Association Between Timed Up‐and‐Go and Memory, Executive Function, and Processing Speed

Donoghue, Orna A.; Horgan, N Frances; Savva, George M.; Cronin, Hilary; O’Regan, Claire; Kenny, Rose Anne

doi:10.1111/j.1532-5415.2012.04120.x

Cited by 136 publications

(134 citation statements)

References 31 publications

Supporting

Mentioning

118

Contrasting

Order By: Relevance

“…12,13 Greene and colleagues focused on change in test results over time in 189 community dwelling older adults. 12,13 They reported that TUG and the BBS scores were not significantly associated with CD after 2 years follow-up, but rather the change from baseline to follow-up in TUG parameters was independently and significantly associated with CD. It is possible that in our population the stroke may have triggered or unmasked underlying neurodegenerative processes.…”

Section: Strokementioning

confidence: 99%

See 1 more Smart Citation

Gait Measures as Predictors of Poststroke Cognitive Function

Assayag

Shenhar‐Tsarfaty

Korczyn

et al. 2015

Stroke

View full text Add to dashboard Cite

Stroke considerably increases the risk of cognitive decline (CD) and dementia, with prevalence rates ranging from 24% to 33.3% within 5 years from stroke onset. In many cases, the cognitive decline develops abruptly, while in others, the decline develops insidiously over months or years at a rate which far exceeds the expected decline in this age group. 1,2After a stroke, patients frequently experience a spectrum of neuropsychological and motor deficits that can significantly interfere with their cognitive, communicative, and motor functions, resulting in impaired activities and function. Identifying those at higher risk of developing cognitive impairment has implications for the early initiation of treatment and for monitoring disease progression.Slowing of motor function is commonly observed with aging and is more pronounced in cognitively impaired individuals.3 Gait changes predict dementia as much as 6 to 10 years later 4 and may also precede the onset of even mild cognitive impairment, 4 which may occur as much as 12 years before the clinical presentation of cognitive changes. Moreover, the combination of motor and cognitive changes apparently is a stronger predictor of dementia than cognitive changes alone.6 Although the mechanisms of these motorcognitive interactions are not fully understood, subclinical pathological changes caused by cerebrovascular disease may Background and Purpose-Patients with stroke are at risk for developing cognitive impairment. We tested whether the assessment of balance and gait can enhance the prediction of long-term cognitive outcome in stroke survivors. Methods-Participants were patients with first-ever, mild-moderate ischemic stroke or transient ischemic attack from the Tel Aviv Brain Acute Stroke Cohort (TABASCO) study, a large prospective cohort study, who underwent 3-T MRI and were followed for ≥2 years using neurological, neuropsychological, and mobility examinations 6, 12, and 24 months after the index event. Results-Data were available for 298 patients (age: 66.7±9.6 years). Forty-six participants (15.4%) developed cognitive decline (CD) over the 2 years of follow-up. The CD group and cognitively intact group did not differ in their neurological deficits or in their infarct volume or location. Nonetheless, 6 months after stroke, the Timed Up and Go test took longer in those who later developed CD (P<0.001). Additionally, the CD group also had lower Berg Balance Scale scores (P<0.001), slower gait (P<0.001), and fewer correct answers during dual-task walking (P=0.006). Separate analyses of the patients with transient ischemic attack revealed similar results. Multivariate regression analysis showed that Timed Up and Go times >12 s at 6 months after stroke/transient ischemic attack was a significant independent risk marker of CD 24 months after stroke (odds ratio=6.07, 95% confidence interval: 1.36-27.15). Conclusions-These

show abstract

Section: Strokementioning

confidence: 99%

“…This relationship can be explained by the idea that the TUG relies on the interplay between attention, executive function, and motor processing functions. 5,12,15 Moreover, dual-task during gait may be a marker of the efficiency of the central integration of multiple cognitive domains needed for this complex task.…”

Section: Strokementioning

confidence: 99%

Gait Measures as Predictors of Poststroke Cognitive Function

Assayag

Shenhar‐Tsarfaty

Korczyn

et al. 2015

Stroke

View full text Add to dashboard Cite

show abstract

“…Our findings build on previous research in several ways. First, studies in samples without serious mental illness found a similar association between slower TGUG and poorer performance on speed of processing tests (Donoghue et al, 2012; Herman, Giladi, & Hausdorff, 2011) and memory tests (Donoghue et al, 2012). Second, after adjusting for covariates (including age), Donoghue et al (2012) also reported significant associations between TGUG time and speed of processing.…”

Section: Discussionmentioning

confidence: 92%

“…First, studies in samples without serious mental illness found a similar association between slower TGUG and poorer performance on speed of processing tests (Donoghue et al, 2012; Herman, Giladi, & Hausdorff, 2011) and memory tests (Donoghue et al, 2012). Second, after adjusting for covariates (including age), Donoghue et al (2012) also reported significant associations between TGUG time and speed of processing. Furthermore, although there is a lack of research on the association of mobility and cognition in older adults with schizophrenia, a small (n=17) study in patients with early schizophrenia (mean age 30) showed a significant univariate association between TGUG time with cognitive function (measured with the MMSE and a Frontal Assessment Battery) (Lallart et al, 2012).…”

Section: Discussionmentioning

confidence: 92%

Association between schizophrenia symptoms and neurocognition on mobility in older adults with schizophrenia

Leutwyler

Hubbard

Jeste

et al. 2014

Aging & Mental Health

View full text Add to dashboard Cite

“…Hence, researchers [1][2][3][4] using different indexes such as reaction time and error rate are try ing to correct these factors. The reaction t ime is an important index that is usually used in the tests of human performance such as Simp le Reaction Time test (SRT) [5], Diagnostic Reaction Time test (DRT), Choice Reaction Time test (CRT) [5,6], Continuous Performance Task (CPT) [7], Test of Variab les of Attention (TOVA) [8,9], Attention Network Test (ANT) [9][10][11] and Wisconsin Card Sort ing Test (WCST) [1]. In fact, this index is applied for measuring the amount of normality (e.g.…”

Section: Introductionmentioning

confidence: 99%

The Effects of Beta-I and Fractal Dimension Neurofeedback on Reaction Time

Karimoi¹,

Karimoi²

2014

IJISA

View full text Add to dashboard Cite

Abstract-In this paper, we evaluate the effects of neurofeedback training protocols of the relative power of the beta-I band and the fractal dimension on the reaction time of human by the Test of Variables of Attention (TOVA) to show which of these two protocols have the great ability for the improving of the reaction time. The findings of this research show that both protocols have a good ability (p < 0.01) to improving of the reaction time and can create the significant difference (as mean dRT = 37.3 ms for the beta-I protocol and dRT = 19.6 ms for the fractal protocol) in the reaction time. Of course, we must express, the Beta-I protocol has the more ability to improving of the reaction time and it is able to provide a faster reaction time.

show abstract

Association Between Timed Up‐and‐Go and Memory, Executive Function, and Processing Speed

Cited by 136 publications

References 31 publications

Gait Measures as Predictors of Poststroke Cognitive Function

Gait Measures as Predictors of Poststroke Cognitive Function

Association between schizophrenia symptoms and neurocognition on mobility in older adults with schizophrenia

The Effects of Beta-I and Fractal Dimension Neurofeedback on Reaction Time

Contact Info

Product

Resources

About