Association Between Rheumatoid Arthritis and Health-Related Quality of Life in Korean Women Aged 50 Years and Over

Park, Hyejin

doi:10.22159/ajpcr.2017.v10i5.17749

Cited by 6 publications

(9 citation statements)

References 14 publications

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“…According to our findings, the responses from the utility score and the WTP values were consistent with prior expectations [18,21]. For each scenario, the utility associated with the more severe health states was lower than that of the less severe health states.…”

Section: Reliabilitysupporting

confidence: 84%

Reliability and Validity of Hypothetical Scenarios for Estimating Willingness to Pay (Wtp) Per Quality Adjusted Life Year (Qaly) in Indonesia Setting

Kristina

Endarti

Andayani

et al. 2017

Int J Pharm Pharm Sci

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Objective: To estimate validity and reliability of WTP questionnaire which WTP value can be taken as an indication of the monetary value of health gains, which may carry information regarding the appropriate height of the cost-effectiveness threshold.Methods: Three hundred respondents, in Yogyakarta province, Indonesia, were interviewed during June 2017. We examine a value of WTP associated with the following scenarios: 1) improving moderate condition; 2) extending life during terminal illness, and 3) lifesaving. The interview ascertained maximum hypothetical WTP for one QALY using a dichotomous bidding format with an open-ended final question, along with questions about the socio-economic factors. Concerning validity, the WTP of the 3 versions of hypothetical scenarios were compared as known-group validity and analysis of the sensitivity and specificity was performed. Test-retest reliability and alpha Cronbach were employed to measure internal consistency.Results: Analysis generally confirmed the validity and reliability of the WTP hypothetical scenarios. In terms of known group validity, there was significant difference across two scenarios (treatment v. s lifesaving), but no significant difference between mean WTP for treatment and terminal illness was found. Mean WTP for terminal illness (38 Million IDR) and lifesaving scenario (16 Million IDR) was significantly higher than that of treatment scenario (14 Million IDR). The WTP instrument showed good convergent validity (r=0.784), when comparing correlation between WTP value and utility score. Estimation of scenario's sensitivity and specificity in deriving expected WTP were 70.33 % and 38.98 %, respectively. The positive and negative predictive values were 64 % and 46 %. The test-retest reliability of WTP values indices excellent stability and reliability of the instrument with Spearman's rank correlation coefficient of 0.816 (p<0.001) Conclusion:This study demonstrated that the WTP instrument is feasible and relatively reliable for measuring the WTP values in Indonesia. For wider application of the instrument, its validity should be investigated further. Meanwhile, adoption of WTP as an empirical evidence of societal values is encouraged.

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Section: Reliabilitysupporting

confidence: 84%

Reliability and Validity of Hypothetical Scenarios for Estimating Willingness to Pay (Wtp) Per Quality Adjusted Life Year (Qaly) in Indonesia Setting

Kristina

Endarti

Andayani

et al. 2017

Int J Pharm Pharm Sci

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“…Thirty‐one studies reported utility scores of RA patients 22‐24,34‐42,45,47‐63,65 . The pooled mean EQ‐5D score was 0.66 (95% CI 0.63‐0.69) with high heterogeneity I 2 = 99.65% (Figure 2A).…”

Section: Resultsmentioning

confidence: 99%

“…Thirty-one studies reported utility scores of RA patie nts. [22][23][24][34][35][36][37][38][39][40][41][42]45,[47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62][63]65 The pooled mean EQ-5D score was 0.66 (95% CI 0.63-0.69) with high heterogeneity I 2 = 99.65% (Figure 2A).…”

Section: Overall Pooling Of Eq-5dmentioning

confidence: 99%

Health‐related quality of life in rheumatoid arthritis: Systematic review and meta‐analysis of EuroQoL (EQ‐5D) utility scores from Asia

2021

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Introduction Region‐specific health‐related quality of life (HRQoL) scores or utility values are representative and pivotal for economic evaluations as they are influenced by the value judgment of the local population. This study systematically reviewed and pooled EuroQoL‐5 Dimension (EQ‐5D) utility scores of rheumatoid arthritis (RA) across primary studies from Asia. Methods Studies reporting EQ‐5D utility scores among adult RA patients from Asian countries were systematically searched in PubMed‐Medline, Scopus and Embase since inception through February 2020. Selected studies were systematically reviewed and study quality assessment was performed. Meta‐analysis was performed using a random‐effect model with subgroup and meta‐regression analysis to explore heterogeneity. Results Among 1391 searched articles, 37 studies with 31 983 participants were systematically reviewed and meta‐analysis was conducted among 31 studies. The pooled EQ‐5D scores and EQ‐5D visual analog score were 0.66 (95% CI 0.63‐0.69, I2 = 99.65%) and 61.21 (50.73‐71.69, I2 = 99.56%) respectively with high heterogeneity. For RA patients with no, low, moderate and high disease activity based on Disease Activity Score (DAS)‐28, the pooled EQ‐5D scores were 0.78 (0.65‐0.90), 0.73 (0.65‐0.80), 0.53 (0.32‐ 0.74), and 0.47 (0.32‐0.62), respectively. On meta‐regression, age of patients (P < .05) was positively associated and use of glucocorticoids (P < .05) was inversely associated with utility values. Conclusion Lower EQ‐5D scores were associated with severe disease activity, increasing age and female gender among RA patients. The study provides pooled EQ‐5D scores for RA patients that are useful inputs for cost‐utility studies in Asia.

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“…Examination included general physical examination along with cardiovascular systemic examination and local knee examination. Orthopaedic evaluation was done using K-L grading 10 and CV risk was determined using the JBS3 CV risk score calculator. 15 Fasting blood sample was collected to know the levels of their serum total cholesterol and serum high density lipoprotein.…”

Section: Methodsmentioning

confidence: 99%

“…Patients diagnosed with knee osteoarthritis (Kellgren and Lawrence (KL) grade ≥2 on knee X-ray 9 ) and ≥50 years old 10 were invited to take part. The KL grading system is as follows:…”

Section: Study Participantsmentioning

confidence: 99%

Cross-sectional assessment of cardiovascular risk factors in patients with knee osteoarthritis

et al. 2022

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Background: Osteoarthritis (OA) and cardiovascular disease (CVD) are prevalent in India. However, there is dearth of literature among Indians studying the relationship between the two. This study was carried out to assess various cardiovascular (CV) risk factors in patients with knee OA with an objective to investigate their association, screening and management. Methods: In total, 225 patients were included in this cross-sectional study. Participants were diagnosed with knee OA on the basis of the Kellgren and Lawrence (K-L) classification of their radiograph. Participants were also assessed for CV risk factors; age, body mass index, systolic blood pressure, diabetes mellitus, total cholesterol, high-density lipoprotein, smoking. Joint British Society QRisk3 calculator (JBS3) a comprehensive risk score calculator as well as a screening tool, which produces three more variables, namely 10-years risk of developing CVD, physiological heart age and life expectancy, was used. Chi Square, Fishers exact test and one-way ANOVA tests were used to compare the categorical and quantitative variables, respectively.. Multiple regression analysis was done to adjust the multiple con-founders and determine their significance. Results: Patients with severe knee OA had a statistically significantly higher prevalence of CV risk factors (p<0.05). Grade 4 knee OA patients were found to have a mean JBS3 risk of 38%, heart age of 82 years and life expectancy of 77 years as compared to grade 2 patients who had a mean JBS3 risk of 11%, heart age of 63 years and life expectancy of 82 years. Conclusions: Our study concluded that there is a strong relation between knee OA and CVD, with CV risk score being positively correlated to the severity of OA.

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Association Between Rheumatoid Arthritis and Health-Related Quality of Life in Korean Women Aged 50 Years and Over

Cited by 6 publications

References 14 publications

Reliability and Validity of Hypothetical Scenarios for Estimating Willingness to Pay (Wtp) Per Quality Adjusted Life Year (Qaly) in Indonesia Setting

Reliability and Validity of Hypothetical Scenarios for Estimating Willingness to Pay (Wtp) Per Quality Adjusted Life Year (Qaly) in Indonesia Setting

Health‐related quality of life in rheumatoid arthritis: Systematic review and meta‐analysis of EuroQoL (EQ‐5D) utility scores from Asia

Cross-sectional assessment of cardiovascular risk factors in patients with knee osteoarthritis

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