Association between severe lumbar disc degeneration and self-reported occupational physical loading

Salo, Sami; Hurri, H; Rikkonen, Toni; Sund, Reijo; Kröger, Heikki; Sirola, Joonas

doi:10.1002/1348-9585.12316

Cited by 8 publications

(9 citation statements)

References 49 publications

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“…Despite the protective effects of estrogen on musculoskeletal structures such as IVD [21], the high morbidity of IVDD in women may be due to pregnancy, menopause, and relatively weak spinal muscular strength. Although it was reported that IVDD was relevant to high BMI [20], the results of the present study showed that BMI was not statistically significant in univariate logistics regression analysis and not the strongest predictors in the LASSO regression analysis. Gout as a metabolic disease was also one of the potential risk factors in the development of IVDD.…”

Section: Discussioncontrasting

confidence: 98%

“…However, environmental factors, such as lifestyles and dietary habits that are closely relevant to metabolic diseases and systemic diseases, can be consciously controlled and modified to improve human's health. Adverse lifestyle-related factors including high BMI, lack of physical activity and smoking can lead to or aggregate IVDD [ 20 ]. In addition, previous studies reported that metabolic diseases such as diabetes and obesity were associated with the development of IVDD [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

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Development and Validation of a Novel Nomogram to Predict the Risk of Intervertebral Disc Degeneration

Sun

Wang

et al. 2022

Mediators of Inflammation

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Intervertebral disc degeneration (IVDD) has been a complex disorder resulted from genetic and environmental risk factors. The aim of this study was to identify the risk factors associated with IVDD in orthopaedic patients and develop a prediction model for predicting the risk of IVDD. A total of 309 patients were retrospectively included in the study and randomly divided into the training group and the validation group. The least absolute shrinkage and selection operator regression (LASSO) and the univariate logistic regression analysis were used to optimize factors selection for the IVDD risk model. Multivariable logistic regression analysis was used to establish a predicting nomogram model incorporating the factors. In addition, discrimination, calibration, and clinical usefulness of the nomogram model were evaluated via the C-index, receiver operating characteristic (ROC) curve, calibration plot, and decision curve analysis (DCA). Then, based on the results above, the relationship between IVDD and angiotensin II (AngII) level in peripheral blood was examined prospectively. The predictors of the nomogram include age, sex, hypertension, diabetes, gout, working posture, and exercising hours per week. The C -index values of the training and validation groups were 0.916 (95% CI, 0.876-0.956) and 0.949 (95% CI, 0.909-0.989), respectively, which indicated that the model displayed good discrimination. In addition, the area under the curve (AUC) values of the ROC curve of the training and the validation group were 0.815 (95% CI, 0.759-0.870) and 0.805 (95% CI, 0.718-0.892), respectively, revealing the satisfactory discrimination performance of the model. The prospective investigation showed that the average AngII level in the degenerated group ( 97.62 ± 44.02 pg/mL) was significantly higher than that in the nondegenerated group ( 52.91 ± 9.01 pg/mL) ( p < 0.001 ). This present study explored the risk factors for IVDD and established a prediction model, which would effectively predict the risk of IVDD. In addition, based on the prediction model, AngII was revealed to be a potentially auxiliary clinical diagnostic marker for IVDD.

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Section: Discussioncontrasting

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Development and Validation of a Novel Nomogram to Predict the Risk of Intervertebral Disc Degeneration

Sun

Wang

et al. 2022

Mediators of Inflammation

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“…Occupation is also an important risk factor, and the results of this study suggest that people who engage in heavy physical activity or occupations that require prolonged sedentary standing may have poorer postoperative clinical outcomes than other patients. Salo et al ( 27 ). conducted a prospective cohort study, which included 1022 patients and assessed the degree of intervertebral disc degeneration by measuring the Pfirrmann grade of lumbar intervertebral discs on MRI, and then the relationship between occupational physical load and intervertebral disc degeneration was assessed.…”

Section: Discussionmentioning

confidence: 99%

Development, validation, and visualization of a web-based nomogram to predict the effect of tubular microdiscectomy for lumbar disc herniation

Chen

Lin

et al. 2023

Front. Surg.

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ObjectiveThe purpose of this study was to retrospectively collect the relevant clinical data of lumbar disc herniation (LDH) patients treated with the tubular microdiscectomy (TMD) technique, and to develop and validate a prediction model for predicting the treatment improvement rate of TMD in LDH patients at 1 year after surgery.MethodsRelevant clinical data of LDH patients treated with the TMD technology were retrospectively collected. The follow-up period was 1 year after surgery. A total of 43 possible predictors were included, and the treatment improvement rate of the Japanese Orthopedic Association (JOA) score of the lumbar spine at 1 year after TMD was used as an outcome measure. The least absolute shrinkage and selection operator (LASSO) method was used to screen out the most important predictors affecting the outcome indicators. In addition, logistic regression was used to construct the model, and a nomogram of the prediction model was drawn.ResultsA total of 273 patients with LDH were included in this study. Age, occupational factors, osteoporosis, Pfirrmann classification of intervertebral disc degeneration, and preoperative Oswestry Disability Index (ODI) were screened out from the 43 possible predictors based on LASSO regression. A total of 5 predictors were included while drawing a nomogram of the model. The area under the ROC curve (AUC) value of the model was 0.795.ConclusionsIn this study, we successfully developed a good clinical prediction model that can predict the effect of TMD for LDH. A web calculator was designed on the basis of the model (https://fabinlin.shinyapps.io/DynNomapp/).

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“…A herniated intervertebral disc of the lumbar spine (i.e., displacement of cartilage, fluid or bone of an intervertebral disc outside the borders of the disc space or its joints) is one of the most serious causes of low-back pain [ 55 ]. This condition is frequent in work occupational categories, including heavy load workers [ 56 ], sedentary workers [ 57 ] and health professionals [ 58 ].…”

Section: Discussionmentioning

confidence: 99%

Āsana for Back, Hips and Legs to Prevent Musculoskeletal Disorders among Dental Professionals: In-Office Yóga Protocol

Gandolfi,

Zamparini,

Spinelli

et al. 2023

JFMK

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Dental professionals are exposed to significant unavoidable physical stress, and theoretical ergonomic recommendations for a sitting workplace are inapplicable in many dental activities. Work-related musculoskeletal disorders (WMSDs) represent a serious health problem among dental professionals (prevalence: 64–93%), showing involvement of 34–60% for the low back and 15–25% for the hips. Muscle stress; prolonged sitting; forward bending and twisting of the torso and head; unbalanced working postures with asymmetrical weight on the hips and uneven shoulders; and others are inevitable for dental professionals. Therefore, the approach for the prevention and treatment of WMSDs must be therapeutic and compensatory. This project was conceived to provide a Yoga protocol for dental professionals to prevent or treat WMSDs from a preventive medicine perspective, and it would represent a Yoga-based guideline for the self-cure and prevention of musculoskeletal problems. Methods: Specific Yoga positions (āsana, such as Virāsana, Virabhadrāsana, Garudāsana, Utkatāsana, Trikonāsana, Anuvittāsana, Chakrāsana, Uttanāsana, Pashimottanāsana) have been selected, elaborated on and adapted to be practiced in a dental office using a dental stool or the dental office walls or a dental unit chair. The protocol is specifically devised for dental professionals (dentists, dental hygienists and dental assistants) and targeted for the low back, hips and legs (including knees and ankles). The protocol includes Visranta Karaka Sthiti (supported positions) in sitting (Upavistha Sthiti) and standing (Utthistha Sthiti) positions, twisting/torsions (Parivrtta), flexions/forward bend positions (Pashima) and extensions/arching (Purva) for musculo-articular system decompression and mobilization. Results: Over 60 Yogāsana—specifically ideated for back detensioning and mobilization, lumbar lordosis restoration, trunk side elongation, hip release and leg stretches and decontraction—are shown and described. The paper provides a meticulous description for each position, including the detailed movement, recommendations and mistakes to avoid, and the breathing pattern (breath control) in all the breath-driven movements (āsana in vinyāsa). An exhaustive analysis of posture-related disorders affecting the lower body among dental professionals is reported, including low-back pain, hip pain and disorders, piriformis syndrome and quadratus femoris dysfunction (gluteal pain), iliopsoas syndrome, multifidus disorders, femoroacetabular and ischiofemoral impingement, spinopelvic mobility, lumbopelvic rhythm, impairment syndromes, lower crossed syndrome, leg pain, knee pain and ankle disorders. Conclusions: A detailed guideline of āsana for low-back decompression, hip joint destress, piriformis and gluteal muscle release, lumbar lordosis recovery and a spinopelvic mobility increase has been elaborated on. The designed Yogāsana protocol represents a powerful tool for dental professionals to provide relief to retracted stiff muscles and unbalanced musculoskeletal structures in the lower body.

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Association between severe lumbar disc degeneration and self-reported occupational physical loading

Cited by 8 publications

References 49 publications

Development and Validation of a Novel Nomogram to Predict the Risk of Intervertebral Disc Degeneration

Development and Validation of a Novel Nomogram to Predict the Risk of Intervertebral Disc Degeneration

Development, validation, and visualization of a web-based nomogram to predict the effect of tubular microdiscectomy for lumbar disc herniation

Āsana for Back, Hips and Legs to Prevent Musculoskeletal Disorders among Dental Professionals: In-Office Yóga Protocol

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