Association of activity behaviours and patterns with cardiovascular risk factors in Swiss middle-aged adults: The CoLaus study

Gubelmann, Cédric; Antiochos, Panagiotis; Vollenweider, Péter; Marques‐Vidal, Pedro

doi:10.1016/j.pmedr.2018.05.012

Cited by 7 publications

(7 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1 Percentage of participants with 0, 1, 2, 3 or 4-5 of 5 predefined cardiovascular risk factors in six cohorts of middle-aged women examined in : 1980, 1985, 1990, 1995, 2003-2004 and 2013-2014 high level of physical activity was associated with a favourable cardiovascular risk profile. This was seen, even if the activity was only concentrated at weekends or was concomitant with an otherwise highly sedentary lifestyle [27].…”

Section: Bmi Body Mass Index;mentioning

confidence: 96%

Secular trends in cardiovascular risk factors among women aged 45–54 years in Gothenburg, Sweden, from 1980 to 2014

et al. 2020

View full text Add to dashboard Cite

Background A declining trend in mean cholesterol levels and smoking has been observed in high-income western countries during the last few decades, whereas obesity rates have increased. Simultaneously, mortality from coronary heart disease has decreased. The aim of the present study was to determine whether the trends in cardiovascular risk factors have continued in successive cohorts of middle-aged women over a period of 34 years. Methods Six population-based, cross-sectional samples of women (n = 2294) mean age: 49.8 years (range: 45–54), living in Gothenburg, Sweden, were investigated between 1980 and 2014. Results Body mass index (BMI) increased over time, with a mean BMI of 24.7 kg/m2 in 1980 to 25.7 kg/m2 in 2013–2014, corresponding to a weight gain of 4.5 kg, together with an increase in the proportion of obese individuals (BMI ≥ 30 kg/m2) from 10.4 to 16.6% (p = 0.0012). The proportion of smokers and women with hypertension decreased from 34.5 to 12.8% (p = 0.0006) and from 37.7 to 24.5% (p < 0.0001) respectively. Mean total serum cholesterol levels decreased from 6.23 (SD 1.09) mmol/L in 1980 to 5.43 (SD 0.98) mmol/L in 2013–2014 (p < 0.0001). Self-reported leisure time regular exercise increased from 7.8% in 1980 to 35.6% in 2013–2014 (p < 0.0001). For women born in 1963, the prevalence ratio of not having any of five major cardiovascular risk factors was 1.82 (95% confidence interval (CI) 1.38–2.41), compared with women born in 1925–1934. Conclusion The trend towards increasing obesity, more leisure-time physical activity and less smoking remains, while the decrease in serum cholesterol appears to have abated.

show abstract

Section: Bmi Body Mass Index;mentioning

confidence: 96%

Secular trends in cardiovascular risk factors among women aged 45–54 years in Gothenburg, Sweden, from 1980 to 2014

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Physical activity was measured with a wrist-worn triaxial accelerometer (GENEActiv, Activinsights Ltd., United Kingdom) for 14 consecutive days 99 . We averaged the daily time in minutes spent in moderate-to-vigorous physical activity across all days with at least 10 h of diurnal wear-time, only when there were at least 5 such weekdays and 2 weekend days.…”

Section: Methodsmentioning

confidence: 99%

Topography of associations between cardiovascular risk factors and myelin loss in the ageing human brain

et al. 2023

Self Cite

View full text Add to dashboard Cite

Our knowledge of the mechanisms underlying the vulnerability of the brain’s white matter microstructure to cardiovascular risk factors (CVRFs) is still limited. We used a quantitative magnetic resonance imaging (MRI) protocol in a single centre setting to investigate the cross-sectional association between CVRFs and brain tissue properties of white matter tracts in a large community-dwelling cohort (n = 1104, age range 46–87 years). Arterial hypertension was associated with lower myelin and axonal density MRI indices, paralleled by higher extracellular water content. Obesity showed similar associations, though with myelin difference only in male participants. Associations between CVRFs and white matter microstructure were observed predominantly in limbic and prefrontal tracts. Additional genetic, lifestyle and psychiatric factors did not modulate these results, but moderate-to-vigorous physical activity was linked to higher myelin content independently of CVRFs. Our findings complement previously described CVRF-related changes in brain water diffusion properties pointing towards myelin loss and neuroinflammation rather than neurodegeneration.

show abstract

“…In addition to the "stroke prevention campaign" in 2001, there were only few other investigations of cardiovascular risk factors in Switzerland, all studying selected cohorts and not analyzing sex differences [27][28][29][30].…”

Section: Traditional Vascular Risk Factors and Lifestyle Factorsmentioning

confidence: 99%

Neurovascular disease in Switzerland: 10‐year trends show non‐traditional risk factors on the rise and higher exposure in women

Hänsel

Steigmiller

Luft

et al. 2022

Euro J of Neurology

View full text Add to dashboard Cite

Background and purpose Effective risk factor modification is the prerequisite to prevent neurovascular disease such as stroke or vascular dementia. Non‐traditional vascular risk factors (nt‐vrfs) including stress significantly add to the risk of neurovascular disease arising from traditional vascular risk factors (t‐vrfs). In order to discover sex‐specific changes that may underlie previously reported inclines in the prevalence of neurovascular and cardiovascular disease in women, 10‐year trends in the prevalence of vrfs in Switzerland were assessed. Methods Anonymized data from 22,134 participants (51% women) of the governmental Swiss Health Survey, performed every 5 years (2007, 2012 and 2017), were obtained. Epidemiological parameters, t‐vrfs and nt‐vrfs were analyzed in a cross‐sectional study design. Results Over the observation period, the number of women having full‐time jobs increased considerably (2007 38%, 2012 39%, 2017 44%). This was accompanied by a substantial rise in the prevalence of nt‐vrfs in women and men including stress at work (2007, not available; 2012 women/men 58%/60%; 2017 women/men 66%/65%), low locus of control (women/men: 2007 21%/19%, 2012 22%/19%, 2017 25%/22%) and sleep disorders (women/men: 2007 30%/22%, 2012 28%/20%, 2017 32%/26%). Amongst t‐vrfs, only the prevalence of obesity and hypercholesterolemia increased over time in both sexes, whilst other t‐vrfs remained stable (hypertension [27%], diabetes [5%]) or decreased (smoking [9.4 cigarettes/day]). Conclusions A rise in women's economic participation alongside a higher affection with nt‐vrfs in the female Swiss population emphasizes the need to improve vascular risk stratification and implement effective preventive measures for neurovascular and cardiovascular disease.

show abstract

Association of activity behaviours and patterns with cardiovascular risk factors in Swiss middle-aged adults: The CoLaus study

Cited by 7 publications

References 28 publications

Secular trends in cardiovascular risk factors among women aged 45–54 years in Gothenburg, Sweden, from 1980 to 2014

Secular trends in cardiovascular risk factors among women aged 45–54 years in Gothenburg, Sweden, from 1980 to 2014

Topography of associations between cardiovascular risk factors and myelin loss in the ageing human brain

Neurovascular disease in Switzerland: 10‐year trends show non‐traditional risk factors on the rise and higher exposure in women

Contact Info

Product

Resources

About