths’ physical activity level. Besides considering MVPA and SED times as separate variables, comprehensive studies have questioned the impact of different patterns of MVPA and SED levels. Although lower body adiposity and better cardiometabolic health are achieved among those with desirable movement behaviors patterns (i.e., more MVPA/less SED or active/not sedentary), youths with intermediate patterns (i.e., high MVPA/high SED and low MVPA/low SED, or active /sedentary and inactive/not sedentary) have been found to be associated with intermediate risks. Conclusion: There is a need to decrease SED behaviors irrespective of MVPA and to consider PA-SED patterns in youths with obesity. The European Childhood Obesity Group (ECOG) encourages anti-obesity strategies targeting both physical activity (PA) and SED behaviors to support the shift from long periods of SED time, especially screen time, to daily routines incorporating bouts of PA. Stepwise or sequential approaches to movement behavior counseling might start with targeting SED at first to decrease cardiometabolic risks when implementing MVPA is not yet possible.

show abstract

Section: Resultsmentioning

confidence: 99%

There Is a Clinical Need to Consider the Physical Activity: Sedentary Pattern in Children with Obesity – Position Paper of the European Childhood Obesity Group

Julian¹,

Ring-Dimitriou²,

Wyszyńska³

et al. 2022

Ann Nutr Metab

Self Cite

View full text Add to dashboard Cite

show abstract

“…It has been associated with insulin resistance and cardiometabolic health in adolescents [48]. Secondly, as previously discussed [22,23], while accelerometry is the gold standard method for measuring movements-related behaviors, MVPA has been potentially overestimated at the expense of LPA. While Actical was shown comparable to the Actigraph GT3X in youths [49], Migueles et al recently demonstrated that MVPA time largely differed across attachment sites (hip vs wrist), acceleration metrics (number of days and hours per day) and cut-points in youths with obesity [50].…”

Section: Discussionmentioning

confidence: 99%

“…Movements related behaviors were assessed with the accelerometer Actical ® (Philips Respironics, Inc, Murrysville, PA). As previously described [23], it is an omni-directional waterproof device recording accelerations in the range of 0.05-2.0 g, sensitive to movements in the range of 0.35-3.5 Hz, and able to record the magnitude of acceleration and deceleration associated with every movement. The signal was scored as a "count" which was summed over a 1 minute epoch.…”

Section: Physical Activity and Sedentary Timementioning

confidence: 99%

“…As it remains di cult to implement MVPA in youths with obesity in clinical practice, our team conducted a cross sectional study comparing 7day/24h accelerometry-based patterns of SED (more sedentary, SED + vs less sedentary, SED -), MVPA (more active, MVPA + vs less active, MVPA-) and combinations of SED and MVPA times (SED-/MVPA+, SED-/MVPA-, SED+/MVPA+, SED+/MVPA-). Results showed that i) low SED/high MVPA pattern had the most desirable cardiometabolic pro le, ii) SED-/MVPA-pattern had lower fat mass, insulin resistance, dyslipidemia and metabolic syndrome risk score, independent of BMI, in comparison with SED+/MVPA + pattern, and iii) SED time was correlated with cardiometabolic risks independently of MVPA [22,23]. Considering the strong relationships between cardiometabolic comorbidities and NAFLD [4,24], it seemed relevant to question whether movement behaviors patterns might be associated with NAFLD markers in the same population.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Association between fatty liver disease markers and physical activity and sedentary time in children and adolescents with obesity

Julian

Bergsten

Ennequin

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

Purpose: To compare patterns of sedentary (SED) time (more sedentary, SED+ vs less sedentary, SED-), moderate to vigorous physical activity (MVPA) time (more active, MVPA+ vs less active, MVPA-) and combinations of behaviors (SED-/MVPA+, SED-/MVPA-, SED+/MVPA+, SED+/MVPA-) regarding nonalcoholic fatty liver diseases (NAFLD) markers. Methods: This cross-sectional study included 134 subjects (13.4±2.2yrs, body mass index (BMI) 98.9±0.7 percentile, 48.5% females) who underwent 24h/7day accelerometry, anthropometric and biochemical markers (alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), AST/ALT and Fatty Liver Index (FLI)). A subgroup of 39 patients underwent magnetic resonance imaging-liver fat content (MRI-LFC).Results: Hepatic health was better in SED- [lower ALT, GGT and MRI-LFC (p<0.05), higher AST/ALT (p<0.01)] vs SED+ and in MVPA+ [lower ALT (p<0.05) and FLI (p=0.001), higher AST/ALT (p<0.01)] vs MVPA- groups after adjustment for age, gender and Tanner stages. SED-/MVPA+ group had the best hepatic health. SED-/MVPA- group had lower ALT and GGT and higher AST/ALT (p<0.05) in comparison with SED+/MVPA+ group independently of BMI. SED time was positively associated with biochemical (high ALT, low AST/ALT ratio) and imaging (high MRI-LFC) markers independently of MVPA. MVPA time was associated with biochemical markers (low ALT, FLI, high AST/ALT) but these associations were no longer significant after adjustment for SED time, except for FLI (p<0.001). Conclusions: Lower SED time is associated with better hepatic health independently of MVPA. Reducing SED time might be a first step in the management of pediatric obesity NAFLD when increasing MVPA is not possible.

show abstract

“…The prevalence of adiposity is one of the biggest concerns for global public health. Obesity has been significantly associated with the increased risk of type 2 diabetes, hypertension, cardiovascular diseases, certain cancers ( Dwivedi et al, 2020 ; Julian et al, 2022 ; Wagner and Brath, 2012 ), and increased mortality ( Whitlock et al, 2009 ). Adiposity indicates a state of positive energy balance.…”

Section: Introductionmentioning

confidence: 99%

Objectively determined physical activity and adiposity measures in adult women: A systematic review and meta-analysis

Wiltshire

Baker

et al. 2022

Front. Physiol.

View full text Add to dashboard Cite

The prevalence of adiposity is increasing among adult women. Although emerging evidence suggest that all patterns of heightened physical activity (PA) are important to benefit adiposity, the relationship between objectively assessed intensities of PA and adiposity in women has not yet been assessed. Therefore, this systematic review and meta-analysis aims to qualitatively synthesize and quantitatively assess the evidence for any relationship between objectively measured PA and a wide range of adiposity indicators to guide PA prescription in adult women. Four databases (PubMed, Web of Science, Scopus, and the Cochrane library) were searched for eligible studies. 35 studies were included (25 observational and 10 interventional studies), with a total of 9,176 women from 20 countries included. The overall pooled correlation for random effects model (n = 1 intervention and n = 15 cross-sectional studies) revealed that the total volume of physical activity (TPA) was moderately associated with percentage body fat (%BF) (r = −0.59; 95% CI: −1.11, −0.24; p = 0.003). There was a weak but significant association between MVPA with body mass index (BMI), waist circumference (WC), and visceral adiposity. Daily steps were significantly associated with BMI, %BF, WC, and fat mass, with the strongest association with %BF (r = −0.41; 95% CI: −0.66, −0.19; p < 0.001). Walking programs resulting in increasing daily steps only had a significant effect on WC (SMD = −0.35; 95% CI: −0.65, −0.05; p = 0.02). Overall, objectively determined PA in terms of steps, TPA and MVPA were favorably associated with adiposity outcomes. The improvement in adiposity can be achieved by simply accumulating more PA than previously and adiposity is more likely to be benefited by PA performed at higher intensity. Nonetheless, these results should be interpreted with caution as there were a small number of studies included in the meta-analysis and the majority of studies included utilized cross-sectional designs.

show abstract

Association between Metabolic Syndrome Diagnosis and the Physical Activity—Sedentary Profile of Adolescents with Obesity: A Complementary Analysis of the Beta-JUDO Study

Cited by 10 publications

References 56 publications

There Is a Clinical Need to Consider the Physical Activity: Sedentary Pattern in Children with Obesity – Position Paper of the European Childhood Obesity Group

There Is a Clinical Need to Consider the Physical Activity: Sedentary Pattern in Children with Obesity – Position Paper of the European Childhood Obesity Group

Association between fatty liver disease markers and physical activity and sedentary time in children and adolescents with obesity

Objectively determined physical activity and adiposity measures in adult women: A systematic review and meta-analysis

Contact Info

Product

Resources

About