Association between the cashmere production performance, milk production performance, and body size traits and polymorphism of
            <i>COL6A5</i>
            and
            <i>LOC102181374</i>
            genes in Liaoning cashmere goats

Qin, Yuting; Gu, Min; Xu, Yanan; Dou, Xingtang; Han, Dongyi; Lin, Guangyu; Wang, Lingling; Wang, Zhanhong; Wang, Jiaming; Sun, Yanyan; Wu, Yanzhi; Chen, Rui; Qiao, Yan; Zhang, Qiu; Li, Qian; Wang, Xiaowei; Xu, Zhiguo; Yao, Cong; Chen, Jing; Wang, Zeying

doi:10.1080/10495398.2022.2155177

Cited by 3 publications

(2 citation statements)

References 48 publications

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“…According to the PIC values, g.14135 A>C, g.14247 C>A, g.14305 C>T, and g.16800 G>A loci were low polymorphic in Congjiang Xiang pigs (PIC < 0.25). We speculate that the reasons for these results may be related to the intensity of artificial selection that may have affected allele frequencies and genotype frequencies (Zhang et al, 2023).…”

Section: Discussionmentioning

confidence: 95%

Genetic polymorphisms in SIRT5 gene and their association with carcass traits in Congjiang Xiang pigs

Zhang,

Wang,

Zhao

et al. 2024

Revista Brasileira De Zootecnia

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This study was conducted to investigate the polymorphism of the silence information regulator 5 (SIRT5) gene in 103 Congjiang Xiang pigs from Southwest China. We searched for SNP (single nucleotide polymorphism) loci of SIRT5 gene through sequence alignment and PCR. We obtained nine SNP loci: g.14135 A>C (intron 6), g.14247 C>A (intron 6), g.14305 C>T (exon 7), g.14335 C>T (exon 7), g.16603 T>C (intron 7), g.16613 T>C (intron 7), g.16800 G>A (intron 7), g.16812 C>G (intron 7), and g.16916 A>G (exon 8). Further analysis of SNP genotypes associated with the carcass traits of skin thickness, backfat thickness, and eye muscle area was carried out in pigs. We found that the genotypes g.14305 C>T (CC) and g.16812 C>G (CG) had certain advantages for improving the carcass traits of Congjiang Xiang pigs. The haplotype combination of the SIRT5 gene that improved skin thickness was H2H3:CCGGCTCA. These results may provide empirical support for molecular-based breeding of carcass traits in Congjiang Xiang pigs.

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Section: Discussionmentioning

confidence: 95%

Genetic polymorphisms in SIRT5 gene and their association with carcass traits in Congjiang Xiang pigs

Zhang,

Wang,

Zhao

et al. 2024

Revista Brasileira De Zootecnia

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“…Transcriptomic analysis of cashmere goats under different photoperiods revealed differentially expressed miRNAs and mRNAs affecting the growth of cashmere [ 15 ]. In addition, high-throughput sequencing studies have enabled the identification of cashmere shape characteristics in cashmere goats [ 16 ], the identification of key genes and proteins of different cashmere types [ 17 , 18 , 19 , 20 ], and the analysis of goats’ milk production traits [ 21 ]. This technology can comprehensively reveal the molecular regulatory network and mechanism of cashmere shape in cashmere goats from a macroscopic and multidimensional perspective, providing an important theoretical basis for in-depth research on cashmere goats.…”

Section: Introductionmentioning

confidence: 99%

Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats’ Follicle Development Assessed by Whole-Transcriptome Sequencing Technology

Gao

Song

Fei

et al. 2023

Animals

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Cashmere, a keratinised product of secondary hair follicles (SHFs) in cashmere goats, holds an important place in international high-end textiles. However, research on the complex molecular and signal regulation during the development and growth of hair follicles (HFs), which is essential for the development of the cashmere industry, is limited. Moreover, increasing evidence indicates that non-coding RNAs (ncRNAs) participate in HF development. Herein, we systematically investigated a competing endogenous RNA (ceRNA) regulatory network mediated by circular RNAs (circRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs) in skin samples of cashmere goat embryos, using whole-transcriptome sequencing technology. We obtained 6468, 394, and 239 significantly differentially expressed mRNAs, circRNAs, and miRNAs, respectively. These identified RNAs were further used to construct a ceRNA regulatory network, mediated by circRNAs, for cashmere goats at a late stage of HF development. Among the molecular species identified, miR-184 and fibroblast growth factor (FGF) 10 exhibited competitive targeted interactions. In secondary HF dermal papilla cells (SHF-DPCs), miR-184 promotes proliferation, inhibits apoptosis, and alters the cell cycle via the competitive release of FGF10. This study reports that FGF10 and its interaction with ncRNAs significantly affect SHF-DPCs, providing a reference for research on the biology of HFs in cashmere goats and other mammals.

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Correlation and regression analysis of FA2H and ELOVL3 functional genes for cashmere fineness with production performance in Liaoning cashmere goat

Li,

Kong,

et al. 2024

Journal of Genetic Engineering and Biotechnology

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Association between the cashmere production performance, milk production performance, and body size traits and polymorphism of COL6A5 and LOC102181374 genes in Liaoning cashmere goats

Cited by 3 publications

References 48 publications

Genetic polymorphisms in SIRT5 gene and their association with carcass traits in Congjiang Xiang pigs

Genetic polymorphisms in SIRT5 gene and their association with carcass traits in Congjiang Xiang pigs

Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats’ Follicle Development Assessed by Whole-Transcriptome Sequencing Technology

Correlation and regression analysis of FA2H and ELOVL3 functional genes for cashmere fineness with production performance in Liaoning cashmere goat

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