2024
DOI: 10.1002/clc.24273
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Association of anti‐factor Xa‐guided anticoagulation with hemorrhage during ECMO support: A systematic review and meta‐analysis

Sasa Rajsic,
Robert Breitkopf,
Benedikt Treml
et al.

Abstract: BackgroundThe use of extracorporeal membrane oxygenation (ECMO) is associated with complex hemostatic changes. Systemic anticoagulation is initiated to prevent clotting in the ECMO system, but this comes with an increased risk of bleeding. Evidence on the use of anti‐Xa‐guided monitoring to prevent bleeding during ECMO support is limited. Therefore, we aimed to analyze the association between anti‐factor Xa‐guided anticoagulation and hemorrhage during ECMO.MethodsA systematic review and meta‐analysis was perfo… Show more

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