Association of a Clearly Visible Subpapillary Plexus with Other Peculiarities of the Nailfold Skin in Some Schizophrenic Patients

Hr, Maricq

doi:10.1159/000253978

Cited by 22 publications

(7 citation statements)

References 6 publications

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“…One possible reason for this state of affairs is that its aetiology and meaning seem obscure. Maricq (1969) has hypothesized that the glossy, thin, transparent skin seen in individuals with this trait may reflect a trophic disorder stemming from reduced blood flow to the nailfold. This could be due to a combination of factors such as the pre-existing structural characteristics of nailfold skin, increased sympathetic tone leading to vasomotor constriction, and the special sensitivity of the small nailfold vessels to circulatory biogenic amines that are known to have vasoconstrictive effects.…”

Section: Nail Fold Capillary Visibilitymentioning

confidence: 99%

Psychophysiologic markers of psychopathology: A review.

Iacono¹

1985

Canadian Psychology / Psychologie canadienne

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Research criteria for the identification and evaluation of a characteristic as a genetic marker of the functional psychoses are specified. Each of five psychophysiologic variables (smoothpursuit eye tracking, nailfold capillary visibility, electrodermal nonresponding, reducing/ augmenting of the visual evoked potential, and resting EEG) is reviewed for its marker potential. All five characteristics have been found to hold promise as genetic markers for schizophrenia and/or the major affective disorders. Some suggestions for future research are made.

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Section: Nail Fold Capillary Visibilitymentioning

confidence: 99%

Psychophysiologic markers of psychopathology: A review.

Iacono¹

1985

Canadian Psychology / Psychologie canadienne

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“…The apparent parallel variations in PVS and clinical status could be explained by an increased effect of autonomic or humoral factors (resulting from the interaction of s and P and perhaps stress related) on the nailfold skin vasculo-connective tissue complex in HS, thus leading to greater variations than in LS, LN and HN. That more than capillary morphology is involved in LS and HS dif-Eerence, can be seen from our earlier observations on the gross appearance of nailfold skin and on capillary fragility (Maricq 1969a(Maricq , 1969b).…”

Section: The Present Hypothesis For Hereditary Transmission Of Schizomentioning

confidence: 75%

“…As a group, schizophrenics with a high PVS are different from those with a low PVS in several somatic and behavioral traits ( Maricq (1963, 1966), Maricq et al (1968, Maricq (1969aMaricq ( , 1969bMaricq ( , 1969cMaricq ( , 1970bMaricq ( , 1974, Maricq & Edelberg (1975)). They appear more seriously ill than patients with low PVS, have a poorer premorbid history and are further apart from normal controls than the low PVS schizophrenics on such variables as transformation of cultured lymphocytes, finger blood flow, skin temperature and galvanic skin response (GSR) activity (Maricq et al (1968), Maricq (1974, unpublished data), Maricq & Edelberg (1975)).…”

Section: Somatic and Behavioral Traits Associated With High Pvsmentioning

confidence: 99%

A Two‐gene Model for Schizophrenia With the Possibility to Detect Carriers of the Modifier Gene

Maricq

1975

Acta Psychiatr Scand

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A two-gene model for the hereditary transmission of schizophrenia is presented involving two pairs of autosomal alleles Ss and Pp. It is hypothesized that the recessive gene can produce schizophrenia in homozygous state with a penetrance of .40. In the presence of the gene P schizophrenia can occur in the heterozygote Ss, resulting in a more serious form of the disease and having a manifestation rate of .70. The population frequencies best fitting the available data are estimated to be approximately .03 for P and .07 or .08 for s. It is also hypothesized that the reproductive fitness is .80 in manifest schizophrenics with genotype ss pp and .50 in overt schizophrenics carrying the modifier gene P. The model is proposed to cover only the so-called "process" or "nuclear" type of schizophrenia. The remaining schizophrenics of "reactive" and other types may belong to different genotypes or consist in phenocopies. The model is discussed in relation to literature observations and our own previous studies. The possibilities for increased fitness of non-schizophrenic carriers of P and s are also discussed.

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“…It may be relevant to note that Maricq [8] reported that many schizophrenics demon strated clearly visible and extensive subpapillary plexuses in the proximal nail folds, and capillary haemorrhages had frequently been noted.…”

Section: Discussionmentioning

confidence: 99%

Nail Bleeding Associated with Neurological Diseases: All That Uncommon?

Baran

Goettmann²

1993

Dermatology

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We report 3 patients, without bleeding disorders, presenting with onychomadesis and focal haemorrhages at multiple proximal nail folds or in the nail tissue. In one of our patients it was possible to check the appearance of a drop of blood on each side, beneath the proximal nail fold when he pressed the pulp of the fingers of his previously fractured forearm on a hard surface. All patients had major peripheral or major peripheral and central neurological deficits, prior to the nail bleeding. Peripheral vascular dilatation produced by paralysis of the vasoconstrictors in the nail area slows the venous return in the dilated vessels, mainly in the proximal nail fold.

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Association of a Clearly Visible Subpapillary Plexus with Other Peculiarities of the Nailfold Skin in Some Schizophrenic Patients

Cited by 22 publications

References 6 publications

Psychophysiologic markers of psychopathology: A review.

Psychophysiologic markers of psychopathology: A review.

A Two‐gene Model for Schizophrenia With the Possibility to Detect Carriers of the Modifier Gene

Nail Bleeding Associated with Neurological Diseases: All That Uncommon?

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