2002
DOI: 10.1046/j.1365-2222.2002.01380.x
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Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey

Abstract: Reported associations of body mass index with symptoms suggestive of asthma are unlikely to be explained by a higher risk of atopy in the obese. Alternative explanations must be sought.

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Cited by 130 publications
(156 citation statements)
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“…The effect modification by sex that was seen in our data (with a stronger effect among women) is not surprising given similar results already observed in other studies on air pollution and respiratory and cardiovascular disease mortality [22][23][24]. One explanation of women's greater response to air pollution may be their bronchial hyper-responsiveness to soot and pollutants [25].…”
Section: Discussionsupporting
confidence: 91%
“…The effect modification by sex that was seen in our data (with a stronger effect among women) is not surprising given similar results already observed in other studies on air pollution and respiratory and cardiovascular disease mortality [22][23][24]. One explanation of women's greater response to air pollution may be their bronchial hyper-responsiveness to soot and pollutants [25].…”
Section: Discussionsupporting
confidence: 91%
“…Two studies by National Health and Nutrition Examination Survey (NHANES III) and the European Community Respiratory Health Survey (ECRHS) found no relationship between obesity and frequency of atopy among children (31). Similarly in our study, the presence of obesity did not affect frequency of atopy and the level of FEV1 (32).…”
supporting
confidence: 77%
“…18,19 Obesity has also been linked with impaired pulmonary function and airway hyperresponsiveness, [20][21][22][23] but not in all studies. 11,24 The most convincing evidence of a causal link between obesity and asthma in adults is provided by a large prospective cohort study of 85 911 nurses followed during 1991 and 1995, in which obese women had a much greater risk of asthma, and weight gain was positively associated with the risk of developing asthma.…”
Section: Introductionmentioning
confidence: 99%