2020
DOI: 10.21203/rs.3.rs-84448/v1
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Association Between Pyrethrum Knockdown Time and Sodium Channel Genotypes in California Aedes Aegypti

Abstract: Background: Since their detection in 2013, Aedes aegypti has become a widespread urban pest in California. The availability of cryptic larval breeding sites in residential areas and resistance to insecticides pose significant challenges to control efforts. Resistance to pyrethroids is largely attributed to mutations in the voltage gated sodium channels (VGSC), the pyrethroid site of action. However, past studies have indicated that VGSC mutations may not be entirely predictive of the observed resistance phenot… Show more

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