Association of Autoantibodies With Smoking, Cardiovascular Morbidity, and Death in the Busselton Population

Mathews, John D.; Whittingham, Senga; Hooper, Belinda; Mackay, I. R.; Stenhouse, N. S.

doi:10.1016/s0140-6736(73)91037-4

Cited by 88 publications

(39 citation statements)

References 3 publications

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“…The few studies conducted until now have shown controversial results. A population survey in Australia showed that young smokers were at increased risk of being positive for RF (Mathews et al, 1973). The same was found by a group of Finnish researchers which stressed that this positivity was stronger in young males (Heliövaara et al, 1993).…”

Section: Introductionsupporting

confidence: 55%

Rheumatoid factor and tobacco exposure

Skare

Silva

et al. 2002

Braz. arch. biol. technol.

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Section: Introductionsupporting

confidence: 55%

Rheumatoid factor and tobacco exposure

Skare

Silva

et al. 2002

Braz. arch. biol. technol.

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“…A link between smoking and R F production has been reported previously, and the risk seems to be higher in men (17,18). In 1993, Heliovaara et a1 (19) reported outcomes in a cohort of 42,000 Finnish men and women followed up for more than 20 years.…”

Section: Discussionmentioning

confidence: 76%

Blood transfusion, smoking, and obesity as risk factors for the development of rheumatoid arthritis. Results from a primary care‐based incident case‐control study in Norfolk, England

Symmons

Bankhead

Harrison

et al. 1997

Arthritis & Rheumatism

344

179

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Objective. To examine a range of demographic, social, and clinical risk factors for the development of rheumatoid arthritis (RA).Methods. Population-based case-control study in Norfolk, England, involving adult patients, ages 18-70, with an inflammatory polyarthritis of < 12 months' duration who were recruited from the Norfolk Arthritis Register. Controls, matched for sex and date of birth, were selected from the primary care register of the Nomich Health Authority. Both cases and controls completed identical self-administered questionnaires. Matched analysis of the 165 case-control sets was conducted for the whole group and for the subset in which the cases satisfied the 1987 American College of Rheumatology criteria for RA.Results. The controls were of higher socioeconomic status than the cases. This was probably due to response bias. Having a body mass index 1 3 0 was associated with an adjusted odds ratio (OR) of 3.74 for developing RA (95% confidence interval [95% CI] 1.14-12.27). RA was also associated with a history of blood transfusion (OR 4.83, 95% CI 1.29-18.07). Even after correcting for social class, a history of having ever Supported by the Arthritis and Rheumatism Council, UK.

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“…Cigarette smoking has been known to influence the bronchoalveolar lavage (BAL) cellularity in patients with idiopathic pulmonary fibrosis (34) and asbestosis (35); indeed, smoking accounts for at least a portion of the changes in BAL cells that have previously been ascribed to the underlying lung disease. Furthermore, cigarette smoking has been associated with an elevated serum rheumatoid factor (36)(37)(38)(39), suggesting a possible direct link with RA (40). These findings led us to speculate that cigarette smoking may play a role in RA-ILD.…”

Section: Discussionmentioning

confidence: 99%

Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities

Saag

Kolluri

Koehnke

et al. 1996

Arthritis & Rheumatism

226

112

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Objective. To determine the prevalence and important clinical predictors of radiographic and physiologic abnormalities indicative of rheumatoid arthritis interstitial lung disease (RA-ILD).Methods. An unselected cohort of patients with a confirmed diagnosis of RA and known lung disease were identified (n = 336) and evaluated for RA disease activity and seventy. Outcomes included abnormalities determined by the pulmonary function tests of forced vital capacity (FVC) and diffusion capacity for carbon monoxide (DLco), and/or chest radiographic findings of interstitial infiltrates. We used multivariable statistical modeling to determine the independent significance of cigarette smoking and other RA-specific factors on the pulmonary abnormalities of interest.Results. At least 1 of the 3 abnormal findings was identified by pulmonary tests in 32.4% of all patients. These abnormal findings included an FVC <80% of predicted in 42 patients, a DLco <80% of predicted in 64 patients, and evidence of radiographic interstitial infiltrates in 40 patients. After statistical adjustment for confounding factors, pack-years of cigarette smoking remained a significant predictor of low DLco (p = Submitted for publication January 22, 1996; accepted in revised form May 2, 1996. interstitial abnormalities on chest radiograph (odds ratio for 2 2 5 pack-years = 3.76,95% CI 1.59,8.88). The Health Assessment Questionnaire (HAQ) Disability Index (DI) was also an important risk factor for the decline in both the DLco ( p = -1.15, 95% CI -2.00, -0.30) and FVC ( p = -0.23, 95% CI -032, -0.13).-

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Association of Autoantibodies With Smoking, Cardiovascular Morbidity, and Death in the Busselton Population

Cited by 88 publications

References 3 publications

Rheumatoid factor and tobacco exposure

Rheumatoid factor and tobacco exposure

Blood transfusion, smoking, and obesity as risk factors for the development of rheumatoid arthritis. Results from a primary care‐based incident case‐control study in Norfolk, England

Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities

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