Association of alignment variables, posteromedial tibial cartilage wear and anterior cruciate ligament insufficiency in participants with varus knee osteoarthritis: a cross-sectional study

Mortazavi, Seyed Mohammad Javad; Vosoughi, Farzad

doi:10.1007/s00264-022-05358-5

Cited by 10 publications

(8 citation statements)

References 22 publications

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“…15° may be the limit value for the occurrence of varus deformity. Related literature studies have shown that as the varus deformity worsens beyond 13-17°, the wear is more likely to involve the center medial and posterior medial regions of the tibial plateau [31], and posterior medial tibial wear occurs in ACL injuries, excessive varus deformity, with an varus angle of 15.5 as a threshold for identifying posterior medial tibial wear and an varus angle of 14.5° as a threshold for detecting ACL de ciencies [32]. All of these ndings are highly consistent with our ndings.…”

Section: Discussionmentioning

confidence: 99%

Analysis of cartilage loading and injury correlation in Knee varus deformity

Zhang,

Ma,

Tian

et al. 2023

Preprint

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Objective: The purpose of this study is to construct three-dimensional simulation models of Knee osteoarthritis (KOA) with different varus angles by applying computer-aided design (CAD); to analyse the stress distribution in the knee joint cavity by using finite elements through the KOA models of different varus, and to compare the internal loads in the knee joints of different models; and to carry out a correlation analysis of the results of the finite element analyses in conjunction with the corresponding clinical cases of varus and cartilage injuries. Methods: The CAD software package Mimics 21.0 was used to accurately simulate different varus angle models, and the simulated varus angles were divided into (0°,3°,6°,9°,12°,15°,18°) seven knee models, which were processed with finite element software, and axial forces were applied by simulating the weight of the human body in the static extension position, and the cartilage of the femoral condyle, medial tibial plateau, and lateral plateau were obtained. Von-Mises Stress (VMS) distribution and peak conditions, combined with clinical cases of the same varus deformity angle intraoperative microscopic visualization of cartilage cartilage injury, to find the cartilage force and injury correlation. Results: Under a compression load of 740N, the lower limb mechanical axis shifted inward as the varus angle increased；the peak VMS of the lateral tibial plateau and femoral condyles did not change much from 3°-18°, the peak cartilage VMS of the medial tibial plateau was higher than that of other intercompartments；The medial tibial plateau had the largest stress area at 0°, with a 2.6-fold increase in peak VMS from 4.13-14.05MPa from 0°-6°, and the stress loads basically stabilized from 6°-15°. Clinical data showed that the varus deformity angle was significantly correlated with cartilage damage in the knee, medial plateau, and patellofemoral intercompartment ( F1=52.287,P1<.001 ,h12 =.709 , F2=312.67,P2<.001 ,h22 =.729, F3=55.486,P3<.001 ,h32 =.691) Conclusion: The larger the varus deformity angle, the higher the medial cartilage stress load, the heavier the cartilage damage in the corresponding peak stress area. In actual clinical patients, when varus exceeds 6°, in addition to sagittal plane medial plateau cartilage damage there was also coronal plane patellofemoral intercompartmental cartilage damage, and there was a situation of articular coronal plane motion, and the knee injury appeared abnormal when it exceeded 15°, which could be deduced that there was an abnormal motion of the knee joint. The probability of cartilage damage increases when the varus is ≥6°, and early surgical correction is recommended to prevent aggravation of the deformity and thus restore knee function.

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Section: Discussionmentioning

confidence: 99%

Analysis of cartilage loading and injury correlation in Knee varus deformity

Zhang,

Ma,

Tian

et al. 2023

Preprint

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“…Whereas anteromedial wear appeared to correspond with the classic description of constitutional varus, posteromedial wear demonstrated a rather neutral to slight varus alignment in combination with a more pronounced posterior tibial slope. Multiple authors linked greater posterior tibial slope to an increased ACL rupture risk (Lansdown and Ma, 2018;Kim et al, 2019;Mortazavi and Vosoughi, 2022). As the femoral condyle translation increases, the ACL is forced to elongate and the tension placed on the ligament intensifies (Lansdown and Ma, 2018).…”

Section: Discussionmentioning

confidence: 99%

Wear patterns in knee OA correlate with native limb geometry

Oevelen

Borre

Duquesne

et al. 2022

Front. Bioeng. Biotechnol.

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Background: To date, the amount of cartilage loss is graded by means of discrete scoring systems on artificially divided regions of interest (ROI). However, optimal statistical comparison between and within populations requires anatomically standardized cartilage thickness assessment. Providing anatomical standardization relying on non-rigid registration, we aim to compare morphotypes of a healthy control cohort and virtual reconstructed twins of end-stage knee OA subjects to assess the shape-related knee OA risk and to evaluate possible correlations between phenotype and location of cartilage loss.Methods: Out of an anonymized dataset provided by the Medacta company (Medacta International SA, Castel S. Pietro, CH), 798 end-stage knee OA cases were extracted. Cartilage wear patterns were observed by computing joint space width. The three-dimensional joint space width data was translated into a two-dimensional pixel image, which served as the input for a principal polynomial autoencoder developed for non-linear encoding of wear patterns. Virtual healthy twin reconstruction enabled the investigation of the morphology-related risk for OA requiring joint arthroplasty.Results: The polynomial autoencoder revealed 4 dominant, orthogonal components, accounting for 94% of variance in the latent feature space. This could be interpreted as medial (54.8%), bicompartmental (25.2%) and lateral (9.1%) wear. Medial wear was subdivided into anteromedial (11.3%) and posteromedial (10.4%) wear. Pre-diseased limb geometry had a positive predictive value of 0.80 in the prediction of OA incidence (r 0.58, p < 0.001).Conclusion: An innovative methodological workflow is presented to correlate cartilage wear patterns with knee joint phenotype and to assess the distinct knee OA risk based on pre-diseased lower limb morphology. Confirming previous research, both alignment and joint geometry are of importance in knee OA disease onset and progression.

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“…Through the t-test of two independent samples, P < 0.05, it shows that there is a significant difference between the release angle after the experiment of scheme 1 and the release angle after the experiment of scheme 2, which shows that the release technology after the experiment of scheme 1 is significantly better than the result after the experiment of scheme 2, and the training method of one-time incremental load has a better effect on the learning of throwing technology. 8 As can be seen from Figure 1, the results of scheme I and scheme II after the experiment are compared. The hand angle of scheme I after the experiment is 36.90 °, and that of scheme II after the experiment is 31.20 °.…”

Section: Release Anglementioning

confidence: 99%

Influence of Upper Body Stretching Exercises on Shot Put

Teng

Chen

Xie

et al. 2023

Rev Bras Med Esporte

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Introduction The technique in the shot put and the ability in the throwing stage are two important factors that determine the ability of athletes. Qualified experts and coaches attach great importance to training and research on the ability of the throwing stage and the ability to throw. Objective Compare gravity load training and single incremental load training through practical means, analyzing the impacts on throwing ability in athletes. Methods The self-assessment method was used to conduct the comparative experiment on different forms of strength training in 20 college students. The experimental scheme adopts the single incremental load strength training, and the control scheme adopts the traditional barbell training. Results : After the experiment, the hand angle of group I was significantly higher than that of group II (P < 0.05); after the experiment, the shoulder angle of group I was significantly higher than that of group II (P < 0.05); after the experiment, the performance of the seated shot placed in group I was significantly higher than that of group II (P < 0.05), and there was no significant difference in the standing performance (P > 0.05). Conclusion Single incremental load training can significantly improve the throwing ability of shot put athletes. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.

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Association of alignment variables, posteromedial tibial cartilage wear and anterior cruciate ligament insufficiency in participants with varus knee osteoarthritis: a cross-sectional study

Cited by 10 publications

References 22 publications

Analysis of cartilage loading and injury correlation in Knee varus deformity

Analysis of cartilage loading and injury correlation in Knee varus deformity

Wear patterns in knee OA correlate with native limb geometry

Influence of Upper Body Stretching Exercises on Shot Put

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