Association between severity of pain, perceived stress and vagally-mediated heart rate variability in women with endometriosis

Moreira, Marcelo de França; Gamboa, Olga Lucía; Oliveira, Marco Aurélio Pinho

doi:10.1080/03630242.2021.1993423

Cited by 8 publications

(3 citation statements)

References 35 publications

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“…These studies found CTS patients with high anxiety and stress levels reported considerable improvement in their functional status, and their symptoms got worse with persistent stress, which is similar to our results. Moreover, our results are consistent with previous research that found that perceived stress is associated with increased pain intensity and disability in various chronic pain conditions, including low back pain [ 49 ], fibromyalgia [ 50 ], endometriosis [ 51 ], arthritis [ 52 ], migraine [ 53 ], multiple sclerosis [ 54 ], neuropathic pain, and a group of chronic overlapping pain conditions [ 55 ]. These conditions produce similar functional impairments, like CTS, which further supports our findings.…”

Section: Discussionsupporting

confidence: 92%

Perceived stress, coping strategies, symptoms severity and function status among carpal tunnel syndrome patients: a nurse-led correlational Study

Asal,

Atta,

Abdelaliem

et al. 2024

BMC Nurs

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Background Carpal tunnel syndrome (CTS) is a prevalent condition characterized by hand pain, tingling, and numbness. The severity of symptoms and functional status in CTS patients may be influenced by perceived stress and how individuals cope with it. However, scarce knowledge exists about the role of coping strategies as moderators in this relationship. Unfolding the role of perceived stress and coping strategies for CTS management will help the nurse to provide comprehensive and tailored nursing care. This will ultimately improve patient comfort, functionality, and quality of life. Purposes This study aimed to examine the role of coping strategies (adaptive and maladaptive) in the relationship between perceived stress and both symptoms severity and function status among those patients. Method We employed a multisite, correlational study design with moderation analysis. The study included 215 patients with CTS from neurosurgery outpatient clinics at three hospitals in Egypt. After obtaining their consent to participate, eligible participants completed anonymous, self-reported measures of perceived stress, the brief COPE inventory, and the Boston Carpal Tunnel Questionnaire. Demographic and biomedical data were also collected. The questionnaire took about 20 min to be completed. The data was collected over six months, starting in February 2023. Results The results showed that perceived stress, adaptive coping, and maladaptive coping were significant predictors of symptoms severity and functional status. Adaptive coping moderated the relationships between perceived stress and both symptoms severity and function status, while maladaptive coping did not. The interaction between perceived stress and adaptive coping explained a moderate effect on symptoms severity and function status after controlling for the main effects and the covariates. Conclusion This study explored the relationship between perceived stress, coping strategies, and outcomes in patients with CTS. The results indicate that nurses play a vital role in assessing and assisting patients to adopt effective coping strategies to manage perceived stress and alleviate symptoms and functional impairment. Moreover, the findings support the need for psychological interventions that address both perceived stress and coping strategies as a way to enhance the functioning status and quality of life of patients with CTS.

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Section: Discussionsupporting

confidence: 92%

Perceived stress, coping strategies, symptoms severity and function status among carpal tunnel syndrome patients: a nurse-led correlational Study

Asal,

Atta,

Abdelaliem

et al. 2024

BMC Nurs

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“…This scale allows patients to subjectively rate their pain, providing a straightforward and effective measure of the severity of their symptoms. This tool was validated for this population by previous studies [17][18][19][20]. This assessment was performed for each of the characteristics of pelvic pain, including dyspareunia, dysmenorrhea, nonmenstrual pelvic pain, dysuria, or dyschezia.…”

Section: Painmentioning

confidence: 99%

What Is Behind? Impact of Pelvic Pain on Perceived Stress and Inflammatory Markers in Women with Deep Endometriosis

Osaki,

Oliveira

2024

JCM

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Introduction/Objectives: Endometriosis affects 10% of women worldwide. It is noteworthy that this condition is often accompanied by pelvic pain and stress. Endometriosis is a debilitating gynecological condition where tissue similar to the uterine lining grows outside the uterus, often causing significant pain and reproductive issues. We aimed to study the relationship between the intensity of pelvic pain, and stress and inflammatory markers in women with deep endometriosis. Methods: This cross-sectional study analyzed women diagnosed with deep endometriosis through imaging, surgery, and/or biopsy. We assessed pain using the Numerical Rating Scale (NRS). Stress was assessed with the Perceived Stress Scale (PSS-10) questionnaire and the serum cortisol levels. Additionally, we analyzed inflammatory markers, including C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Results: Fifty-two women, with an average age of 37.8 ± 6.9 years, participated in this study. Forty-four percent of these participants demonstrated high levels of stress, as indicated by scores above 26 on the PSS-10. Those categorized with “high stress” on the PSS-10 questionnaire exhibited significantly higher pain levels compared to those with “low stress” (p < 0.05). Furthermore, patients experiencing more-severe pelvic pain (pain score > 7) had notably higher serum cortisol levels. Women with intense pelvic pain (scores above 7 on the NRS) had significantly elevated serum cortisol levels (Cohen’s d = 0.72; p = 0.018). Conclusions: A positive association was found between stress levels and the intensity of pelvic pain in women with deep endometriosis, suggesting an interconnection between emotional aspects and biological responses.

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“…In fact, changes in cortisol levels have been associated with pain intensity (negative correlation) in these conditions [ 22 , 23 ]. Concurrent with HPA-axis hormonal changes, patients with both syndromes simultaneously present changes in the autonomic nervous system [ 24 , 25 ]. Therefore, both EPS and CPBPS patients present several phenotypes, which may explain why the available therapies are not pan-effective.…”

Section: The Implications Of Symptom Identification In the Study Of C...mentioning

confidence: 99%

The Unmet Needs for Studying Chronic Pelvic/Visceral Pain Using Animal Models

et al. 2023

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The different definitions of chronic pelvic/visceral pain used by international societies have changed over the years. These differences have a great impact on the way researchers study chronic pelvic/visceral pain. Recently, the role of systemic changes, including the role of the central nervous system, in the perpetuation and chronification of pelvic/visceral pain has gained weight. Consequently, researchers are using animal models that resemble those systemic changes rather than using models that are organ- or tissue-specific. In this review, we discuss the advantages and disadvantages of using bladder-centric and systemic models, enumerating some of the central nervous system changes and pain-related behaviors occurring in each model. We also present some drawbacks when using animal models and pain-related behavior tests and raise questions about possible, yet to be demonstrated, investigator-related bias. We also suggest new approaches to study chronic pelvic/visceral pain by refining existing animal models or using new ones.

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Association between severity of pain, perceived stress and vagally-mediated heart rate variability in women with endometriosis

Cited by 8 publications

References 35 publications

Perceived stress, coping strategies, symptoms severity and function status among carpal tunnel syndrome patients: a nurse-led correlational Study

Perceived stress, coping strategies, symptoms severity and function status among carpal tunnel syndrome patients: a nurse-led correlational Study

What Is Behind? Impact of Pelvic Pain on Perceived Stress and Inflammatory Markers in Women with Deep Endometriosis

The Unmet Needs for Studying Chronic Pelvic/Visceral Pain Using Animal Models

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