Association between soil-transmitted helminthiasis and hemoglobin concentration in primary school children

Abstract

Objectives To determine the association between intestinal hel-minthiasis and hemoglobin (Hb) concentration and to observe theeffect of single dose albendazole treatment on Hb concentration.Methods An experimental study was carried out from March toJuly 2002 on primary school children at Suka Village, Tiga PanahSubdistrict, Karo Regency, North Sumatera Province. From 366children who suffered from helminthiasis, 113 were selected assubjects by simple random sampling. Subjects were treated with asingle oral dose of 400 mg albendazole. Hb concentration wasexamined using the cyanide method twice i.e., prior to and threemonths after treatment with albendazole.Results It was found that among 113 subjects, the prevalences ofAscaris lumbricoides, Trichuris trichiura, and mixed infestation were18.3%, 40.4%, and 41.3%, respectively, while the prevalence ofanemia was 33.0%. There was no significant difference in age,gender, nutritional status, and mean Hb concentration betweenchildren suffering from the different types of worm infestation(P>0.05). For each type of infestation, there were significant differ-ences in mean Hb concentration and anemia prevalence beforeand after treatment (P<0.05).Conclusions There was no difference between the Hb concen-trations of children suffering from Ascaris lumbricoides, Trichuristrichiura, and mixed-type worm infestations. Single dose 400 mgalbendazole was beneficial in increasing Hb concentration andreducing the occurrence of anemia

Prevalence and Knowledge of Soil-Transmitted Helminth Infections in Mandailing Natal, North Sumatera, Indonesia

“…Further, we also assessed the hygiene behaviour in those children. Similar to our earlier studies in other districts in North Sumatra province, the prevalence of STH infections remains high [3], [4], [5], [6], [7], [8], [9], [13], despite existing health promotion and education to reduce STH burden.…”

“…In areas with poor sanitation, the prevalence can reach as high as 80% [2]. In different districts in North Sumatra province, the prevalence of helminthiasis in suburban and rural areas have been reported from 87% in 2004, 84.6% in 2005, 64.3% in 2012 to 84.66% in 2015 [3], [4], [5], [6], [7], [8], [9]. Helminthiasis affects the nutritional status and cognitive function of the children, and in the long-term may interfere with their growth [10].…”

Efficacy of Albendazole-Pyrantel Pamoate Compared to Albendazole Alone for Trichuris trichiura Infection in Children: A Double Blind Randomised Controlled Trial

“…STH infections are associated with humans and may include Ascaris lumbricoides, Trichuris trichiura and hookworm ( Ancylostoma duodenale, Necator americanus) which are reported to have infected more than a quarter of the world’s population. The World Health Organization (WHO) reported that more than two billion people have been infected with Ascaris lumbricoides , 750 million with Trichuris trichiura and another 900 million with hookworm ( 2 , 3 ). –…”