Association of a Liberal Fasting Policy of Clear Fluids Before Surgery With Fasting Duration and Patient Well-being and Safety

Abstract

ImportanceCurrent fasting guidelines for procedures under anesthesia are poorly implemented, leading to negative metabolic sequelae. Recent studies in children showed support of liberal clear fluid intake; adult physiology can support clear fluid intake, but implementation studies are lacking.ObjectiveTo evaluate the successfulness of implementation of a liberal clear fluid policy with regard to fasting duration, well-being, and safety in adults scheduled for anesthesia.Design, Setting, and ParticipantsThis was a quality improvement study conducted from January 2016 to July 2021 at a tertiary referral hospital in the Netherlands. Adults scheduled for nonemergency procedures under anesthesia were included in the study. Patients undergoing obstetrics procedures or those who were intubated preoperatively were excluded.InterventionsStepwise introduction of a liberal fluid fasting policy, allowing for ingestion of clear fluids until arrival at the operating room.Main Outcomes and MeasuresThe primary outcome was change in fasting duration. Secondary outcomes were patient well-being, measured as preoperative thirst, amount of fluid ingested, postoperative nausea and vomiting (PONV), and administration of antiemetics. Safety was measured as incidence of regurgitation and aspiration (pneumonia).ResultsOf the 76 451 patients (mean [SD] age, 56 [17] years; 39 530 male individuals [52%] 36 921) included in the study, 59 036 (78%) followed the standard policy, and 16 815 (22%) followed the liberal policy. Time series analysis showed an estimated fasting duration decrease of 3:07 hours (IQR, 1:36-7:22; P < .001) after implementation of the liberal policy. Postimplementation median (IQR) fasting duration was 1:20 (0:48-2:24) hours. The incidence of regurgitation changed from 18 (95% CI, 14-21) to 24 (95% CI, 17-32) in 10 000 patients, and the incidence of aspiration changed from 1.7 (95% CI, 0.6-2.7) to 2.4 (95% CI, 0.5-4.7) in 10 000 patients. In the liberal policy, thirst feelings decreased (37% [4982 of 8615] vs 46% [3373 of 7362]; P < .001). PONV incidence decreased from 10.6% (6339 of 59 636) to 9.4% (1587 of 16 815; P < .001) and antiemetic administration decreased from 11.0% (6538 of 59 636) to 9.5% (1592 of 16 815; P < .001).Conclusions and RelevanceResults of this quality improvement study suggest that a liberal fasting policy was associated with a clinically relevant reduction in fasting duration and improved patient well-being with regard to preoperative thirst and PONV. Although a slightly higher incidence of regurgitation could not be ruled out, wider implementation of such a policy may be advocated as results are still within the clinically accepted risks margins. Results suggest that surgical procedures in patients who drink clear fluids within 2 hours before anticipated anesthesia should not be postponed or canceled.

Understanding the Purpose and Effects of a Liberal Fasting Policy of Clear Fluids Before Surgery—Reply

“…Thanks to our extensive implementation period, we were able to prove a sustainable change. We also agree that our study was still underpowered to assess the incidence of regurgitation or aspiration and addressed this limitation in the Discussion …”

Unrestricted drinking before surgery: a structured patient interview

“…Unrestricted intake of clear liquids before induction of anaesthesia has been shown to reduce the incidence of postoperative nausea and vomiting [6,7], a predictor of patient dissatisfaction with anaesthesia [7,8]. Only 2.8% of our patients required an anti-emetic in the recovery room.…”

Understanding the Purpose and Effects of a Liberal Fasting Policy of Clear Fluids Before Surgery

“…To the Editor We are writing in regards to the recent article by Marsman et al, which was recently presented at CRAMsurg, an online journal club based in the United Kingdom. We congratulate the authors on the effort for performing this large cohort study on a relevant topic.…”