Association between stressful life events and autoimmune diseases: A systematic review and meta-analysis of retrospective case–control studies

Porcelli, Brunetta; Pozza, Andrea; Bizzaro, Nicola; Fagiolini, Andrea; Costantini, Maria Cristina; Terzuoli, Lucia; Ferretti, Fabio

doi:10.1016/j.autrev.2015.12.005

Cited by 106 publications

(35 citation statements)

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“…The relationship between traumatic stress and organic symptoms is well established in the literature (Afari et al, ; Passos et al, ; Porcelli et al, ; Rosenbaum et al, ). Various neuroanatomical structures are involved in the pathogenesis of posttraumatic stress disorder (PTSD), but only a subgroup of individuals who experience trauma develop the disorder.…”

Section: Introductionmentioning

confidence: 93%

A comparison of physical comorbidities in patients with posttraumatic stress disorder developed after a terrorist attack or other traumatic event

Ferretti

Pozza

Bossini

et al. 2019

J of Neuroscience Research

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No study investigated whether the presence of specific medical comorbidities is associated with the type of traumatic event, in particular with terrorist attack (TA). In a group of subjects with posttraumatic stress disorder (PTSD), the current study investigated the association between the types of traumatic event (TA vs. other traumatic event [OTE]) and medical comorbidities, controlling for sex and PTSD duration. The Mini International Neuropsychiatric Interview, the Clinician‐Administered PTSD Scale, and the Davidson Trauma Scale were administered to 84 subjects diagnosed with PTSD. Thirty‐nine were victims of TA and 45 victims of OTE. TA was associated with higher prevalence of neoplasms (β = 2.60, p = 0.02). Females were more protected than males from circulatory system comorbidities (β = 1.47, p = 0.04), while PTSD duration was associated with higher prevalence of such comorbidities (β = 0.005, p = 0.01). Females showed a higher prevalence of neoplasms than males (β = 2.50, p = 0.02). Female sex was protective against metabolic syndrome (β = −1.79, p = 0.02). Patients with PTSD due to TA and female patients should be considered for their higher prevalence of neoplasms, while male patients and those with higher symptom duration should be monitored for circulatory disease and metabolic syndrome. Symptom duration might be associated with circulatory and metabolic disease. Implications for tailored and timely psychopharmacological and psychotherapeutic intervention for PTSD are discussed focusing on these specific medical comorbidities.

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Section: Introductionmentioning

confidence: 93%

A comparison of physical comorbidities in patients with posttraumatic stress disorder developed after a terrorist attack or other traumatic event

Ferretti

Pozza

Bossini

et al. 2019

J of Neuroscience Research

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“…Stress has been implicated as a risk factor in cardiovascular disease (Richardson et al,15 2012), the progression of HIV/AIDS (Remor et al, 2007), wound healing response (Broadbent et al, 2012), upper respiratory infections (Pedersen et al, 2010) and autoimmune diseases (Porcelli et al, 2016). Stress may directly interfere with the regulation of immune and inflammatory processes.…”

Section: Introductionmentioning

confidence: 99%

How financial strain affects health: Evidence from the Dutch National Bank Household Survey

Prentice

McKillop

French

2017

Social Science & Medicine

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The mechanisms by which financial strain affects health are not well understood. In this paper, we conduct a longitudinal mediation analysis of the Dutch National Bank 5Household Survey. To quantify the relative importance of biological and nonbiological pathways from financial strain to health, we consider smoking, heavy drinking and being overweight as plausible behavioural responses to financial strain but find that only 4.9% of the response of self-reported health to financial strain is mediated by these behaviours. Further analysis indicates that although financial strain increases 10 impulsivity this has little effect on unhealthy behaviours. Economic stresses therefore appear to be distinct from other forms of stress in the relatively minor influence of nonbiological pathways to ill-health.

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“…Aunque un análisis sobre esta cuestión sobrepasa los objetivos y límites del presente estudio, los sucesos vitales se han asociado a la salud física en general (Holmes y David, 1989;Sandín, 1989Sandín, , 1993Sandín, , 2008, la sintomatología somática (Sandín, Chorot, Santed, y Valiente, 2002), y la mayor parte de las perturbaciones y enfermedades físicas, incluidas las enfermedades cardiovasculares (Bernston, Patel, y Steward, 2017;Chorot y Sandín, 1994;Sandín, Chorot, Santed, y Jiménez, 2009), el cán-cer (Chorot y Sandín, 1994;Heikkinen et al, 2017;, los trastornos gastrointestinales (Tobón, Sandín, y Vinaccia, 2006;Tobón, Vinaccia, y Sandín, 2003), la diabetes y en general las enfermedades autoinmunes y la resistencia a la enfermedad (Holmes y David, 1989;Porcelli et al, 2016;.…”

Section: Introductionunclassified

Cuestionario de Sucesos Vitales (CSV): Estructura factorial, características psicométricas y datos normativos

Sandín¹,

Chorot²

2017

RPPC

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Abstract:The aim of the present study was to validate the Life Events Questionnaire (Cuestionario de Sucesos Vitales, CSV). Two large and independent samples were used (age range 19 to 67 years). A protocol including the CSV, the PANAS Scales, the DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure−Adult, the Anxiety Scale (EA), the Depression Questionnaire (CD), and the Health Questionnaire (CS) was completed on two separate occasions (with a 6-month interval). Exploratory and confi rmatory factor analyses revealed a 7-factor structure of the CSV, suggesting seven stress-relevant psychosocial domains. Scores on the questionnaire were predictive of elevated levels of psychopathology, anxiety, depression, and diseases assessed 6 months later, after controlling for the effect of negative and positive affectivity, age and gender. Evidence of reliability, normative data, and validity of the CSV is also reported. We conclude that the CSV provides a suitable measure for psychosocial stress assessment.Keywods: Life Events Questionnaire; CSV; psychosocial stress; negative life events; psychopathology; anxiety; depression; disease.Resumen: El objetivo del estudio fue validar el Cuestionario de Sucesos Vitales (CSV). Se utilizaron dos muestras amplias e independientes (rango de edad: 19-67 años). Se aplicó un protocolo en dos momentos temporales (separados por 6 meses) que incluía el CSV, las escalas PANAS de afecto positivo y negativo, el DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure−Adult), la Escala de Ansiedad (EA), el Cuestionario de Depresión (CD), y el Cuestionario de Salud (CS). Los análisis factoriales exploratorios y confi rmatorios revelaron una estructura de 7 factores que sugieren siete dimensiones psicosociales relevantes al estrés. El CSV predijo las puntuaciones en psicopatología, ansiedad, depresión y enfermedades, evaluadas 6 meses más tarde, tras controlar el efecto de la afectividad negativa y positiva, la edad y el género. También se proporciona evidencia de fi abilidad, datos normativos y validez del CSV. Se concluye que el CSV constituye una herramienta adecuada para la evaluación del estrés psicosocial.Palabras clave: Cuestionario de Sucesos Vitales; CSV; estrés psicosocial; sucesos vitales negativos; psicopatología; ansiedad; depresión; enfermedad.a IntroducciónAparte de la confusión (no sólo popular sino también científi ca) que suele existir en la interpretación sobre lo que es el estrés, su conceptualización ha venido enfatizando diferentes enfoques o puntos de vista, entre los que se incluyen la consideración del estrés como una respuesta (p.ej., activación del sistema hipotálamo-hipó-fi so-corticosuprarrenal), como un estímulo (p.ej., un suceso vital), o como un proceso de interacción entre el estímulo y la respuesta (p.ej., aproximaciones mediacionales o interaccionales del estrés) (véase Sandín, 2009). Los enfoques del estrés basados en el estímulo han tenido gran repercusión sobre la psicología clínica en las últimas décadas, siendo el más infl uyente el conocido como «enfoque ...

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Association between stressful life events and autoimmune diseases: A systematic review and meta-analysis of retrospective case–control studies

Cited by 106 publications

References 46 publications

A comparison of physical comorbidities in patients with posttraumatic stress disorder developed after a terrorist attack or other traumatic event

A comparison of physical comorbidities in patients with posttraumatic stress disorder developed after a terrorist attack or other traumatic event

How financial strain affects health: Evidence from the Dutch National Bank Household Survey

Cuestionario de Sucesos Vitales (CSV): Estructura factorial, características psicométricas y datos normativos

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