Association of anthropometric measures of obesity and chronic kidney disease in elderly women

Abstract

Introduction and objective. Growing evidence suggests that obesity is an important contributor to the development of chronic kidney disease (CKD). The relationship between obesity and CKD is complex and not completely understood, and the best anthropometric index of obesity in predicting CKD is controversial. This study aimed to determine the best anthropometric index of obesity in predicting CKD in a population of elderly women. Materials and methods. Anthropometric indexes of obesity including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WheiR) and waist-to-hip-ratio (WHR), were obtained in 730 selected females. Biochemical measurements including blood glucose, lipid profile, and 2-h postprandial blood glucose were performed. GFR was estimated by using CKD-EPI equation. Results. The prevalence of CKD stage ≥ 3 was 12.2%. Overweight and obesity was found in 50% and 36% of participants, respectively. Increased central fat distribution, as defined by WheiR, WC and WHR, was found in 89.6%, 91.7% and 89.4% individuals, respectively. Univariate linear regression analysis showed positive correlations between CKD and age (p<0.001), BMI (p<0.001), WC (p<0.001), WHR (p=0.007), WheiR (p<0.001), diabetes (p=0.002), as well as triglicerydes (p=0.031), and negative correlation between CKD and HDL level (p=0.017). Multivariable analysis demonstrated that hypertension, diabetes, WC and WheiR were independent predictors of CKD. The area under the receiver operating characteristics curve was best for WheiR (0.647), followed by WC (0.620), BMI (0.616), and WHR (0.532). Conclusions. Abdominal obesity is an important predictor of CKD. Of commonly used anthropometric parameters of obesity WheiR ≥ 0.6 is particularly associated with CKD in elderly females.

Comparison of visceral, body fat indices and anthropometric measures in relation to chronic kidney disease among Chinese adults from a large scale cross-sectional study

“…A related study conducted among female subjects aged 65–80 years found that WHtR was a better index associated with CKD when comparing with other common adiposity indices (BMI, WC, waist-to-hip ratio) [ 23 ]. Dai et al suggested that a visceral adiposity index was superior to BMI and WC for predicting CKD in females [ 24 ].…”

Cardiovascular risk factors in chronic renal failure patient at Soavinandriana Hospital Antananarivo

“…15,20 Jaroszynski's study showed the existence of a relationship between incidence of CKD and obesity (p<0.001). 21 Obesity contributes to serious morbidities and leads to increased disability and mortality. Weight loss in obese patients is essential to reduce the rate of cardiovascular morbidity.…”

Features of translation of some rarely used anthropometric terms from Ukrainian into English

“…Nowadays, anthropometric researches have confidently taken its place in medicine. So they are useful not only for health assessment, but also are used in many fields: forensic medicine (to estimate the age of the subject) [13], forensic dentistry (it is an interdiscipline of forensic medicine and stomatology) for the identification of individual and age estimation [24], dentistry (anthropometric diagnostic methods of dentognathic anomaly, and there is potential correlation among number of teeth, chewing ability and anthropometric profile) [7,9,29], pediatrics, obstetrics and gynecology [17,21,27], as well as for the diagnosis of overweight (important indicators of nutritional status in the children and adults) [11,16,20], for sports control [22] and for the standardization purpose [3,15,23,26,30]. The symptoms of many diseases are expressed in anthropometric changes [12].…”