Association of baseline severity of lower urinary tract symptoms with the success conservative therapy for urinary incontinence in women

A model identifying characteristics predictive of successful pelvic floor muscle training outcomes among women with stress urinary incontinence

“…Similar to our findings, Cammu and colleagues [9] found that physiotherapy intervention was more likely to fail in women who reported more severe symptoms (> 2 leakages per day). These findings are consistent with observations that women with mild to moderate SUI severity are more often cured with physiotherapy in comparison with their more severely suffering counterparts [8]. Women with more severe SUI symptoms may have more defects or more extensive defects including tissue damage, nerve damage, and/or reduced vascularization of their urethra and/or pelvic floor, making a complete cure more difficult to attain through conservative approaches.…”

“…As there is currently no standard definition of cure available in the literature, we used the same definition employed by Dumoulin et al [11]: a pad weight gain of ≤2 g on a standardized pad test post-treatment. Using this criterion, the cure rate found in this study was 49%, which is within the range of cure rates reported in previous studies 36-74% [7,8,[10][11][12]26]. Although other definitions of cure may yield different cure rates and results in predictive modeling, the use of a dry standardized pad test to operationalize the definition of cure is objective and easily replicable.…”

“…Several previous studies have generated predictive models of PFMT outcomes among women with SUI using various definitions of cure [7][8][9][10][11][12]. As there is currently no standard definition of cure available in the literature, we used the same definition employed by Dumoulin et al [11]: a pad weight gain of ≤2 g on a standardized pad test post-treatment.…”

“…Previous predictive models for PFMT outcomes among women with SUI have been generated using combinations of demographic and clinical assessments outcomes [7][8][9][10] or PFM function and morphology [11,12]. However, findings have been inconsistent, and most studies have been limited by the use of retrospective data [7,8,10,11], including more predictors than is recommended to avoid over-specification [8,10,11], and/or a lack of validation using statistical techniques or testing the model on a new sample of women [7,[9][10][11]. Further, some models have used clinically inaccessible tools such as MRI and dynamometry [12,13].…”

Self-management of incontinence using a free mobile app: factors associated with improvement

“…A higher ICIQ-UI SF score decreased the odds of great improvement, which has also been found by other studies [10,12,14,27]. However, this also depends on the outcome used, for example, Lindh et al found that women with higher ICIQ-UI SF scores were more likely to have ≥3 points reduction but less likely to be satisfied with treatment [10].…”