Association between organophosphate pesticides exposure and thyroid hormones in floriculture workers

Association between organochlorine pesticide exposure and thyroid hormones in floriculture workers

“…To our knowledge, this is the first study that evaluates the association between serum p,p'-DDE concentration and thyroid profile hormone levels in agricultural workers, taking into consideration exposure to organophosphate pesticides, also considered thyroid disrupters (Meeker et al, 2006;Lacasaña et al, 2010;Fortenberry et al, 2012).…”

“…Details of population and design of the study have been reported elsewhere (Lacasaña et al, 2010). Workers were identified using the employee records of 57 businesses belonging to two associations of floriculture growers.…”

“…The characteristics of the study population are described in a previous paper (Lacasaña et al, 2010). Briefly, over 70% of the workers applied or mixed pesticides, and over 60% were between 20 and 39 years old.…”

“…The aim of this analysis was to assess the association between serum levels of p,p'-DDE and serum levels of thyroid hormones, in Mexican male floriculture workers who have been exposed to DDT, adjusting by potential confounding variables including urinary dialkylphosphates (DAPs), since organophosphate pesticides have been considered as thyroid endocrine disruptors (Meeker et al, 2006;Fortenberry et al, 2012) and were largely used by these workers (Lacasaña et al, 2010).…”

Effects of commercial formulations of deltamethrin and/or thiacloprid on thyroid hormone levels in rat serum

“…Environmental chemicals may interfere on the thyroid gland function through different mechanisms of action, for example, at the receptor level, in binding to transport proteins, in cellular uptake mechanisms or in modifying the metabolism of thyroid hormones (Boas et al, 2006;Lacasana et al, 2010). Endocrine disrupters can throw off the system by sending the wrong signals or blocking the right signals.…”