Association between motoric cognitive risk syndrome and frailty among older Chinese adults

Abstract

Background: Motoric cognitive risk syndrome (MCR) is a newly proposed predementia syndrome incorporating subjective cognitive complaints and slow gait. Previous studies have reported that subjective cognitive complaints and slow gait are associated with frailty in cognitively unimpaired older adults, but little is known about the link between MCR and frailty in older adults. Therefore, the aim of the study was to explore the associations of MCR and its components with frailty in older Chinese adults. Methods: In an observational cross-sectional study, a total of 429 older adults aged 60 years and older were admitted to the geriatric department. According to MCR criteria, all participants were classified into 4 groups: 1) the MCR group; 2) the subjective cognitive complaints only group; 3) the slow gait only group; and 4) the healthy control group. Physical frailty was assessed by the Clinical Frailty Scale (CFS). Multivariate logistic regression analysis was used to examine the association between MCR and frailty in older adults.Results: The prevalence rates of subjective cognitive complaints, slow gait and MCR were 15.9, 10.0 and 4.0%, respectively. After adjusting for confounding variables, the logistic regression analysis showed that slow gait (odds ratio [OR]: 3.40, 95% confidence interval [CI]: 1.40-8.23, P = 0.007) and MCR (OR: 5.53, 95% CI: 1.46-20.89, P = 0.012) were independently associated with frailty, but subjective cognitive complaints were not. Conclusions: MCR and slow gait were significantly associated with frailty in older Chinese adults. Further studies should prospectively determine the causal relationship between MCR and frailty.

Association between depression and motoric cognitive risk syndrome among community‐dwelling older adults in China: A 4‐year prospective cohort study

“…The prevalence of MCR in community-dwelling older adults ranged from 2% to 27% [30], which may be attributed to how MCR criteria are operationalized and how different populations were recruited in previous studies. In this study, the MCR prevalence was 10.4% at baseline, higher than in a previous study in 429 older adults aged 60 years and older admitted to a geriatric department in China [31] (4.0%). Our findings were similar to those of studies among community-dwelling Chinese elderly people (12.8% in men and 12.6% in women) [3] and in Mexican elderly people [32] (14.3%), which indicated that MCR might be more severe among the elderly living in the community.…”

Combined effect of sarcopenia and osteoporosis on the prevalence of mild cognitive impairment in Chinese community-dwelling old adults

“…36 In contrast, a previous study suggested that subjective cognition was not associated with frailty syndrome. 37 The reason for this observation may be that the accuracy of self-reported cognitive complaints may be affected by many factors. Moreover, an interesting study con rmed that osteosarcopenia is often associated with the risks of falls or osteoporotic fractures.…”

Motoric Cognitive Risk Syndrome and Cognitive Frailty

“…With MCR syndrome being a relatively new concept, prevalence rates have been complicated since no specific cognitive test has been identified for diagnosis and reported rates vary from 2% to 27% of populations worldwide 11. This may also be related to cultural differences across the globe in how and if people identify and report cognitive changes 11…”