Association between sun-exposure, smoking behaviour and plasma antioxidant levels with the different manifestation of skin ageing signs between Japanese and German women—A pilot study

Perner, D.; Vierkötter, Andrea; Sugiri, Dorothee; Matsui, Mary S.; Ranft, Ulrich; Esser, Charlotte; Etheve, Stéphane; Góralczyk, Regina; Kaneko, Noriyo; Yamamoto, Ai; Morita, Akimichi; Krutmann, Jean; Krämer, Ursula

doi:10.1016/j.jdermsci.2011.02.010

Cited by 25 publications

(20 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some types of wrinkles were shown to appear approximately 15 years earlier in French than in Japanese women [103]. Similar differences were observed between German and Japanese women [106]. If dermal adipocytes are involved in the skin aging processes, these differences should be at least partly connected with ethnic variations in dWAT content.…”

Section: Introductionmentioning

confidence: 84%

Skin aging: are adipocytes the next target?

Kruglikov¹,

Scherer

2016

Aging

View full text Add to dashboard Cite

Dermal white adipose tissue (dWAT) is increasingly appreciated as a special fat depot. The adipocytes in this depot exert a variety of unique effects on their surrounding cells and can undergo massive phenotypic changes. Significant modulation of dWAT content can be observed both in intrinsically and extrinsically aged skin. Specifically, skin that has been chronically photo-damaged displays a reduction of the dWAT volume, caused by the replacement of adipocytes by fibrotic structures. This is likely to be caused by the recently uncovered process described as “adipocyte-myofibroblast transition” (AMT). In addition, contributions of dermal adipocytes to the skin aging processes are also indirectly supported by spatial correlations between the prevalence of hypertrophic scarring and the appearance of signs of skin aging in different ethnic groups. These observations could elevate dermal adipocytes to prime targets in strategies aimed at counteracting skin aging.

show abstract

Section: Introductionmentioning

confidence: 84%

Skin aging: are adipocytes the next target?

Kruglikov¹,

Scherer

2016

Aging

View full text Add to dashboard Cite

show abstract

“…7 There are also some studies that report the characteristics of photoaging in Japanese people. Comparison of age-related changes of photoaging in Japanese females and Caucasian or other Asian females revealed that Caucasians are more susceptible to wrinkles or skin sagging than Japanese, 8,9 and there are some differences in characteristics of photoaging even among Asian people. 10 However, the relationship between UV exposure and photoaging has rarely been demonstrated by interventional studies in Japan.…”

Section: Mizuno Et Almentioning

confidence: 97%

“…9 All photoaging symptoms are not necessarily more severe in Caucasians than in Japanese. There was a dose-dependent decrease in the number of spots although no changes in wrinkles were seen during the 18-month study period.…”

Section: Susceptibility To Photoaging In Japanese Populationmentioning

confidence: 99%

The effects of continuous application of sunscreen on photoaged skin in Japanese elderly people—the relationship with the usage

Mizuno

Kunimoto

Seigan

et al. 2016

Journal of Dermatological Science

View full text Add to dashboard Cite

“…Interstitial deletion is another source for producing fusions (Figure 2C). One example is TMPRSS2-ERG , which is frequently found in prostate cancer [23, 24]. Other cases include MLL-FOXR1 and PAFAH1B2-FOXR1 , found exclusively in neuroblastoma [25].…”

Section: Production Of Chimeric Rnasmentioning

confidence: 99%

Intergenically Spliced Chimeric RNAs in Cancer

Jia

Xie

2016

Trends in Cancer

View full text Add to dashboard Cite

Gene fusions and their encoded products (fusion RNAs and proteins) are viewed as one of the hallmarks of cancer. Traditionally, they were thought to be generated solely by chromosomal rearrangements. However, recent discoveries of trans-splicing and cis-splicing events between neighboring genes, suggest that there are other mechanisms to generate chimeric fusion RNAs without corresponding changes in DNA. In addition, chimeric RNAs have been detected in normal physiology, complicating the use of fusions in cancer detection and therapy. On the other hand, “intergenically spliced” fusion RNAs represent a new repertoire of biomarkers and therapeutic targets. Here, we review current knowledge on chimeric RNAs and implications for cancer detection and treatment, and discuss outstanding questions for the advancement of the field.

show abstract

Association between sun-exposure, smoking behaviour and plasma antioxidant levels with the different manifestation of skin ageing signs between Japanese and German women—A pilot study

Cited by 25 publications

References 10 publications

Skin aging: are adipocytes the next target?

Skin aging: are adipocytes the next target?

The effects of continuous application of sunscreen on photoaged skin in Japanese elderly people—the relationship with the usage

Intergenically Spliced Chimeric RNAs in Cancer

Contact Info

Product

Resources

About