Association between viral infection other than human papillomavirus and risk of esophageal carcinoma: a comprehensive meta-analysis of epidemiological studies

Epidemiological evidence and association of human papillomavirus with esophageal cancer in northeastern Thailand: a case–control study

“…The four main public databases including PubMed, SCOPUS, Excerpta Medica database (EMBASE), and Cochrane Library were restricted in English until 31 September 2022 using the combination of medical subject headings (MeSH; “esophageal neoplasms”) OR the following keywords in [All Fields] of (“esophagus” AND “cancer”) OR (“esophageal cancer”) OR (“esophagus” AND “neoplasm”) OR (“ESCC”) OR (“EC”) AND (“human papillomavirus”) OR (“HPV”; Petrelli et al, 2021 ; Geng et al, 2022 ). In addition, the reference lists from previous systematic reviews and recovered articles were also checked.…”

“…Furthermore, the bias risk of all included studies was separately validated by the three reviewers using the Newcastle–Ottawa Scale (NOS) guidelines ( Wells et al, 2014 ). Of these, 9 points are the maximum NOS score, and the high-quality articles had to be considered as scored 6 ( Wells et al, 2014 ; Geng et al, 2022 ). All analyses were performed on previously published articles; thus, both ethical documents and the consent forms of the patients were not mandatory.…”

Hepatitis B virus infection: An insight into the clinical connection and molecular interaction between hepatitis B virus and host extrahepatic cancer risk

“…Similarly, the role of HBV infection in esophageal cancer has been evaluated. The most recent meta-analysis, which involved 10 studies (142,437 cases and 1,382,254 controls) (10) confirmed that HBV infection patients had significantly increased esophageal cancer risk ( adjusted OR = 1.19, 95%CI: 1.01-1.36). However, another hospital-based study (98) determined that HBV infection (referred to as HBsAgseropositive) was a favorable prognostic factor for OS and disease-free survival (DFS) in patients with operable esophageal squamous cell carcinoma (DFS: adjusted HR = 0.79, 95%CI: 0.66-0.94; OS: adjusted HR = 0.80, 95%CI: 0.65-0.95).…”

“…Compelling evidence highlighted the fact that virus infection, particularly human papillomavirus (HPV) infection, could be involved in esophageal cancer development and progress (10,(93)(94)(95)(96)(97). Similarly, the role of HBV infection in esophageal cancer has been evaluated.…”

“…An epidemiological report evaluating the cancer deaths and cases in China attributable to lifestyle factors and infections revealed that HBV infection accounted for 12% and 7% of cancer-associated mortality in men and women, respectively (7). Recent large-scale population-based studies and meta-analyses have detailed these under-estimated connections (8)(9)(10)(11)(12). For example, a Chinese prospective cohort study reported that the HBsAg-seropositive population had a significantly increased stomach cancer, colorectal cancer, oral cancer, pancreatic cancer, and lymphoma risk as compared with the HBsAg-seronegative population (13).…”