2022
DOI: 10.1055/a-1988-5047
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Association between Platelet Count and Treatment Effect of Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes

Abstract: Background: The relative efficacy and safety of ticagrelor and prasugrel based dual antiplatelet therapy (DAPT) strategies according to the platelet count (PC) in patients with acute coronary syndromes (ACS) has not been defined. Methods: This is a post-hoc analysis of the ISAR-REACT 5 trial, in which patients presenting with ACS were randomized to treatment with ticagrelor versus prasugrel. Patients were divided into quartiles according to PC. The primary endpoint was incidence of death, myocardial infarctio… Show more

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“…There was also no history of sudden chest tightness, chest pain or elevated cardiac enzymes. None of these aforementioned observations conformed to the manifestations of acute myocardial infarction ( 9 ). Subsequent echocardiography revealed enlargement of the whole heart and thickening of the posterior wall of the left ventricle.…”
Section: Discussionmentioning
confidence: 81%
“…There was also no history of sudden chest tightness, chest pain or elevated cardiac enzymes. None of these aforementioned observations conformed to the manifestations of acute myocardial infarction ( 9 ). Subsequent echocardiography revealed enlargement of the whole heart and thickening of the posterior wall of the left ventricle.…”
Section: Discussionmentioning
confidence: 81%