Association between Spinal Cord Injury and Alcohol Dependence: A Population-Based Retrospective Cohort Study

Chuang, Ching-Hui; Chen, Po‐Cheng; Bai, Chyi‐Huey; Wu, Yi Lin; Tsai, Ming-Chao; Li, Chieh-Yu

doi:10.3390/jpm12030473

Cited by 3 publications

(1 citation statement)

References 36 publications

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“…This has refocused the concern on preventing and treating complications involving medical care and hospitalization to improve the quality of life of these patients [ 3 ]. The impact of this pathology is broad, ranging from psychological [ 4 , 5 ] to relating to the social environment [ 6 ], chronic pain [ 7 ], and sexual/reproductive disturbances [ 8 ]. This can lead to damage and malfunctioning in various organs secondary to the establishment of pathological phenomena such as obesity, diabetes, dyslipidemia, and cardiovascular disorders [ 9 ], on which, in recent years, research has focused, to the detriment of other medical problems [ 10 , 11 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Systemic and Pulmonary Inflammation/Oxidative Damage: Implications of General and Respiratory Muscle Training in Chronic Spinal-Cord-Injured Patients

Araneda,

Rosales-Antequera,

Contreras-Briceño

et al. 2023

Biology

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Chronic spinal cord injury affects several respiratory-function-related parameters, such as a decrease in respiratory volumes associated with weakness and a tendency to fibrosis of the perithoracic muscles, a predominance of vagal over sympathetic action inducing airway obstructions, and a difficulty in mobilizing secretions. Altogether, these changes result in both restrictive and obstructive patterns. Moreover, low pulmonary ventilation and reduced cardiovascular system functionality (low venous return and right stroke volume) will hinder adequate alveolar recruitment and low O2 diffusion, leading to a drop in peak physical performance. In addition to the functional effects described above, systemic and localized effects on this organ chronically increase oxidative damage and tissue inflammation. This narrative review describes both the deleterious effects of chronic spinal cord injury on the functional effects of the respiratory system as well as the role of oxidative damage/inflammation in this clinical context. In addition, the evidence for the effect of general and respiratory muscular training on the skeletal muscle as a possible preventive and treatment strategy for both functional effects and underlying tissue mechanisms is summarized.

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Section: Introductionmentioning

confidence: 99%

Systemic and Pulmonary Inflammation/Oxidative Damage: Implications of General and Respiratory Muscle Training in Chronic Spinal-Cord-Injured Patients

Araneda,

Rosales-Antequera,

Contreras-Briceño

et al. 2023

Biology

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Exploring lifestyle components and associated factors in newly injured individuals with spinal cord injury

Haldemann,

Stojic,

Eriks-Hoogland

et al. 2024

Spinal Cord

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Study design Cross-sectional analysis from the Inception Cohort of the Swiss Spinal Cord Injury Study (SwiSCI). Objectives To describe five lifestyle components in newly injured individuals with spinal cord injury (SCI), explore co-occurrence of these components, and identify associated personal and clinical factors. Settings Initial rehabilitation stay following traumatic and non-traumatic SCI. Methods Lifestyle components including overweight/obesity, low diet score, physical inactivity, smoking, and alcohol consumption were used independently and to calculate a composite lifestyle score. Analyses were conducted using descriptive statistics, co-occurrence analysis, and multivariate logistic regression. Results We included 251 individuals, of whom 77.7% were male, 73.7% suffered from traumatic SCI, and 59.8% had paraplegia. The median age was 51 years (IQR 36–64). Approximately twelve weeks after the injury, more than two-thirds of the study population met the criteria for overweight/obesity, and consumed insufficient amounts of fruits and vegetables, and excessive amounts of meat. Alcohol was consumed by 85.3% of individuals, and 26.8% were current smokers. Almost all study participants met the physical activity guidelines (90 min of moderate to strenuous activity physical activity per week). One-quarter of study participants experienced the co-occurrence of overweight/obesity, low diet score and alcohol consumption. Female sex, younger age and higher education were associated with healthier lifestyle components. Conclusion Despite methodological limitations, this study underscores the complexities of healthy lifestyle adherence among individuals newly injured with SCI. It highlights the necessity of improving and implementing screening strategies throughout the continuum of SCI care as early as possible following the trauma.

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The Influence of Adolescent Health-related Behaviors on Degenerative Low Back Pain Hospitalizations and Surgeries in Adulthood

Vaajala,

Teuho,

Liukkonen

et al. 2024

Spine

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Study Design. Retrospective longitudinal study Objective. This study aims to investigate the influence of adolescent health-related behaviors (physical activity, high BMI, drunkenness, smoking), self-reported chronic disease, and low socioeconomic status (SES) on the development of low back pain requiring hospitalization or surgery. Summary of Background Data. The baseline data were surveys gathered biennially in 1981-1997 (the Adolescent Health and Lifestyle Survey) and individually linked with outcome data, degenerative low back pain hospitalizations, and spine surgeries retrieved from the Care Register for Health Care. A total of 47 724 participants were included. Explanatory variables included physical activity, high BMI, smoking, monthly drunkenness, chronic diseases, and family SES. Methods. A logistic regression model was used to analyze the influence of adolescent health-related behaviors (physical activity, high BMI, drunkenness, smoking), self-reported chronic disease, and low socioeconomic status (SES) on degenerative low back pain hospitalization, lumbar disc herniation (LDH) hospitalization and/or spine surgery. Covariates were selected using directed acyclic graphs (DAGs). Results. A total of 5538 participants had degenerative low back pain hospitalizations, 2104 had LDH hospitalizations, and 913 had spinal surgery over an average of 27-years follow-up. High BMI (aOR 1.25, CI 1.12-1.38), smoking (aOR 1.53, CI 1.43-1.62), monthly drunkenness (aOR 1.17, CI 1.10-1.26), and chronic diseases (aOR 1.47, CI 1.35-1.61) in adolescence increased the odds of hospitalizations during follow-up. In addition, high BMI (aOR 1.37, CI 1.09-1.72), smoking (aOR 1.40, CI 1.21-1.61), and monthly drunkenness (aOR 1.19, CI 1.01-1.39) increased the odds of spine surgeries. Conclusions. We found that smoking, high BMI, monthly drunkenness, chronic diseases, and low family SES in adolescence increased the likelihood of degenerative low back pain hospitalizations in adulthood. In addition, high BMI, smoking, and monthly drunkenness in adolescence increased the odds of spinal surgeries.

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Association between Spinal Cord Injury and Alcohol Dependence: A Population-Based Retrospective Cohort Study

Cited by 3 publications

References 36 publications

Systemic and Pulmonary Inflammation/Oxidative Damage: Implications of General and Respiratory Muscle Training in Chronic Spinal-Cord-Injured Patients

Systemic and Pulmonary Inflammation/Oxidative Damage: Implications of General and Respiratory Muscle Training in Chronic Spinal-Cord-Injured Patients

Exploring lifestyle components and associated factors in newly injured individuals with spinal cord injury

The Influence of Adolescent Health-related Behaviors on Degenerative Low Back Pain Hospitalizations and Surgeries in Adulthood

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