Association of Asthma With Clinically Aggressive Recurrent Respiratory Papillomatosis

Abstract

Patients with asthma, particularly those using daily inhaled corticosteroids, may have a more clinically aggressive RRP course. The cause of this association is unclear, and clinical recommendations should not yet be made based on these data.

Prevalence of Diabetes Mellitus and Its Impact on Disease Severity in Adult Recurrent Respiratory Papillomatosis

“…Given these results, it is important to understand intrinsic patient factors that affect patient susceptibility to RRP or severity of disease. Robb et al have reported evidence that the diagnosis of asthma, or its treatment with inhaled corticosteroids, correlated with more clinically aggressive RRP 29 . Similar to asthma, DM is a common comorbid condition in the United States that affects millions.…”

Clinical course of recurrent respiratory papillomatosis: Comparison between aggressiveness of human papillomavirus-6 and human papillomavirus-11

“…In addition to HPV type, age of onset has an important influence on the disease course of RRP . Finally, also comorbidity like asthma or gastroesophageal reflux disease (GERD) can worsen the clinical course of RRP …”

Complicated tracheo-bronchial papillomatosis

“…The final histo-pathology revealed a complicated squamous respiratory papilloma with superadded infection by aspirgellosis and actinomycosis. Few cases are reported like this case in the literature especially in immune-competent patients [39,40] . However, those patients reported in the literature had recurrent respiratory papillomas not like our patient who had it for the first time.…”