Association between the gut microbiota and diet: Fetal life, early childhood, and further life

Kashtanova, Daria A.; Popenko, Anna; Ткачева, О. Н.; Tyakht, Alexander; Alexeev, Dmitry; Boytsov, S. А.

doi:10.1016/j.nut.2015.12.037

Cited by 129 publications

(97 citation statements)

References 100 publications

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“…For example, the Bacteroides enterotype is found in individuals consuming fat and protein‐rich diet, whereas the Prevotella enterotype is often present in the gut microbiota of persons eating a fibre’s rich diet. It has been estimated that about 90–95% of dietary fats are absorbed in the small intestine, which may explain why fats dramatically impact the gut microbiota composition . High‐fat diets are indeed associated with low SCFAs and low Bifidobacterium concentrations .…”

Section: Dietmentioning

confidence: 99%

“…High‐fat diets are indeed associated with low SCFAs and low Bifidobacterium concentrations . Mice fed a palm oil‐based diet show an increase in the ratio of Firmicutes to Bacteroidetes , an elevation in Clostridium species , and a reduction of overall microbiota diversity . Proteins are an integral part of a healthy diet, but it has been shown that the relationship between protein intake and health follows a U‐shaped curve .…”

Section: Dietmentioning

confidence: 99%

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The mutual interplay of gut microbiota, diet and human disease

2020

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The intestinal milieu harbours the gut microbiota, consisting of a complex community of bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an endowment of cells and genes more numerous than its own. In the last 10 years, mounting evidence has highlighted the prominent influence of the gut mutualistic bacterial communities on human health. Microbial colonization occurs alongside with immune system development and plays a role in intestinal physiology. The community of the gut microbiota does not undergo significant fluctuations throughout adult life. However, bacterial infections, antibiotic treatment, lifestyle, surgery and diet might profoundly affect it. Gut microbiota dysbiosis, defined as marked alterations in the amount and function of the intestinal microorganisms, is correlated with the aetiology of chronic noncommunicable diseases, ranging from cardiovascular, neurologic, respiratory and metabolic illnesses to cancer. In this review, we focus on the interplay among gut microbiota, diet and host to provide a perspective on the role of microbiota and their unique metabolites in the pathogenesis and/or progression of various human disorders. We discuss interventions based on microbiome studies, that is faecal microbiota transplantation, probiotics and prebiotics, to introduce the concept that correcting gut dysbiosis can ameliorate disease symptoms, thus offering a new approach towards disease treatment.

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Section: Dietmentioning

confidence: 99%

Section: Dietmentioning

confidence: 99%

The mutual interplay of gut microbiota, diet and human disease

2020

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“…Anti-inflammatory properties exist at the placental bed which protects the fetus from rejection, yet the mucosal surfaces of the gut and other tissues experience a low-grade inflammation with rising levels of pro-inflammatory cytokines and white cells as the pregnancy advances (Koren et al, 2012). When conditions like maternal obesity, gestational diabetes or a leaky gut shift the maternal inflammatory state from a physiologic to an excessive level, vascular dysfunction of the placental tissue can develop leading to deleterious effects such as fetal growth restriction and preeclampsia (Kashtanova et al, 2016; Kim, Romero, Chaemsaithong, & Kim, 2015). Gut microbes found in amniotic fluid of women who experienced preterm premature rupture of membranes suggest that the gut microbiome could play a role in intrauterine infections (DiGiulio et al, 2010).…”

Section: Immunologic Changes Of the Gut Microbiome In Pregnancymentioning

confidence: 99%

“…Such a diet promotes excess weight gain and a dysbiotic gut and is associated with adverse maternal and child health outcomes (Dunlop et al, 2015; Morrison & Regnault, 2016). Conversely, certain dietary nutrients, namely low-fat protein (for instance beans, skinless chicken, lean beef), organic proteins and produce (which reduces exposure to dietary antibiotics and pesticides), unsaturated fatty acids (for instance in canola and olive oils, flaxseeds, and salmon), whole grains, and certain strains of probiotics have been found to promote a healthy gut microbiome, enhance intestinal integrity and reduce excessive systemic inflammation (Griffin, 2015; Kashtanova et al, 2016). Short chain fatty acids (SCFA), such as acetate, propionate and butyrate, are byproducts of fiber fermentation called prebiotics and serve as an energy source to intestinal epithelial cells and enhance the connections between these cells (David et al, 2014).…”

Section: Factors That Can Modify the Gut Microbiomementioning

confidence: 99%

The Maternal Gut Microbiome During Pregnancy

Edwards

Cunningham

Dunlop

et al. 2017

McN: The American Journal of Maternal/Child Nursing

155

115

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The gut microbiome is a critical component of an individual’s metabolism and overall health. The prenatal period is marked by unique inflammatory and immune changes that alter maternal gut function and bacterial composition as the pregnancy advances. The composition of the maternal gut microbiome contributes to obstetric outcomes with long-term health sequelae for mother and child. Estrogen and progesterone also impact gut function, especially during the prenatal period. These physiologic changes in pregnancy allow for adjustments in maternal metabolism and weight necessary to support the pregnancy. This article will review the normal hormonal, metabolic and immunologic changes to the maternal gut microbiome throughout the prenatal period, in addition to relevant implications for nurses providing care for pregnant women.

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“…Other studies have demonstrated that the mode of delivery, vaginal versus caesarian section, as well as parental decisions regarding breast- or formula-feeding, can influence the establishment the infant’s gut microbiota, affecting both the diversity and richness of the microbial community (4–6). In addition, there appears to be another important developmental transition that coincides with weaning.…”

Section: Introductionmentioning

confidence: 99%

Social Influences on Prevotella and the Gut Microbiome of Young Monkeys

et al. 2017

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Objective Our aim was to evaluate the bacterial profiles of young monkeys as they were weaned into peer groups with a particular focus on Prevotella, an important taxon in both human and nonhuman primates. The weaning of infants and increased social contact with peers is a developmental stage that is likely to affect the gut microbiome. Methods Gut bacteria were assessed in 63 rhesus monkeys living in social groups comprised of 4–7 individuals. Two groups were assessed prospectively on Day 1 and 2 weeks after rehousing away from the mother and group formation. Ten additional groups were assessed at 2 weeks after group establishment. Fecal genomic DNA was extracted and 16S ribosomal RNA sequenced by Illumina MiSeq (5 social groups) and 454-amplicon pyrosequencing (7 social groups). Results Combining weaned infants into small social groups led to a microbial convergence by 2 weeks (p<.001). Diversity analyses indicated more similar community structure within peer groups than across groups (p<.01). Prevotella was the predominant taxon and its abundance differed markedly across individuals. Indices of richness, microbial profiles and less abundant taxa were all associated with the Prevotella levels. Functional KEGG analyses suggested corresponding shifts in metabolic pathways. Conclusions The formation of small groups of young rhesus monkeys was associated with significant shifts in the gut microbiota. The profiles were closely associated with the abundance of Prevotella, a predominant taxon in the rhesus monkey gut. Changes in the structure of the gut microbiome are likely to induce differences in metabolic and physiologic functioning.

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Association between the gut microbiota and diet: Fetal life, early childhood, and further life

Cited by 129 publications

References 100 publications

The mutual interplay of gut microbiota, diet and human disease

The mutual interplay of gut microbiota, diet and human disease

The Maternal Gut Microbiome During Pregnancy

Social Influences on Prevotella and the Gut Microbiome of Young Monkeys

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