The mission of JAMA Network Open is to improve health, health care, and health equity worldwide. 1 War is the antithesis of health. It affects combatants and civilians, families, communities, institutions, and the environment. All of these become less healthy, each are wounded, and each can die. By definition, war is inequitable.While the attention of the world is currently on the brutal war in Ukraine, 2 there have been constant and escalating conflicts around the world since the end of World War II. An estimated 80 100 people died in 2020 alone from organized violence-and state-based conflicts. 3 There are ongoing conflicts in Syria, Yemen, and Ethiopia and many other parts of the world; the Uppsala Conflict Data Program 4 lists 21 555 fatalities from organized violence in March 2022, with 2717 in Africa, 482 in Asia, 322 in the Middle East, 569 in the Americas, and 17 465 in Europe. Contemporary wars and civil conflicts have disproportionately affected civilians, some directly, but far more indirectly through the breakdown in public health, spread of infectious diseases, starvation owing to related famines and population malnutrition, disruption of infrastructures (including health systems), forced migration and internal displacement, and assaults and trafficking of women and children.As we have done for other important issues, JAMA Network Open is issuing a call for papers on the health effects of war and interventions that address the health consequences of war. This topic is not new for the journal. We have published studies on both direct and indirect effects of war, those occurring in the short term as well as those occurring over longer time horizons. Studies have included the long-term outcomes associated with sulfur mustard in survivors of the Iran-Iraq war 5 and studies on traumatic brain injury, 6 which many call the signature injury of the wars in Iraq and Afghanistan after September 11, 2001. The effects of combat on veterans' mental health have long been known; however, a study of suicide in the US Army over the last 100 years showed that the rate during the Afghanistan and Iraq wars was 4-to 6-fold greater than it was during the last year of World War II, 7 and the mental health consequences were associated with the types of combat experienced. [8][9][10] Additionally, reports of randomized clinical trials have compared therapies for veterans with military-related posttraumatic stress disorder. 11,12 Gender-based violence during war, whether from sexual assault, enslavement, or partner violence, has long-term effects on the mental health of its survivors, which can persist for years. 13,14 The high prevalence of self-reported severe posttraumatic stress symptoms in Rohingya refugees suggests that the trauma of displacement and consequences of violent military persecution will also persist. 15 Children are exposed to the violence of war in their families, neighborhoods, and communities. A study from Western Chitwan in Nepal found that children younger than 11 years who witnessed beatings related t...